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1,610 results for “ratio”
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios [CytoSNP]
GEO Series GSE190390. Homo sapiens. 19 samples. Type: Genome variation profiling by array; SNP genotyping by SNP array.
RNA seq analysis of calcium channel blocker, nifedipine in combination with metformin, MCC950 and anakinra treated Tet2-/- + Boy/J (1:1 ratio, mixed BM cells) transplanted Ob/Ob recipient mice
GEO Series GSE193062. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
SNX18 inhibits melanoma migration by modulating the activation ratio of Cdc42 & RhoA [microarray]
GEO Series GSE120295. Homo sapiens. 6 samples. Type: Expression profiling by array.
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios [Omni2.5]
GEO Series GSE190392. Homo sapiens. 80 samples. Type: Genome variation profiling by array; SNP genotyping by SNP array.
Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis
GEO Series GSE214954. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
FIGURE. Box-and-whisker diagrams of length:width ratios of the investigated strains. in Morphological and phylogenetic relations of members of the genus Coelastrella (Scenedesmaceae, Chlorophyta) from the Ural and Khentii Mountains (Russia, Mongolia)
FIGURE. Box-and-whisker diagrams of length:width ratios of the investigated strains.
Dataset of global gridded monthly crop coefficient, yearly and monthly blue-to-total water footprint ratio, and national unit blue and green water footprints of maize (2000-2021)
<p>The data includes monthly <span><span>crop coefficient</span></span>, yearly and monthly blue-to-total water footprint ratio at a 5 arcminute spatial scale, and the unit water footprint at an annual national (regional) scale of global maize.</p>
Elevated circulatory proline to glutamine ratio (PQR) in Patients with endometriosis revealed by targeted NMR based serum metabolomics
<p>Endometriosis (EM) is a chronic pain condition affecting women in reproductive age and involves the growth of uterine lining (endometrium) outside of the uterus. EM is often associated with altered inflammatory and immune processes and shares some cancer-like characteristics such as activated glutaminolysis. However, preclinical studies suggest mitochondrial dysfunction and decreased energy production in uterine endometriosis tissue. As proline catabolism in mitochondria serve as an important source of energy production and previous transcriptomics studies have demonstrated that there is reduced activity of proline oxidase (POX, a mitochondrial inner-membrane flavoenzyme involved in the catabolic degradation of the proline) due to overexpression of microRNA (known as MiR-23b). Based on this, we hypothesized and demonstrated that circulatory proline to glutamine ratio (PQR) are elevated in the EM patients and may serve as an indicative biomarker to improve the clinical diagnosis of EM. </p>
Elevated circulatory Glycine to Histidine ratio in Preclinical models of Rheumatoid Arthritis: A Targeted NMR-based metabolomics study
<p><strong>Description:</strong> Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes joint inflammation, bone and cartilage destruction, and sometimes disability. The pathophysiology of RA, on the other hand, is multifactorial and, to a significant extent, unknown. Abnormal glycine metabolism is well established pathophysiological feature in RA [1] and the circulatory levels of glycine are largely reported to be elevated in RA [2]. Further, various clinical studies report the decreased circulatory levels of histidine in RA Patients. The low free serum histidine levels have also been found to be associated with disease activity in RA [3]. Other studies reported higher levels of free histidine in the synovial fluid (SF) compared to that in the patient serum samples of RA (considered to be an inflammatory arthritis condition) but SF histidine levels were significantly lower than corresponding results in patients with osteoarthritis (OA, considered to a non-inflammatory arthritis condition) [4]. Therefore, we hypothesized and demonstrated that the circulatory <strong>glycine to histidine ratio (GHR)</strong> is significantly elevated in RA compared to NC (with p-value <0.0001). For this, fifty (N= 50) serum samples obtained from thirty (N=30) normal control rats and twenty (N=20) rat models of rheumatoid arthritis (RA, induced using Complete Freund's adjuvant (CFA) treatment) were analyzed using high-resolution 800 MHz NMR spectrometer. The serum metabolic profiles were measured using standard 1D-<sup>1</sup>H-CPMG NMR experiments and the concentration levels of selected metabolites (glycine and histidine) were estimated using NMR suite of commercial software CHENOMX following the procedure as described previously from our research group [5]. <strong>The mean values (±standard deviation) of circulatory GHR levels in the serum samples of RA and NC rats were found to be 6.65 ± 2.29 and 3.46 ± 0.93, respectively. </strong>We further performed the receiver operating characteristic (ROC) curve analysis and the resulted area under ROC curve value of <strong>0.97 (with 95% confidence interval 0.92-1.0 and p-value <0.0001) suggested that the circulatory GHR levels have significant potential </strong>to serve as a better preclinical indicator of disease activity in RA and may be a reliable clinical biomarker for monitoring the treatment response in such preclinical models.</p> <p> </p> <p><strong>References:</strong></p> <p>[1] Lemon, H.M., Chasen, W.H. and Looney, J.M., 1952. Abnormal glycine metabolism in rheumatoid arthritis. <em>The Journal of clinical investigation</em>, <em>31</em>(11), pp.993-999.</p> <p>[2] Trang, L.E., Fürst, P., Odeback, A.C. and Lövgren, O., 1985. Plasma amino acids in rheumatoid arthritis. <em>Scandinavian journal of rheumatology</em>, <em>14</em>(4), pp.393-402.</p> <p> </p> <p>[3] Gerber, D.A., 1975. Low free serum histidine concentration in rheumatoid arthritis. A measure of disease activity. <em>The Journal of clinical investigation</em>, <em>55</em>(6), pp.1164-1173.</p> <p> </p> <p>[4] Sitton, N. G., Dixon, J. S., Bird, H. A., & Wright, V. (1986). Serum and synovial fluid histidine: a comparison in rheumatoid arthritis and osteoarthritis. <em>Rheumatology international</em>, <em>6</em>(6), 251-254.</p> <p> </p> <p>[5] Umesh Kumar, Abhai Kumar, Smita Singh, Payal Arya, Sandeep Kumar Singh, Rameshwar Nath Chaurasia, Anup Singh, and Dinesh Kumar, “An elaborative NMR based plasma metabolomics study revealed metabolic derangements in patients with Mild Cognitive Impairment: A study on North Indian Population” <strong>Metabolic Brain Disease</strong> (2021) 36, 957–968. (DOI: 10.1007/s11011-021-00700-z)</p>
Influence of FSH/LH Ratio in Controlled Ovarian Stimulation
ClinicalTrials.gov study NCT02994550. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Transcriptome profiling after reducing source-to-sink ratio in tomato plants reveals alterations in source leaf activity
GEO Series GSE201432. Solanum lycopersicum. 9 samples. Type: Expression profiling by high throughput sequencing.
SNX18 inhibits melanoma migration by modulating the activation ratio of Cdc42 & RhoA
GEO Series GSE120029. Homo sapiens. 8 samples. Type: Expression profiling by array.
Optimized adapter:DNA ratios for efficient ChIP-seq library preparation from low input samples
GEO Series GSE71700. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
cyt_aux_balance-Effect of the Auxin/Cytokinin ratio on the transcriptome of stem cells
GEO Series GSE10725. Arabidopsis thaliana. 12 samples. Type: Expression profiling by array.
EScell data, composed of normalized log ratio of the differentiated compared to the undifferentiated at 5 points
GEO Series GSE4687. Mus musculus. 5 samples. Type: Expression profiling by array.
Standardized incidence ratios for developing a primary uveal melanoma following another primary malignancy
<p>Standardized incidence ratios for developing a primary uveal melanoma following another primary malignancy:</p> <ul> <li>For age groups: <ul> <li>younger than 50 years old, <strong>Supplementary table 5</strong></li> <li>patients 50-70 years old, <strong>Supplementary table 6</strong></li> <li>patients older than 70 years old, <strong>Supplementary table 7</strong></li> </ul> </li> <li>in white patients,<strong> Supplementary Table 8</strong></li> </ul> <p> </p>
Standardized incidence Ratios for developing a second malignancy after First Primary Uveal Melanoma
<p>Standardized incidence Ratios for developing a second malignancy after First Primary Uveal Melanoma:</p> <ul> <li>For age groups: <ul> <li>younger than 50 years old, <strong>Supplementary table 1</strong></li> <li>patients 50-70 years old, <strong>Supplementary table 2</strong></li> <li>patients older than 70 years old, <strong>Supplementary table 3</strong></li> </ul> </li> <li>in white patients,<strong> Supplementary table 4.</strong></li> </ul>
Speedy urbanization ratios
<p>TEST</p> <p>Urabization ratios calculated for sampling sites. Calculated for buffers with increasing radii and based upon GRB dataset from Grootschalig Referentie Bestand (AGIV).</p>
BioFINE ATR peak ratio imide_to_benzene
<p>ATR peak ratio imide_to_benzene</p>
Data Set_Urinary Albumin-to-Creatinine Ratio as an Independent Predictor of Long-term Mortality in Atherosclerotic Cardiovascular Disease Patients: A Propensity Score-Matched Study
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.