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Dataset results
162 results for “immune infiltrates”
A very low carbohydrate, ketogenic diet suppresses tumor insulin signaling and enhances immune infiltration in women with endometrial cancer: results from a randomized feasibility study.
GEO Series GSE306395. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
scRNA-seq of B16F10 infiltrating CD45+ immune cells from Kcnj2f/f and Kcnj2CKO mice
GEO Series GSE183783. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
miR-155 plays selective cell-intrinsic roles in brain infiltrating immune cell populations during neuroinflammation
GEO Series GSE206056. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast Cancer
GEO Series GSE278301. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
SOAT1 knockout reshapes tumor immune microenvironment with enhanced CD8+ T cell infiltration and effector function [scRNA-seq]
GEO Series GSE280149. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Single Cell Sequencing Analysis of Infiltrating Immune Cells in Orthotopically Implanted Liver Cancer in Mice Treated with Isotype or Anti-PD-1 Therapy
GEO Series GSE232023. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
scRNA-seq comparison of B16-GP33 tumor-infiltrating immune cells from IgG, anti-PD-1, anti-PSGL-1, or combination anti-PD-1 and anti-PSGL-1 treated mice
GEO Series GSE196112. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
CSN3 promotes gastric cancer invasion and is associated with immune infiltration via activating NOD/TLR pathways
GEO Series GSE317661. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Caspase-1-licensed lung epithelial cell pyroptosis drives infiltrating neutrophil necroptosis to dampen immune defense against pulmonary bacterial infection
GEO Series GSE242879. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Expansion of Tumor-Infiltrating CD8+ T Cell Clonotypes Occurs in the Spleen in Response to Immune Checkpoint Blockade
GEO Series GSE270050. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing; Other.
Prostaglandin E2-EP4 signaling shapes immunosuppressive tumor microenvironment in human tumors by suppressing bioenergetics and ribosome biogenesis in infiltrating immune cells [scRNA-seq]
GEO Series GSE242271. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Immune infiltrating cells in duodenal cancers"
<p>This record contains data related to article "Immune infiltrating cells in duodenal cancers"</p> <p> </p> <p>Abstract.</p> <p> Background: Duodenal adenocarcinoma (DA) is a rare yet aggressive malignancy, with increasing incidence in the</p> <p>last decades. Its low frequency has hampered a thorough understanding of the pathogenesis of the disease and of</p> <p>its biology, limiting the identification of tailored therapeutic options. A large body of evidence has clearly shown the</p> <p>clinical relevance of immune cells in solid tumors, correlating immune features with post-surgical prognosis. The aim</p> <p>of this study was to analyze the immune contexture in a cohort of duodenal adenocarcinomas surgically resected at</p> <p>our Institution and define its correlation with clinical variables.</p> <p> Methods: Tissue slides from paraffin-embedded tumor specimens of 15 consecutive DA and 3 adenomas that</p> <p>underwent a pancreaticoduodenectomy in our center between 2010 to 2018 were immunohistochemically stained.</p> <p>The density (percentage of immune reactive area, IRA%) of immune markers CD45RO, CD8, CD20, IL-17, PD-1, CD68</p> <p>was quantified by computer-assisted image analysis. Demographic, clinical, histopathological data were collected.</p> <p> Results: In our population, median IRA % (IQR) of immune subsets was respectively CD45RO-TILs 2.19 (2.14), CD8-TIL</p> <p>0.42 (0.81), CD20-TILs 0.22 (0.51), CD20-TLT 2.84 (4.64), CD68-TAM 2.19 (1.56), IL17+</p> <p>cells 0.39 (0.39), PD1-TILs 0.19 (0.41).</p> <p>The median follow-up was 47.5 (22.4–63.3) months. At statistical analysis, the density of CD8-TILs inversely correlated</p> <p>with lymph node ratio (p = 0.013), number of metastatic lymph nodes (p = 0.019), and was lower in N+ adenocarcinomas</p> <p>compared to N0 (1.07 vs 0.29; p = 0.093), albeit not significantly. Stratifying patients for the N status, the density of</p> <p>CD8-TILs decreased with the increasing of the N stage (p = 0.065) and was lower in patients who experienced recurrence</p> <p>and died for the disease (0.276 vs 0.641; p = 0.044). Notably, also CD68-TAM distribution was different in patients</p> <p>who had recurrence versus patients who did not (1.028 vs 2.276; p = 0.036).</p> <p> Conclusions: Immune cells showed variable expression in correlation with common prognostic factors, suggesting</p> <p>T cell infiltration may play a protective role towards lymphatic spread of disease and nodal metastatization. Furthermore,</p> <p>T cell density and macrophage infiltration were associated to a lower risk of recurrence and disease related</p> <p>death. A multicentric approach may be indicated to allow analysis of larger cohorts of patients, potentially increasing</p> <p>the power of our observations.</p>
Single-cell RNA sequencing reveals CD74high CCL5high retinal microglia initiating immune cells infiltration in autoimmune uveoretinitis
GEO Series GSE191260. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Quantification of tumour-infiltrating immune cells through deconvolution of DNA methylation data in Ewing sarcomas
GEO Series GSE276012. Homo sapiens. 32 samples. Type: Methylation profiling by array.
Characterization of immune cells infiltrating pancreatic islets using scRNA-seq
GEO Series GSE125455. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Immune infiltration characteristic of colorectal cancer with high and low immune score.
GEO Series GSE271172. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors
GEO Series GSE111201. Homo sapiens; Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
TGFβ inhibition during radiation therapy enhances immune cell infiltration and decreases metastases in a novel humanized mouse model Ewing sarcoma.
GEO Series GSE261693. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Prognostic Significance of Immune Cell Infiltration in Muscle Invasive Bladder Cancer Treated with Definitive Chemoradiation: A Secondary Analysis of RTOG 0524 and 0712
GEO Series GSE245748. Homo sapiens. 73 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptomics reveals species-dependent immune infiltration of T cells in Huntington's disease neurodegeneration
GEO Series GSE254278. Sus scrofa. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.