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2,271
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ShareScore release 0.9.0
Dataset results
2,271 results for “Endothelial cells”
Data from: The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes
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Data from: Mosquito saliva increases endothelial permeability in the skin, immune cell migration, and dengue pathogenesis during antibody-dependent enhancement
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Effect of microgravity on HUVECs (Human Umbilical vein Endothelial cells) cells and its transcriptome analysis.
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and formation of space colonies. In this connection cardiovascular adaptation in low gravity is a critical component of human space exploration. Deep high-throughput sequencing approach allowed us to analyze the miRNA and mRNA expression profiles in human umbilical cord vein endothelial cells (HUVEC) cultured under gravity (G) and stimulated microgravity (MG) achieved with a clinostat. The present study identified totally 1870 miRNAs differentially expressed in HUVEC under MG condition when compared to the cells subjected to unitary G conditions. The functional association of identified miRNAs targeting specific mRNAs revealed that miRNAs hsa-mir-496 hsa-mir-151a hsa-miR-296-3p hsa-mir-148a hsa-miR-365b-5p hsa-miR-3687 hsa-mir-454 hsa-miR-155-5p and hsa-miR-145-5p differentially regulated the genes involved in cell adhesion angiogenesis cell cycle JAK-STAT signaling MAPK signaling nitric oxide signaling VEGF signaling and wound healing pathways. Further the q-PCR based experimental studies of upregulated and downregulated miRNA and mRNAs demonstrate that the above reported miRNAs influence the cell proliferation and vascular functions of the HUVEC in MG conditions effectively. Consensus on the interactome results indicates restricted fluctuations in the transcriptome of the HUVEC exposed to short-term MG that could lead to higher levels of endothelial functions like angiogenesis and vascular patterning.
Transcriptional Profiles of Pulmonary Artery Endothelial Cells in Pulmonary Hypertension
GEO Series GSE243193. Homo sapiens. 55 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing on stem cell-derived endothelial cells
GEO Series GSE156009. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Impact of severe traumatic brain injury (TBI) on cerebral blood flow and the endothelial cell phenotype
GEO Series GSE271769. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Silencing KRIT1 Partially Reverses the Effects of Disturbed Flow on the Endothelial Cell Transcriptome
GEO Series GSE288811. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
miR-486-5p inhibits eNOS and angiogenesis in cultured endothelial cells by targeting MAML3
GEO Series GSE281065. Homo sapiens. 6 samples. Type: Other.
Analysis of the human endothelial cell response to Borrelia burgdorferi wild-type and deleted in the gene encoding the integrin ligand P66 [experiment B]
GEO Series GSE27995. Homo sapiens. 16 samples. Type: Expression profiling by array.
Transcriptional changes on lymphatic endothelial cells upon co-culture with human melanoma cells
GEO Series GSE247542. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile at single cell level of endothelial cells (ECs) from the WT and Apoa1bp-/- mice adductors with femoral artery ligation (FAL) injury
GEO Series GSE279901. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Cellular scRNA-seq of human umbilical cord mesenchymal stem cell (HUCMSC) and human umbilical vein endothelial cells (HUVEC)
GEO Series GSE199071. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Molecular atlas of fetal and adult human liver sinusoidal endothelial cells: a F8 secreting cell [methylation III]
GEO Series GSE142224. Homo sapiens. 9 samples. Type: Methylation profiling by high throughput sequencing.
Effects of PAK4 knockdown on gene expression in glioblastoma-associated endothelial cells
GEO Series GSE154133. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of lung endothelial cells in SARS-CoV-2 infection model
GEO Series GSE230022. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
CRISPR/Cas9-mediated suppression of A4GALT rescue endothelial cell dysfunction in a human induced pluripotent stem cell derived fabry disease vasculopathy model
GEO Series GSE241251. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
High-content CRISPR screens link coronary artery disease genes to endothelial cell programs [ChIPseq]
GEO Series GSE210491. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification
GEO Series GSE159694. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Analysis of the human endothelial cell response to pathogenic Leptospira interrogans vs. non-pathogenic Leptospira biflexa (HMEC data)
GEO Series GSE23173. Homo sapiens. 18 samples. Type: Expression profiling by array.
Geometric control of the coronary artery endothelial cell transcriptome following standard growth condition
GEO Series GSE43349. Homo sapiens. 12 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.