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302 results for “Incidence studies”

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dryad24/100

Data from: Ectopic fat obesity presents the greatest risk for incident type 2 diabetes: a population-based longitudinal study

Objectives: Obesity is a risk factor for type 2 diabetes mellitus. Among obesity, visceral fat obesity, and ectopic fat obesity, it has been unclear which has the greatest effect on incident diabetes. Methods: In this historical cohort study of 8430 men and 7034 women, we investigated the effect of obesity phenotypes on incident diabetes. Obesity, visceral fat obesity, and ectopic fat obesity were defined as body mass index ≥25 kg/m2, waist circumference ≥90 cm in men or ≥80 cm in women, and having fatty liver diagnosed by abdominal ultrasonography, respectively. We divided the participants into eight groups according to the presence or absence of the three obesity phenotypes. Results: During the median 5.8 years follow-up for men and 5.1 years follow-up for women, 286 men and 87 women developed diabetes. Compared to the non-obese group, the hazard ratios (HRs) of incident diabetes in the only-obesity, only-visceral fat obesity, only-ectopic fat obesity groups, and with all-three types of obesity group were 1.85 (95%CI 1.06–3.26, p = 0.05) in men and 1.79 (0.24–13.21, p = 0.60) in women, 3.41 (2.51–4.64, p < 0.001) in men and 2.30 (0.87–6.05, p = 0.12) in women, 4.74 (1.91–11.70, p < 0.001) in men and 13.99 (7.23–27.09, p < 0.001) in women and 10.5 (8.02–13.8, p < 0.001) in men and 30.0 (18.0–50.0, p < 0.001) in women. Moreover, the risk of incident diabetes of the groups with ectopic fat obesity were almost higher than that of the four groups without ectopic fat obesity. Conclusion: Ectopic fat obesity presented the greatest risk of incident type 2 diabetes.

opencc-zeroDec 2017View details →

zenodo24/100

Increasing Contribution of Adolescent Type 1 Diabetes Drives Incidence Rates in Poland - a 40-year-long Observational Study

<div> <div> Aims/hypothesis: 40-year-long longitudinal observation of long-term trends of type 1 diabetes incidence and prevalence in children in Central Poland   </div> <div> Methods: This was a prospective observational study performed by a reference regional center for pediatric diabetes care for Lodz Province (currently 2·4M inhabitants, 360K children). We registered each case of new-onset type 1 diabetes admitted to regional pediatric diabetes centers between the years 1983 and 2022 in children between 0 and 14 y.o. The diagnosis was based on currently available guidelines. Cases of other types of diabetes (e.g., monogenic) were excluded upon identification from incidence and prevalence rates. Yearly data on the at-risk population were acquired from Poland`s General Statistical Office. Sex-specific data on population structure were available from 1989 onwards.   </div> <div> Results: In the analyzed period, the incidence rate of type 1 diabetes increased tenfold from 3·29/100,000 (95%CI: 1·85-4·73) in 1983 to 32.43 (26·42-38·44) in 2022, with an average annual percentage change of 5·73% (95%CI: 4·99%-6·44%). Joinpoint analysis detected two distinct periods of increase: rapid in 1983-2005 (annual percentage increase of 7·38%, 95%CI: 6·30-10·52%) and a slower one in 2005-2022 (3·65%, 95%CI: -0·86-5·13%). Incidence rates among the youngest children (0-4 y.o.) were significantly lower than in 5-9 y.o. (β±SE: -0·567±0·059, p<0·0001) and 10-14 y.o. (β±SE: -0·520±0·060, p<0·0001). The incidence growth dynamic for the two older groups showed a consistent increase, whereas the incidence in 0-4 year-olds plateaued after 2007. Incidence rates varied seasonally, with the most cases diagnosed during the winter months (December, January, and February; mean difference from remaining seasons of 29±11·6 percentage points, p<0·0001). Corresponding with increasing incidence rate, estimated prevalence of type 1 diabetes increased over the years and reached 177·21/100,000 (95%CI: 163·18-191·24) for children 0-14 y.o., and  17·11 (95%CI: 9·2-25·02), 190·54 (95%CI: 165·03-215·75), 238·73 (95%CI: 211·7-265·76) for 0-4, 5-9, and 10-14 y.o., respectively.  </div> <div> Conclusion/interpretation: Over the past 40 years, the incidence of type 1 diabetes in children in Central Poland has increased significantly, but the rate of increase appears to be slowing. As majority of patients with type 1 diabetes are 10 years old or older, with the most new cases occurring in that age group the healthcare systems should prepare for care of young adults who are extensive users of new diabetes technologies.  </div> </div>

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Dataset results

Data from: Ectopic fat obesity presents the greatest risk for incident type 2 diabetes: a population-based longitudinal study

Increasing Contribution of Adolescent Type 1 Diabetes Drives Incidence Rates in Poland - a 40-year-long Observational Study

Study of the Incidence and Prognosis of Intrahospital Acute Kidney Injury

Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PN 200 or Naproxen in Subjects Who Are at Risk for Developing NSAID-Associated Ulcers.

The THINK Study Incidence of Neurotrophic Keratopathy)

Incidence of Hoarseness After General Spine Surgery: Prospective Observational Study

Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.

Non-COVID Patient-safety Incidents Reported by Primary Care Professionals in Time of Lockdown: Protocol for a Cross-sectional Descriptive Study

Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels

A Study Utilising Data From European Union (EU) National Multiple Sclerosis (MS) Registries to Assess the Incidence of Anti-Natalizumab Antibody Among Participants Who Receive Subcutaneous Administrat

Cohort Study of HIV-1 Incidence Among Clients of the Thai Red Cross AIDS Research Center, Bangkok, Thailand

Comparison of Environmental Factors Between the Areas of Over- and Under-incidence of Crohn's Disease in the Haut de France Region, by the Study of Dental Exposomes

Does the Thickness of the Gastrostomy Affect the Incidence of Complications? A Prospective Randomized Single-Center Study in Children

Efficacy and Safety Study of Azimilide on the Incidence of Cardiovascular Hospitalizations/Emergency Department Visits or Cardiovascular Death in Patients With an Implantable Cardioverter Defibrillato

Observational Study for the Evaluation of Incidence of Familial AML/MDSs in Patients With Myeloid Neoplasms

Multifactorial Study of the Relationship Between the Conditions of Life and the Incidence of Risk of Falling

An Observational Study to Register the Incidence of Breast Cancer and Current Clinical Care Patterns in Kenya

Study on the Incidence of Delirium in a Respiratory Weaning Centre

Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure

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