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632 results for “Cartilage”
raw data - circNR3C2 promote chondrogenic differentiation and cartilage repair of human adipose-derived stem cells via hsa-miR-647/SOX9 pathway
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Contrast solution properties and scan parameters influence the apparent diffusivity of computed tomography contrast agents in articular cartilage
<p>The inability to detect early degenerative changes to the articular cartilage surface that commonly precede bulk osteoarthritic degradation is an obstacle to early disease detection for research or clinical diagnosis. Leveraging a known artifact that blurs tissue boundaries in clinical arthrograms, contrast agent diffusivity can be derived from computed tomography arthrography (CTa) scans. We combined experimental and computational approaches to study protocol variations that may alter the CTa-derived apparent diffusivity. In experimental studies on bovine cartilage explants, we examined how contrast agent dilution and transport direction (absorption vs. desorption) influence the apparent diffusivity of untreated and enzymatically digested cartilage. Using multiphysics simulations, we examined mechanisms underlying experimental observations and the effects of image resolution, scan interval and early scan termination. The apparent diffusivity during absorption decreased with increasing contrast agent concentration by an amount similar to the increase induced by tissue digestion. Models indicated that osmotically induced fluid efflux strongly contributed to the concentration effect. Simulated changes to spatial resolution, scan spacing and total scan time all influenced the apparent diffusivity, indicating the importance of consistent protocols. With careful control of imaging protocols and interpretations guided by transport models, CTa-derived diffusivity offers promise as a biomarker for early degenerative changes.</p>
Figure 6 in The ossified Meckel's cartilage and internal groove in Mesozoic mammaliaforms: implications to origin of the definitive mammalian middle ear
Figure 6. Phylogenetic relationships and distributions of main mammaliaform groups. Search options include: all characters unordered, equally weighted, accelerated transformation, multistate as uncertainty, rooting at tritylodontids, and monophyletic in-group. Numbers at each node represent assigned branch length, bootstrapping value, and Bremer supporting index. Bootstrapping value is obtained by 1000 replications of heuristic searches. Grey dots represent occurrences of genera (McKenna & Bell, 1997) used in the phylogenetic analyses. Grey bars are distributions of higher taxa (McKenna & Bell, 1997) represented by the genera. Character list, sources of data and detailed tree descriptions can be found in Wang et al. (2001).
Figure 2 in The ossified Meckel's cartilage and internal groove in Mesozoic mammaliaforms: implications to origin of the definitive mammalian middle ear
Figure 2. Skulls of Repenomamus. (A) Ventral view of IVPP V12549 (holotype), showing relationship of the ossified Meckel's cartilage (indicated by arrow) with the dentary and the ear region. (B) Ventromedial view of IVPP V12728, showing the displaced OMC (indicated by arrow). Modified from Wang et al. (2001).
Figure 3 in The ossified Meckel's cartilage and internal groove in Mesozoic mammaliaforms: implications to origin of the definitive mammalian middle ear
Figure 3. Stereophotos of the basicranial region of Repenomamus (holotype, IVPP V12549). Modified from Wang et al. (2001).
T2 orientation anisotropy mapping of articular cartilage using qMRI
<p>Data and codes for publication entitled "T2 orientation anisotropy mapping of articular cartilage using qMRI"</p>
Study to Evaluate the Safety and Performance of Treatment of Articular Cartilage Lesions Located on the Femoral Condyle With gelrinC
ClinicalTrials.gov study NCT00989794. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Changes in Knee Articular Cartilage Volume in Women on Aromatase Inhibitors
ClinicalTrials.gov study NCT00111241. IPD Sharing: NO. Countries: 1. Publications: 0.
Autologous Cell-derived Tissue Engineered Cartilage for Repairing Articular Cartilage Lesions
ClinicalTrials.gov study NCT02770209. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial
ClinicalTrials.gov study NCT04210986. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of Safety and Exploratory Efficacy of CARTISTEM®, a Cell Therapy Product for Articular Cartilage Defects
ClinicalTrials.gov study NCT01733186. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Sprifermin (AS902330) in Cartilage Injury Repair (CIR)
ClinicalTrials.gov study NCT01066871. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Assess the Safety of Treatment of Articular Cartilage Lesions With CartiLife®
ClinicalTrials.gov study NCT03517046. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Study to Assess the Efficacy and Safety of Treatment of Articular Cartilage Lesions With CartiLife®
ClinicalTrials.gov study NCT03545269. IPD Sharing: UNDECIDED. Countries: 0. Publications: 2.
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing
ClinicalTrials.gov study NCT06749366. IPD Sharing: YES. Countries: 1. Publications: 0.
Extension Study for Participants of MACI00206 Study of MACI® for the Treatment of Symptomatic Articular Cartilage Defects of the Knee
ClinicalTrials.gov study NCT01251588. IPD Sharing: NO. Countries: 7. Publications: 0.
Value of Adding T2 Mapping Routine MRI in Assessment of Knee Articular Cartilage Early Osteoarthritis
ClinicalTrials.gov study NCT07316257. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.
ClinicalTrials.gov study NCT00793104. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mechanical vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions
ClinicalTrials.gov study NCT01803880. IPD Sharing: Not stated. Countries: 1. Publications: 0.
To Look at the Characteristics of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection
ClinicalTrials.gov study NCT01895959. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.