Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
16,682
datasets available to search
ShareScore release 0.9.0
Dataset results
16,682 results for “Lung.”
Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots.
ClinicalTrials.gov study NCT00986154. IPD Sharing: YES. Countries: 38. Publications: 8.
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acr
ClinicalTrials.gov study NCT03447769. IPD Sharing: YES. Countries: 41. Publications: 1.
Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)
ClinicalTrials.gov study NCT04656652. IPD Sharing: YES. Countries: 26. Publications: 2.
Pembrolizumab in Patients With Non-Small Cell Lung Cancer and a Performance Status 2
ClinicalTrials.gov study NCT02733159. IPD Sharing: YES. Countries: 1. Publications: 1.
Families-At-risk for Interstitial Lung Disease Study
ClinicalTrials.gov study NCT03641742. IPD Sharing: YES. Countries: 1. Publications: 5.
A Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib
ClinicalTrials.gov study NCT03535740. IPD Sharing: YES. Countries: 15. Publications: 3.
Study of Safety and Efficacy of EGFR-TKI EGF816 in Combination With cMET Inhibitor INC280 in Adult Patients With EGFR Mutated Non Small Cell Lung Cancer.
ClinicalTrials.gov study NCT02335944. IPD Sharing: YES. Countries: 11. Publications: 2.
A Study of Mobocertinib in Japanese Adults With Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT03807778. IPD Sharing: YES. Countries: 1. Publications: 1.
Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)
ClinicalTrials.gov study NCT02414139. IPD Sharing: YES. Countries: 20. Publications: 3.
Efficacy Regarding Renal Function of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant Recipients
ClinicalTrials.gov study NCT01404325. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Vizgen MERFISH files for Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs
Open the record for dataset details and reuse information.
Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs
Open the record for dataset details and reuse information.
Data from: Lungless tadpoles breathe fresh air into hypotheses for tetrapod lung loss and trait regain
Open the record for dataset details and reuse information.
Aberrant basal cell clonal dynamics shape early lung carcinogenesis
Open the record for dataset details and reuse information.
Data from: The impact of long-term azithromycin on antibiotic resistance in HIV-associated chronic lung disease
Open the record for dataset details and reuse information.
Data and Code for: Phospholipase-catalyzed Degradation Drives Domain Morphology and Rheology Transitions in Model Lung Surfactant Monolayers
Open the record for dataset details and reuse information.
The Burden of Reproduction in Lizards: Changes in Respiratory Physiology Associated with Reduced Lung Volume at the Sevilleta National Wildlife Refuge (2007-2008)
Previous morphological work on lizards suggests that the volume of growing eggs may result in a significant decrease in lung volume during gravidity. Iguanid lizard lungs are located within continuous thoracic and abdominal cavities and are highly distensible. Because of their distensible nature and lack of a diaphragm, both naturally occurring and introduced structures within the abdominal and thoracic cavities (i.e. organs, food, eggs) compress them and potentially reduce available lung volume for gas exchange. During reproduction, this decrease comes at a time of increased energetic demands, due to the cost of provisioning eggs and the physical burden of transporting the extra mass before laying. This means that females must increase the oxygen/carbon dioxide exchange with effectively smaller lung capacity than when they are not reproductive. Therefore, the way species compensate for this decrease affects performance, and ultimately the survival of individuals and their offspring.
Figure 29. Lonchaea hackmani, prothorax unfolding during a lunge, still from Film 13 in Diverse mechanisms of feeding and movement in Cyclorrhaphan larvae (Diptera)
Figure 29. Lonchaea hackmani, prothorax unfolding during a lunge, still from Film 13.
Data from: Integrative genomic analysis in African American children with asthma finds 3 novel loci associated with lung function
<p>Bronchodilator drugs are commonly prescribed for treatment and management of obstructive lung function present with diseases such as asthma. Administration of bronchodilator medication can partially or fully restore lung function as measured by pulmonary function tests. The genetics of baseline lung function measures taken prior to bronchodilator medication has been extensively studied, and the genetics of the bronchodilator response itself has received some attention. However, few studies have focused on the genetics of post-bronchodilator lung function. To address this gap, we analyzed lung function phenotypes in 1,103 subjects from the Study of African Americans, Asthma, Genes, and Environment (SAGE), a pediatric asthma case-control cohort, using an integrative genomic analysis approach that combined genotype, locus-specific genetic ancestry, and functional annotation information. We integrated genome-wide association study (GWAS) results with an admixture mapping scan of three pulmonary function tests (FEV1, FVC, and FEV1/FVC) taken before and after albuterol bronchodilator administration on the same subjects, yielding six traits. We identified 18 GWAS loci, and 5 additional loci from admixture mapping, spanning several known and novel lung function candidate genes. Most loci identified via admixture mapping exhibited wide variation in minor allele frequency across genotyped global populations. Functional fine-mapping revealed an enrichment of epigenetic annotations from peripheral blood mononuclear cells, fetal lung tissue, and lung fibroblasts. Our results point to three novel potential genetic drivers of pre- and post-bronchodilator lung function: ADAMTS1, RAD54B, and EGLN3. </p>
Data set for 'Lunge filter feeding biomechanics constrain rorqual foraging ecology across scale'...
<p>Fundamental scaling relationships influence the physiology of vital rates, which in turn shape the ecology and evolution of organisms. For diving mammals, benefits conferred by large body size include reduced transport costs and enhanced breath-holding capacity, thereby increasing overall foraging efficiency. Rorqual whales feed by engulfing a large mass of prey-laden water at high speed and filter it through baleen plates. However, as engulfment capacity increases with body length across species (Engulfment Volume ∝ Body Length <sup>3.57</sup>), the surface area of the baleen filter does not increase proportionally (Baleen Area ∝ Body Length<sup>1.82</sup>), and thus the filtration time of larger rorquals predictably increases because the baleen surface area must filter a disproportionally large amount of water. We predicted that filtration time should scale with body length to the power of 1.75 (Filter Time ∝ Body Length<sup>1.75</sup><i>)</i>. We tested this hypothesis on four rorqual species using multi-sensor tags with corresponding unoccupied aerial systems (UAS) -based body length estimates. We found that filter time scales with body length to the power of 1.79 (95% CI: 1.61 - 1.97). This result highlights a scale-dependent trade-off between engulfment capacity and baleen area that creates a biomechanical constraint to foraging through increased filtration time. Consequently, larger whales must target high density prey patches commensurate to the gulp size to meet their increased energetic demands. If these optimal patches are absent, larger rorquals may experience reduced foraging efficiency compared to smaller whales if they do not match engulfment capacity to the size of targeted prey aggregations.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.