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183 results for “Conservation genomics”
Data from: Conservation and novelty in the microRNA genomic landscape of hyperdiverse cichlid fishes
MicroRNAs (miRNAs) play crucial roles in the post-transcriptional control of messenger RNA (mRNA). These miRNA-mRNA regulatory networks are present in nearly all organisms and contribute to development, phenotypic divergence, and speciation. To examine the miRNA landscape of cichlid fishes, one of the most species-rich families of vertebrates, we profiled the expression of both miRNA and mRNA in a diverse set of cichlid lineages. Among these, we found that conserved miRNAs differ from recently arisen miRNAs (i.e. lineage specific) in average expression levels, number of target sites, sequence variability, and physical clustering patterns in the genome. Furthermore, conserved miRNA target sites tend to be enriched at the 5' end of protein-coding gene 3'UTRs. Consistent with the presumed regulatory role of miRNAs, we detected more negative correlations between the expression of miRNA-mRNA functional pairs than in random pairings. Finally, we provide evidence that novel miRNA targets sites are enriched in genes involved in protein synthesis pathways. Our results show how conserved and evolutionarily novel miRNAs differ in their contribution of the genomic landscape and highlight their particular evolutionary roles in the adaptive diversification of cichlids.
Comparative genomics of Steinernema reveals deeply conserved gene regulatory networks
GEO Series GSE68588. Caenorhabditis elegans; Steinernema feltiae; Steinernema carpocapsae. 24 samples. Type: Expression profiling by high throughput sequencing.
Genome-Wide Identification and Comprehensive Analysis of Conserved MicroRNAs and Phased small Interfering RNAs in Watermelon [miRNA-Seq]
GEO Series GSE102028. Citrullus lanatus. 14 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Landscape genomics analysis: A comprehensive guide to enhance the conservation and use of plant genetic resources
Open the record for dataset details and reuse information.
Data from: Conservation and novelty in the microRNA genomic landscape of hyperdiverse cichlid fishes
Open the record for dataset details and reuse information.
Conservation genomics reveals pesticide and pathogen exposure in the declining bumblebee Bombus terricola
GEO Series GSE174536. Bombus terricola. 30 samples. Type: Expression profiling by high throughput sequencing.
Genome-resolved metatranscriptomics reveals conserved root colonization determinants in a synthetic microbiota
GEO Series GSE231841. unidentified soil bacteria; Arabidopsis thaliana. 6 samples. Type: Expression profiling by high throughput sequencing.
Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells
GEO Series GSE94936. Danio rerio; Homo sapiens; Gasterosteus aculeatus. 21 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Comprehensive Annotations of Human Herpesvirus 6A and 6B Genomes Reveals Novel and Conserved Genomic Features
GEO Series GSE135363. Human herpesvirus 6 (strain GS); Human herpesvirus 6 strain Z29; Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Other.
Genome-wide analysis of Prz1 in fission yeast reveals a novel inhibitory role in flocculation and a conserved activating role in cell wall organization [ChIP-chip]
GEO Series GSE77760. Schizosaccharomyces pombe. 4 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features.
GEO Series GSE29183. Mus musculus; Drosophila melanogaster. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation
GEO Series GSE72099. Homo sapiens; Ambystoma mexicanum; Xenopus laevis. 24 samples. Type: Expression profiling by array.
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation [human data
GEO Series GSE72098. Homo sapiens. 12 samples. Type: Expression profiling by array.
Genome-wide targets of conserved histone chaperone Asf1 in budding yeast
GEO Series GSE40717. Saccharomyces cerevisiae. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide analysis of Prz1 in fission yeast reveals a novel inhibitory role in flocculation and a conserved activating role in cell wall organization [expression]
GEO Series GSE77759. Schizosaccharomyces pombe. 14 samples. Type: Expression profiling by array.
The conserved histone chaperone Spt6 facilitates DNA replication and mediates genome stability [MCM ChIPseq]
GEO Series GSE221913. Saccharomyces cerevisiae. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation [axolotl da
GEO Series GSE72096. Ambystoma mexicanum. 9 samples. Type: Expression profiling by array.
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation [frog data]
GEO Series GSE72097. Xenopus laevis. 3 samples. Type: Expression profiling by array.
Comparative genomic hybridization of environmental Escherichia coli isolates indicates highly conserved ecophysiology
GEO Series GSE6407. Escherichia coli; Escherichia coli K-12. 10 samples. Type: Genome variation profiling by array.
Conservation genomics and pollination biology of an endangered, edaphic-endemic, octoploid herb: El Dorado bedstraw (Galium californicum subsp. sierrae; Rubiaceae)
<p>Supplementary data.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.