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1,601
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ShareScore release 0.9.0
Dataset results
1,601 results for “Prognosis;”
Patterns of IgH rearrangement stratify prognosis of diffuse large B-cell lymphoma, which could be associated with CDC25A
GEO Series GSE111069. Homo sapiens. 6 samples. Type: Expression profiling by array.
Analysis of Immune and Prognostic-Related lncRNA PRKCQ-AS1 for Predicting Prognosis and Regulating Effect in Sepsis
GEO Series GSE217700. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
RIPK2-Regulated Gene Signature Associated with Poor Prognosis in Prostate Cancer
GEO Series GSE292278. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Cathepsin V is correlated with the prognosis and tumor microenvironment in liver cancer
GEO Series GSE233817. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Downregulated CDH3 is significantly correlated with better prognosis from lung adenocarcinomas and decreases proliferation and migration in lung cancer cells in vitro
GEO Series GSE186405. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
High expression of circZBTB46 predicts poor prognosis in patients with myelodysplastic syndrome and acute myeloid leukemia
GEO Series GSE163386. Homo sapiens. 14 samples. Type: Non-coding RNA profiling by array.
GDF15 overexpression dreived from tumor-associated macrophages and cancer cells in the microenvironment of human esophageal squamous cell carcinoma promotes tumor growth and poor prognosis
GEO Series GSE59948. Homo sapiens. 4 samples. Type: Expression profiling by array.
RNA Binding Patterns of Ischemic Heart Failure Prognosis Indicator Eukaryotic Translation Initiation Factor 3m Reveal its Unique Role in Regulation of Nitrative Damage after Myocardial Ischemia-Reperf
GEO Series GSE217296. Homo sapiens; Rattus norvegicus. 20 samples. Type: Expression profiling by high throughput sequencing; Other.
Identification and validation of KIF20A for predicting prognosis and treatment outcomes in patients with breast cancer
GEO Series GSE280284. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Splicing Factor SRSF1 Promotes Tumorigenesis via Oncogenic Splice-Switching and Predicts Poor Prognosis in Multiple Myeloma
GEO Series GSE160724. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Impact of exosomal miR-92b in hepatocellular carcinoma: its role for cancer immunoediting and clinical value for prognosis
GEO Series GSE121357. Rattus norvegicus. 4 samples. Type: Non-coding RNA profiling by array.
TNFα-producing Macrophages Determine Subtype Identity and Prognosis via AP1 Enhancer Reprogramming in Pancreatic Cancer
GEO Series GSE172103. Homo sapiens. 4 samples. Type: Expression profiling by array.
miR-1246 association with distant metastasis and poor prognosis in breast cancer patients
GEO Series GSE68373. Homo sapiens. 64 samples. Type: Non-coding RNA profiling by array.
CXCR4 overexpression in chronic lymphocytic leukemia associates with poorer prognosis: a prospective, single-center, observational study
GEO Series GSE254015. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Cell-free DNA methylation markers in diagnosis and prognosis of common cancers (lung cancer)
GEO Series GSE97932. Homo sapiens. 654 samples. Type: Methylation profiling by high throughput sequencing.
Dataset related to article "Tumor-Infiltrating Lymphocytes and Macrophages in Intrahepatic Cholangiocellular Carcinoma. Impact on Prognosis after Complete Surgery."
<p>BACKGROUND:</p> <p>Immune infiltrate impacts prognosis of several tumors. To assess the prognostic impact of tumor-infiltrating lymphocytes and macrophages in patients undergoing resection for intrahepatic cholangiocellular carcinoma (ICC).</p> <p>METHODS:</p> <p>All consecutive patients undergoing surgery for ICC between 2008 and 2016 were considered. Inclusion criteria were complete resection and follow-up > 12 months. Tissue sections were immunostained for CD3+, CD4+, CD8+, Foxp3+, and CD68+. The number of positive cells was quantified using a computer-aided image analysis system. Different cut-off values were tested as predictors of overall survival (OS).</p> <p>RESULTS:</p> <p>Fifty-three patients were analyzed. ICC were T1 in 28 patients, multifocal in 11, and N+ in 13. After a median follow-up of 42 months, 5-year OS was 52.1%. The following immune infiltrate values were associated with better OS: CD3+ > 0.10% (5-year OS 63.3% vs. 13.6% if ≤ 0.10%, p = 0.001); CD8+ > 0.10% (56.2% vs. 28.6% if ≤ 0.10%, p = 0.051); Foxp3+ absent (59.4% vs. 16.0% if present, p = 0.049). CD4+ and CD68+ infiltrates were not associated with OS. Three-year OS rates in patients with 0, 1, and ≥ 2 negative prognostic factors were 73.6%, 47.3%, and 14.3%, respectively (p < 0.001). CD3+ infiltrate stratified prognosis in T1 tumors (3-year OS 71.7% if CD3+ > 0.10% vs. 14.3% if ≤ 0.10%, p < 0.001).</p> <p>CONCLUSIONS:</p> <p>Tumor-infiltrating lymphocytes are associated with prognosis of ICC patients after complete surgery. CD3+ and CD8+ infiltrate is associated with higher survival and lower recurrence risk, while Foxp3+ infiltrate is associated with worse prognosis. CD3+ infiltrate allows refining prediction of prognosis in early tumors.</p>
MALNC: A new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML biology, prognosis and drug response
<p>RNAseq and ChIRP-seq dataset for the manuscript "<strong><span>MALNC: A new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with <u>impact on</u> AML biology, prognosis and drug response</span></strong>".</p> <p> </p> <p>MALNC_1_ChIRPseq_peaks.xls; peak file from MCAS2 peak calling on ChIRPseq linrary replicate 1.</p> <p>MALNC_2_ChIRPseq_peaks.xls; peak file from MCAS2 peak calling on ChIRPseq linrary replicate 2.</p> <p>The overlapped peaks between two replicates were used in the manuscript.</p> <p>MALNC_RNAseq_featurecounts.tsv; bulk RNAseq count table for MALNC knock out samples. 6 sample groups: (1) WT; (2) KOA (MALNC knockout A); (3) KOB (MALNC knockout B); (4) KOC (MALNC knockout C); (5) WTRA (WT treat with ATRA); (6) KORA (MALNC knockout B treat with ATRA). Each sample group has three replicates.</p> <p> </p> <p> </p>
Dataset related to article "Copy number alterations in stage I epithelial ovarian cancer highlight three genomic patterns associated to prognosis"
<p>This record contains data related to article "Copy number alterations in stage I epithelial ovarian cancer highlight three genomic patterns associated to prognosis"</p> <p><strong>Background: </strong>Stage I epithelial ovarian cancer (EOC) encompasses five histologically different subtypes of tumors confined to the ovaries with a generally favorable prognosis. Despite the intrinsic heterogeneity, all stage I EOCs are treated with complete resection and adjuvant therapy in most of the cases. Owing to the lack of robust prognostic markers, this often leads to overtreatment. Therefore, a better molecular characterization of stage I EOCs could improve the assessment of the risk of relapse and the refinement of optimal treatment options.</p> <p><strong>Materials and methods: </strong>205 stage I EOCs tumor biopsies with a median follow-up of eight years were gathered from two independent Italian tumor tissue collections, and the genome distribution of somatic copy number alterations (SCNAs) was investigated by shallow whole genome sequencing (sWGS) approach.</p> <p><strong>Results: </strong>Despite the variability in SCNAs distribution both across and within the histotypes, we were able to define three common genomic instability patterns, namely stable, unstable, and highly unstable. These patterns were based on the percentage of the genome affected by SCNAs and on their length. The genomic instability pattern was strongly predictive of patients' prognosis also with multivariate models including currently used clinico-pathological variables.</p> <p><strong>Conclusions: </strong>The results obtained in this study support the idea that novel molecular markers, in this case genomic instability patterns, can anticipate the behavior of stage I EOC regardless of tumor subtype and provide valuable prognostic information. Thus, it might be propitious to extend the study of these genomic instability patterns to improve rational management of this disease.</p>
Construction of a necroptosis-related lncRNA signature to predict the prognosis and immune microenvironment of IDH1 wild-type GBM
<p><a href="https://zenodo.org/api/files/3b61d9b7-5c0c-4f49-acae-5ec3c5294b1e/Original%20data-Construction%20of%20a%20necroptosis-related%20lncRNA%20signature.zip">Original data</a>:Construction of a necroptosis-related lncRNA signature to predict the prognosis and immune microenvironment of IDH1 wild-type GBM.</p>
Per- and polyfluoroalkyl substances (PFASs) exposure in melanoma patients: a retrospective study on prognosis and histological features
<p>Per- and polyfluoroalkyl substances (PFASs) are endocrine disrupting chemicals and previous studies showed that they could be associated with altered vitamin D levels. Since 1965, a massive environmental contamination by PFASs has occurred in North-eastern Italy. This study compared histopathology and prognosis between melanoma patients exposed (n=194) and unexposed (n=488) to PFAS. All patients were diagnosed and/or treated for melanoma at the Veneto Oncological Institute and the University Hospital of Padua (Italy) in 1998-2014. Patients were stratified according to the area of residency and the classification provided by the regional administration. Presence of mitoses was found in 70.5% of exposed patients and 58.7% of unexposed patients (p=0.005). Median follow-up was 90 months (IQR 59-136). 5-year overall survival was 83.7% in exposed patients and 88.0% in unexposed patients (p=0.20); 5-year disease-specific survival was 88.0% in exposed patients and 90.9% in unexposed patients (p=0.50); 5-year disease-free survival was 83.8% in exposed patients and 87.3% in unexposed patients (p=0.20). Our findings suggested that exposure to PFAS was associated with higher level of mitosis in melanoma patients, which may be related to the vitamin D deficiency induced by PFAS. Further studies are required to investigate this relationship and all effects of PFAS on prognosis.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.