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351 results for “Case control studies”
Supplementary material 11 from: Moore MR, Talamas EJ, Bremer JS, McGathey N, Fulton JC, Lahey Z, Awad J, Roberts CG, Combee LA (2023) Mining biodiversity databases establishes a global baseline of cosmopolitan Insecta mOTUs: a case study on Platygastroidea (Hymenoptera) with consequences for biological control programs. NeoBiota 88: 169-210. https://doi.org/10.3897/neobiota.88.106326
Summary of intercontinental and island Platygastroidea BINs
Supplementary material 5 from: Moore MR, Talamas EJ, Bremer JS, McGathey N, Fulton JC, Lahey Z, Awad J, Roberts CG, Combee LA (2023) Mining biodiversity databases establishes a global baseline of cosmopolitan Insecta mOTUs: a case study on Platygastroidea (Hymenoptera) with consequences for biological control programs. NeoBiota 88: 169-210. https://doi.org/10.3897/neobiota.88.106326
Platygastroidea COI dataset NJ tree annotated FIGTREE
Supplementary material 1 from: Moore MR, Talamas EJ, Bremer JS, McGathey N, Fulton JC, Lahey Z, Awad J, Roberts CG, Combee LA (2023) Mining biodiversity databases establishes a global baseline of cosmopolitan Insecta mOTUs: a case study on Platygastroidea (Hymenoptera) with consequences for biological control programs. NeoBiota 88: 169-210. https://doi.org/10.3897/neobiota.88.106326
Country to continent and island group assignments
Supplementary material 10 from: Moore MR, Talamas EJ, Bremer JS, McGathey N, Fulton JC, Lahey Z, Awad J, Roberts CG, Combee LA (2023) Mining biodiversity databases establishes a global baseline of cosmopolitan Insecta mOTUs: a case study on Platygastroidea (Hymenoptera) with consequences for biological control programs. NeoBiota 88: 169-210. https://doi.org/10.3897/neobiota.88.106326
Pairwise geographic hit comparisons for the Insecta BIN dataset
Periodontitis and Pre-eclampsia among Pregnant Women in Rwanda: A Case-Control Study.
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How patients with mild dementia living in a nursing home benefit from dementia cafés: a case-control study focusing on psychological and behavioural symptoms and caregiver burden
<p><strong>Background: </strong>Dementia is a syndrome, mainly due to neurodegeneration, affecting cognition, behaviour, feelings and relationships. Pharmacological treatment is still challenging and thus different ways to improve/slow down the disease are necessary.</p> <p><strong>Methods: </strong>Twenty-five subjects with mild dementia, living in a nursing home, and their relatives were invited to attend a dementia cafe, a community group which provides support for families affected by dementia. Each patient was evaluated by a neuropsychologist, through the administration of a specific neuropsychological battery, before and at the end of the study. Their outcomes were compared to a matched group of patients with dementia receiving psycho-counselling.</p> <p><strong>Results: </strong>After the dementia cafe meetings, patients showed higher significant changes in mood (P < 0.01), behavioural symptoms (P < 0.001), quality of life (P < 0.001), and caregiver burden (P < 0.001). The control group significantly improved only in quality of life with a reduction of caregiver burden.</p> <p><strong>Conclusions: </strong>Our findings confirm that patients with dementia may benefit from the dementia cafe, especially concerning behavioural symptoms. Moreover, caregivers find these cafés to be welcoming, relaxed places to socialise and access support and information. Future dementia cafés should create programs and comfortable environments answering to the different needs of the patients.</p>
Phenotypes of painful TMD in discordant monozygotic twins according to a cognitive-behavioral-emotional model: a case-control study
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Data from: Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: a case-control study
Objective: We aimed to determine the association between ruptured saccular aneurysms and aspirin use/aspirin dose. Methods: 4,701 patients who were diagnosed at the Massachusetts General Hospital and Brigham and Women's Hospital between 1990 and 2016 with 6,411 unruptured and ruptured saccular intracranial aneurysms were evaluated. Univariable and multivariable logistic regression analyses were performed to determine the association between aSAH and aspirin use, including aspirin dose. Inverse probability weighting using propensity scores was used to adjust for potential differences in baseline characteristics between cases and controls. Additional analyses were performed to examine the association of aspirin use and re-rupture prior to treatment. Results: In multivariate analysis with propensity score weighting, aspirin use (OR 0.60, 95% CI 0.45-0.80) was significantly associated with decreased risk of ruptured intracranial aneurysms. There was a significant inverse dose-response relationship between aspirin dose and aneurysmal subarachnoid hemorrhage (OR 0.65, 95% CI 0.53-0.81). In contrast, there was a significant association between aspirin use and increased risk of re-rupture prior to treatment (OR 8.15, 95% CI 2.22-30.0). Conclusions: In this large case-control study, aspirin therapy at diagnosis was associated with a significantly decreased risk of subarachnoid hemorrhage, with an inverse dose-response relationship among aspirin users. However, once rupture has occurred, aspirin is associated with an increased risk of re-rupture prior to treatment.
Data from: Mental illness, poverty and stigma in India: a case control study
Objective: To assess the effect of experienced stigma on depth of multidimensional poverty of persons with severe mental illness (PSMI) in Delhi, India, controlling for gender, age and caste. Design: Matching case (hospital)–control (population) study. Setting: University Hospital (cases) and National Capital Region (controls), India. Participants: A case–control study was conducted from November 2011 to June 2012. 647 cases diagnosed with schizophrenia or affective disorders were recruited and 647 individuals of same age, sex and location of residence were matched as controls at a ratio of 1:2:1. Individuals who refused consent or provided incomplete interview were excluded. Main outcome measures: Higher risk of poverty due to stigma among PSMI. Results: 38.5% of PSMI compared with 22.2% of controls were found poor on six dimensions or more. The difference in multidimensional poverty index was 69% between groups with employment and income of the main contributors. Multidimensional poverty was strongly associated with stigma (OR 2.60, 95% CI 1.27 to 5.31), scheduled castes/scheduled tribes/other backward castes (2.39, 1.39 to 4.08), mental illness (2.07, 1.25 to 3.41) and female gender (1.87, 1.36 to 2.58). A significant interaction between stigma, mental illness and gender or caste indicates female PSMI or PSMI from 'lower castes' were more likely to be poor due to stigma than male controls (p<0.001) or controls from other castes (p<0.001). Conclusions: Public stigma and multidimensional poverty linked to SMI are pervasive and intertwined. In particular for low caste and women, it is a strong predictor of poverty. Exclusion from employment linked to negative attitudes and lack of income are the highest contributors to multidimensional poverty, increasing the burden for the family. Mental health professionals need to be aware of and address these issues.
Data from: Can perfusion CT unmask postictal stroke mimics? A case-control study of 133 patients
OBJECTIVE: To study the diagnostic value of volume perfusion CT (VPCT) in patients with transient focal neurological deficits following and during epileptic seizures, that mimic symptoms of stroke. METHODS: a retrospective case-control study was performed on 159 patients that presented with a seizure and received an emergency VPCT within the first 3.5 hours of admission, after being misjudged to have an acute stroke. The reference test was a clinical-based, EEG-supported diagnostic algorithm for seizure. RESULTS: We included 133 patients: 94 stroke-mimicking cases with postictal focal neurological deficits ("Todd's phenomenon", n=67) or ongoing seizure on hospital admission ("ictal patients", n=27), and 39 postictal controls without focal neurological deficits. Patients with Todd's phenomenon showed normal (64%), hypo (21%)- and hyperperfusion (14%) on early VPCT. Ictal patients displayed more hyperperfusion compared to postictal patients (p=0.015). Test sensitivity of hyperperfusion for ictal patients is 38% CI [20.7-57.7], specificity 86% CI [77.3-91.7], positive predictive value (ppv) is 42% CI [27.5-58.7], the negative predictive value (npv) 83% CI [78.6-86.9]. A cortical distribution was seen in all hyperperfusion scans, compared to a cortico-subcortical pattern in hypoperfusion (p<0.001). A history of complex focal seizure and age were associated with hyperperfusion (p= 0.046 and 0.038, respectively). CLASSIFICATION OF EVIDENCE: This study provides Class IV evidence that VPCT accurately differentiates ictal stroke mimics from acute ischemic stroke. CONCLUSION: VPCT can differentiate ictal stroke mimics with hyperperfusion from acute ischemic stroke, but not postictal patients who display perfusion patterns overlapping with ischemic stroke.
Nodding Syndrome, a Case-control Study in Mahenge, Tanzania: Onchocerca volvulus and not Mansonella perstans as Risk Factor
<p><strong>Background</strong>: Nodding syndrome (NS) has been consistently associated with onchocerciasis. Nevertheless, a positive association between NS and a <em>Mansonella perstans</em> infection was found in South Sudan. We aimed to determine whether the latter parasite could be a risk factor for NS in Mahenge.</p> <p><strong>Methods</strong>: Cases of epilepsy were identified in villages affected by NS in Mahenge, Tanzania, and matched with controls without epilepsy of the same sex, age and village. We examined blood films of cases and controls to identify <em>M. perstans</em> infections. The participants were also asked for sociodemographic and epilepsy information, examined for palpable onchocercal nodules and onchocerciasis-related skin lesions and tested for anti-<em>Onchocerca volvulus</em> antibodies (Ov16 IgG4) by ELISA. Clinical characteristics of cases and controls, <em>O. volvulus </em>exposure status and relevant sociodemographic variables were assessed by a conditional logistic regression model for NS and epilepsy status matched for age, sex and village.</p> <p><strong>Results</strong>: A total of 113 epilepsy cases and 132 controls were enrolled, of which, respectively, 56 (49.6%) and 64 (48.5%) were men. The median age in cases and controls was 28.0 (IQR: 22.0–35.0) and 27.0 (IQR: 21.0-33.3) years. Of the persons with epilepsy, 43 (38.1%) met the probable NS criteria and 106 (93.8%) had onchocerciasis-associated epilepsy (OAE). <em>M. perstans</em> infection was absent in all participants, while Ov16 seroprevalence was positively associated with probable NS (odds ratio (OR): 5.05, 95%CI: 1.79–14.27) and overall epilepsy (OR: 2.03, 95%CI: 1-07–3.86). Moreover, onchocerciasis-related skin manifestations were only found in the cases (n = 7, p=0.0040), including persons with probable NS (n=4, p=0.0033). Residing longer in the village and having a family history of seizures were positively correlated with Ov16 status and made persons at higher odds for epilepsy, including</p>
Supplementary material 2 from: Seehausen ML, Branco M, Afonso C, Kenis M (2023) Testing a modified version of the EPPO decision-support scheme for release of classical biological control agents of plant pests using Ganaspis cf. brasiliensis and Cleruchoides noackae as case studies. NeoBiota 87: 121-141. https://doi.org/10.3897/neobiota.87.103187
Assessment of Ganaspis cf. brasiliensis
Supplementary material 3 from: Seehausen ML, Branco M, Afonso C, Kenis M (2023) Testing a modified version of the EPPO decision-support scheme for release of classical biological control agents of plant pests using Ganaspis cf. brasiliensis and Cleruchoides noackae as case studies. NeoBiota 87: 121-141. https://doi.org/10.3897/neobiota.87.103187
Assessment of Cleruchoides noackae
Observational Multicenter Case-control Study to Assess Nailfold Capillary Abnormalities in Systemic Lupus Erythematosus
ClinicalTrials.gov study NCT02801812. IPD Sharing: NO. Countries: 0. Publications: 3.
Metabolomics and Breast Cancer Risk in a Nested Case-control Study of the Cancer Prevention Study-II Nutrition Cohort
ClinicalTrials.gov study NCT03282812. IPD Sharing: UNDECIDED. Countries: 0. Publications: 2.
Seroprevalence of Brucella Antibodies in High-Risk Patients With Low Back Pain: A Case-Control Study
ClinicalTrials.gov study NCT07112677. IPD Sharing: NO. Countries: 1. Publications: 0.
The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute
ClinicalTrials.gov study NCT02808546. IPD Sharing: UNDECIDED. Countries: 0. Publications: 6.
Mammographic Density and the Risk of Tumor Recurrence in Asian Women: a Case-control Study
ClinicalTrials.gov study NCT02771665. IPD Sharing: NO. Countries: 0. Publications: 1.
Finasteride (MK-0906) and Male Breast Cancer - A Register-Based Nested Case-Control Study (MK-0906-162/2003.021).
ClinicalTrials.gov study NCT01703520. IPD Sharing: NO. Countries: 0. Publications: 1.
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
ClinicalTrials.gov study NCT06752486. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.