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2,996 results for “copd”
Figure 2 from: Tachkov K, Mitov K, Savova A (2019) Predicting the outcomes and costs for a cohort of 426 patients with Chronic Obstructive Pulmonary Disease (COPD) in Bulgaria through a Markov model. Pharmacia 66(2): 53-57. https://doi.org/10.3897/pharmacia.66.e35162
Figure 2 CEAC of all data points
Figure 1 from: Tachkov K, Mitov K, Savova A (2019) Predicting the outcomes and costs for a cohort of 426 patients with Chronic Obstructive Pulmonary Disease (COPD) in Bulgaria through a Markov model. Pharmacia 66(2): 53-57. https://doi.org/10.3897/pharmacia.66.e35162
Figure 1 ICER points and dispersion cloud of Monte-Carlo simulation
Figure 3 from: Tachkov K, Mitov K, Savova A (2019) Predicting the outcomes and costs for a cohort of 426 patients with Chronic Obstructive Pulmonary Disease (COPD) in Bulgaria through a Markov model. Pharmacia 66(2): 53-57. https://doi.org/10.3897/pharmacia.66.e35162
Figure 3 Tornado diagram for QALYs
Data Set for Manuscript: Citrullination, a novel post-translational modification of elastin, is involved in COPD Pathogenesis
<p>Elastin is an extracellular matrix protein (ECM) that supports elasticity of the lung, and in patients with chronic obstructive pulmonary disease (COPD) and emphysema, the structural changes that reduce the amount of elastic recoil, lead to loss of pulmonary function. We recently demonstrated that elastin is a target of peptidyl arginine deiminase (PAD) enzyme-induced citrullination, thereby leading to enhanced susceptibility of this ECM protein to proteolysis. The current study aimed to investigate the impact of PAD activity in vivo and furthermore assessed whether pharmacological inhibition of PAD activity protects against pulmonary emphysema. </p>
Dataset related to: "Upper-limb interval versus constant-load exercise in patients with COPD: a physiological crossover study"
<p>We provide the raw data used for the following article:</p> <p>Paneroni M, Vogiatzis I, Cavicchia A, Salvi B, Bertacchini L, Venturelli M, Vitacca M. <strong>Upper-limb interval <em>versus</em> constant-load exercise in patients with COPD: a physiological crossover study. </strong>ERJ Open Res. 2024 Feb 26;10(1):00779-2023. doi: 10.1183/23120541.00779-2023. </p> <h2>Abstract</h2> <div> <p><strong>Objective: </strong>Upper-limb exercise is recommended for patients with COPD, albeit there are limited data concerning the optimal modality to implement. We compared interval (INT-EX) to continuous (CONT-EX) upper-limb exercise in terms of exercise tolerance, ventilatory and metabolic responses when both conditions were sustained at an equivalent work rate.</p> <p><strong>Methods: </strong>26 stable COPD patients undertook three upper-limb exercise sessions to initially establish peak work rate (PWR) <em>via</em> an incremental exercise test and subsequently two equivalent work rate tests to the limit tolerance in balanced order: 1) INT-EX consisting of 30-s work at 100% PWR interspersed with 30-s work at 40% of PWR; and 2) CONT-EX at 70% PWR.</p> <p><strong>Results: </strong>20 patients (76.9%) had longer tolerance during INT-EX, while six out of 26 (23.1%) exhibited longer tolerance during CONT-EX. The average endurance time was 434.1±184.7 and 315.7±128.7 s for INT-EX and CONT-EX, respectively. During INT-EX at isotime (<em>i.e.</em> when work completed was the same between INT-EX and CONT-EX), the majority of patients manifested lower oxygen uptake, minute ventilation, pulmonary hyperinflation, heart rate, symptoms and higher CO<sub>2</sub> blood concentration. Patients with longer INT-EX had a lower comorbidity score (Cumulative Illness Rating Scale: 1.58±0.30 <em>versus</em> 1.88±0.29, p=0.0395) and better-preserved lung function (forced vital capacity 84.7±15.31% <em>versus</em> 67.67±20.56%, p=0.0367; forced expiratory volume in 1 s 57.15±14.59 <em>versus</em> 44.67±12.99% predicted, p=0.0725) compared to patients with longer CONT-EX.</p> <p><strong>Conclusion: </strong>INT-EX is more sustainable than CONT-EX for the majority of COPD patients with moderate obstruction, leading to lower dynamic hyperinflation and symptoms at isotime. Further studies need to define the benefits of its application during pulmonary rehabilitation.</p> <p> </p> </div>
COPD Data set
<p>Data set of COPD disease</p>
Respiratory Rehabilitation and Sleep Quality in COPD Patients
ClinicalTrials.gov study NCT06677268. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Effects of a 4-week Acu-Transcutaneous Electrical Nerve Stimulation (Acu-TENS) Program on Subjects With Stable Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov study NCT00971490. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Registry of COPD Patients From Outpatient Polyclinic Healthcare Institutions of the Russian Federation in Moscow
ClinicalTrials.gov study NCT02853383. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Eccentric Exercise Training in Patients With COPD
ClinicalTrials.gov study NCT06168266. IPD Sharing: NO. Countries: 1. Publications: 0.
Impact of Kolcaba Comfort Theory Training on Dyspnea, Function, and Comfort in COPD Patients
ClinicalTrials.gov study NCT06588361. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Prednisone Reduction in ICU Patients With COPD Exacerbation
ClinicalTrials.gov study NCT03981081. IPD Sharing: NO. Countries: 2. Publications: 0.
Efficacy of High-intensity NPPV and Low-intensity NPPV in Patients With Chronic Hypercapnic COPD
ClinicalTrials.gov study NCT03238014. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov study NCT00662740. IPD Sharing: YES. Countries: 18. Publications: 0.
Effects of PNF D2 Technique With Resistance on Pulmonary Function, Exercise Capacity and Health Status of COPD Patients
ClinicalTrials.gov study NCT04534062. IPD Sharing: NO. Countries: 1. Publications: 0.
Study on Pulmonary Rehabilitation for Stable Chronic Obstructive Pulmonary Disease(COPD) Patients
ClinicalTrials.gov study NCT04741373. IPD Sharing: NO. Countries: 1. Publications: 0.
Combined Effects of Transcutaneous Electrical Diaphragmatic Stimulation With ACBT'S in Copd
ClinicalTrials.gov study NCT07079553. IPD Sharing: NO. Countries: 1. Publications: 0.
Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov study NCT01419158. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD
ClinicalTrials.gov study NCT03674320. IPD Sharing: NO. Countries: 1. Publications: 0.
Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD
ClinicalTrials.gov study NCT06135701. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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