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Dataset results
145 results for “CT Angiography;”
Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta
ClinicalTrials.gov study NCT05716568. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Cardiac CT Angiography in Patients With Acute Ischemic Stroke
ClinicalTrials.gov study NCT06176872. IPD Sharing: NO. Countries: 0. Publications: 0.
Dataset related to the article: "CT Perfusion Versus Coronary CT Angiography in Patients With Suspected In-Stent Restenosis or CAD Progression"
<p>This record contains raw data related to the article "CT Perfusion Versus Coronary CT</p> <p>Angiography in Patients With Suspected</p> <p>In-Stent Restenosis or CAD Progression"</p> <p>OBJECTIVES The goal of this study was to assess the diagnostic performance of coronary computed tomography</p> <p>angiography (CTA) alone, adenosine-stress myocardial perfusion assessed by computed tomography (CTP) alone, and</p> <p>coronary CTA þ CTP by using a 16-cm Z-axis coverage scanner versus invasive coronary angiography (ICA) and fractional</p> <p>flow reserve (FFR) as the clinical standard.</p> <p>BACKGROUND Diagnostic performance of coronary CTA for in-stent restenosis detection is still challenging. Recently,</p> <p>CTP showed additional diagnostic power over coronary CTA in patients with suspected coronary artery disease. However,</p> <p>few data are available on CTP performance in patients with previous stent implantation.</p> <p>METHODS Consecutive stable patients with previous coronary stenting referred for ICA were enrolled. All patients</p> <p>underwent stress myocardial CTP and rest CTP þ coronary CTA. Invasive FFR was performed during ICA when clinically</p> <p>indicated. The diagnostic rate and diagnostic accuracy of coronary CTA, CTP, and coronary CTA þ CTP were evaluated in</p> <p>stent-, territory-, and patient-based analyses.</p> <p>RESULTS In the 150 enrolled patients (132 men; mean age 65.1 9.1 years), the CTP diagnostic rate was significantly</p> <p>higher than that of coronary CTA in all analyses (territory based [96.7% vs. 91.1%; p < 0.0001] and patient based [96%</p> <p>vs. 68%; p < 0.0001]). When ICA was used as gold standard, CTP diagnostic accuracy was significantly higher than that</p> <p>of coronary CTA in all analyses (territory based [92.1% vs. 85.5%, p < 0.03] and patient based [86.7% vs. 76.7%,</p> <p>p < 0.03]). The concordant coronary CTA þ CTP assessment exhibited the highest diagnostic accuracy values versus ICA</p> <p>(95.8%in the territory-based analysis). The diagnostic accuracy of CTP was significantly higher than that of coronary CTA</p> <p>(75% vs. 30.5%; p < 0.001). The radiation exposure of coronary CTA þ CTP was 4.15 1.5 mSv.</p> <p>CONCLUSIONS In patients with coronary stents, CTP significantly improved the diagnostic rate and accuracy of coronary</p> <p>CTA alone compared with both ICA and invasive FFR as gold standard.</p>
DATASET RELATED TO THE ARTICLE "Interpretability of coronary CT angiography performed with a novel whole-heart coverage high-definition CT scanner in 300 consecutive patients with coronary artery bypass grafts"
<p>This record contains raw data related to the article: Interpretability of coronary CT angiography performed with a novel wholeheart</p> <p>coverage high-definition CT scanner in 300 consecutive patients with</p> <p>coronary artery bypass grafts'</p> <p>Aims: Coronary CT angiography (CCTA) is an accurate non-invasive tool for the evaluation of coronary artery</p> <p>bypass graft (CABG). However, inability to sustain a long breath-hold, high heart rate (HR) and atrial fibrillation</p> <p>may affect image quality. Moreover, radiation exposure is still a matter of some concern. A scanner combining</p> <p>0.23-mm spatial resolution, new iterative reconstruction and fast gantry rotation time has been recently introduced</p> <p>in the clinical field. The aims of our study were to evaluate interpretability, radiation exposure and</p> <p>diagnostic accuracy of CCTA performed with the latest generation of cardiac-CT scanners compared to invasive</p> <p>coronary angiography (ICA) in the assessment of bypass grafts, and non-grafted and post-anastomotic native</p> <p>coronary arteries.</p> <p>Methods and results: We prospectively enrolled 300 patients undergoing clinically indicated CCTA with a 16-cm</p> <p>z-axis coverage, 256-detector rows, and 0.28-sec gantry rotation time scanner. Coronary artery and graft interpretability,</p> <p>image quality and effective dose (ED) were assessed in all patients and diagnostic accuracy was</p> <p>evaluated in a subgroup of 100 patients who underwent ICA.</p> <p>Mean HR during the scan was 69.6 ± 10.8. Sinus rhythm was present in 118 patients with HR < 75 bpm</p> <p>and in 112 patients with HR≥75 bpm, while 70 patients had atrial fibrillation. CABG interpretability was</p> <p>100%. Compared to ICA, CCTA was able to correctly detecting occlusions or significant stenoses of all CABG</p> <p>segments. Overall interpretability of native coronary segments was 95.6%. Sensitivity, specificity, positive</p> <p>predictive value, negative predictive value and accuracy of coronary arteries were 98.3%, 97.4%, 93.1%, 99.3%</p> <p>and 96.5%, respectively. The diagnostic accuracy in a patient based analysis was 95.2%. Mean ED was</p> <p>3.14 ± 1.7 mSv.</p> <p>Conclusions: The novel whole-heart coverage CT scanner allows to evaluating CABG and native coronary arteries</p> <p>with excellent interpretability and low radiation exposure even in the presence of unfavorable heart rhythm.</p>
Data set from Varga A, Di Leo G, Banga PV, Csobay-Novák C, Kolossváry M, Maurovich-Horvat P, Hüttl K. Multidetector CT angiography of the Circle of Willis: association of its variants with carotid artery disease and brain ischemia. Eur Radiol. 2019 Jan;29(1):46-56. doi: 10.1007/s00330-018-5577-x. Epub 2018 Jun 19. PMID: 29922933; PMCID: PMC6291432.
<p>Data set from the article Data set from Varga A, Di Leo G, Banga PV, Csobay-Novák C, Kolossváry M, Maurovich-Horvat P, Hüttl K. Multidetector CT angiography of the Circle of Willis: association of its variants with carotid artery disease and brain ischemia. Eur Radiol. 2019 Jan;29(1):46-56. doi: 10.1007/s00330-018-5577-x. Epub 2018 Jun 19. PMID: 29922933; PMCID: PMC6291432.</p> <p>This is the abstract</p> <p><strong>Purpose: </strong> (1) to estimate the prevalence of Circle of Willis (CoW) variants in patients undergoing carotid endarterectomy, (2) to correlate these variants to controls and (3) cerebral ischemia depicted by computed tomography (CT).</p> <p><strong>Materials and methods: </strong> After Institutional Review Board approval, data of 544 carotid endarterectomy patients (331 males, mean age 69±8 years) and 196 controls (117 males, mean age 66±11 years) who underwent brain CT and carotid CT angiography (CTA) were retrospectively analysed. Two observers independently classified each CoW segment as normal, hypoplastic (diameter <0.8 mm) or non-visualized. Four groups of CoW variants based on the number of hypoplastic/non-visualized segments were correlated with clinical data (ANOVA, χ<sup>2</sup> and multivariate logistic regression analysis). Intra- and inter-observer agreement was estimated using Cohen κ statistics.</p> <p><strong>Results: </strong> High prevalence of CoW variants (97%) and compromised CoW (81%) was observed in the study group and significant difference was found in the distribution of CoW variants compared to controls (p<0.001), internal carotid artery (ICA) stenosis being the only independent predictor of CoW morphology (p<0.001). Significant correlation was found between CoW configuration and brain ischemia in the study group (p=0.002). ICA stenosis of ≥90% was associated to higher rate of ipsilateral A1 hypoplasia/non-visualization (p<0.001). Intra- and inter-observer agreement was from substantial to almost perfect (Cohen κ=0.75-1.0).</p> <p><strong>Conclusion: </strong> Highly variable CoW morphology was demonstrated in patients undergoing endarterectomy compared to controls. Likely compromised CoW in relation to cerebral ischemia was observed in a large cohort of carotid endarterectomy subjects.</p> <p><strong>Key points: </strong> • CoW variant distribution significantly differed in the study and control groups (p<0.001). • ICA stenosis was the only independent predictor of CoW morphology (p<0.001). • Severely compromised CoW configuration showed significant association with brain ischemia (p=0.002).</p>
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Allen Brain Atlas
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International Brain Laboratory public data
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OpenNeuro
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