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7,228 results for “modules”
Pathogen prevalence modulates medication behavior in ant Formica fusca
<p><span>Ants face unique challenges regarding pathogens, as the sociality which has allowed them to form large and complex colonies also raises the potential for transmission of disease within these colonies. To cope with the threat of pathogens, ants have developed a variety of behavioral and physiological strategies. One of these strategies is self-medication, in which animals use biologically active compounds to combat pathogens in a way which would be harmful in the absence of them. <em>Formica fusca</em> ants are to date the only species of ants proven to successfully self-medicate against an active infection caused by a fungal pathogen by supplementing their diet with food containing hydrogen peroxide. Here, we build on that research by investigating how the prevalence of disease in colonies of <em>F. fusca</em> affects the strength of the self-medication response. We exposed either half of the workers of each colony or all of them to a fungal pathogen and offered them different combinations of diets. We see that workers of <em>F. fusca</em> engage in self-medication behavior even if exposed to a low lethal dose of a pathogen, and that the strength of that response is affected by the prevalence of the disease in the colonies. We also saw that the infection status of the individual foragers did not significantly affect their decision to forage on either control food or medicinal food as uninfected workers were also foraging on hydrogen peroxide food, which opens up the possibility of kin medication in partially infected colonies. Our results further affirm the ability of ants to self-medicate against fungal pathogens, shed new light on plasticity of self-medication and raise new questions to be investigated on the role self-medication has in social immunity.</span></p>
Tidally modulated temperature observed atop a drillsite at the Noho hydrothermal site, mid-Okinawa Trough
<p>These are the dataset used in a manuscript submitted to J. Geophys. Res. (AGU), entitled "Tidally modulated temperature observed atop a drillsite at the Noho hydrothermal site, mid-Okinawa Trough" by Kinoshita, M, K. Kitada and T. Nozaki. It is in revision as of June 10 2022. </p> <p>The authors of this dataset include those who organized or participated the expeditions and contributed to obtain the data shown here.</p> <p><strong>Abstract</strong></p> <p>We observed temperature variations over 10 months within a Kuroko ore (hydrothermal sulfide) cultivation apparatus installed atop a 50-m-deep borehole drilled in the Noho hydrothermal system in the mid-Okinawa Trough, southwestern Japan, for monitoring of hydrothermal fluids and in situ mineral precipitation experiments. Temperature and pressure in the apparatus fluctuated with the tidal period immediately after its installation. Initially, the average temperature was 75–76 °C and the amplitude of the semi-diurnal tidal temperature modulation was ~0.3 °C. Four months later, the amplitude of tidal temperature modulation had gradually increased to 4 °C in synchrony with an average temperature decrease to ~40 °C. Numerical modeling showed that both the increase in tidal amplitude and the decrease in average temperature were attributable to a gradual decrease in inflow to the apparatus, which promoted conductive cooling through the pipe wall. The reduced inflow was probably caused by clogging inside the apparatus, but we cannot rule out a natural cause, because the drilling would have significantly decreased the volume of hot fluid in the reservoir. The temperature fluctuation phase lagged the pressure fluctuation phase by ~150°. Assuming that the fluctuations originated from inflow from the reservoir, we conducted 2-D numerical hydrothermal modeling for a poroelastic medium. To generate the 150° phase lag, the permeability in the reservoir needed to exceed that in the ambient formation by ~3 orders of magnitude. The tidal variation phase can be a useful tool for assessing the hydrological state and response of a hydrothermal system. </p> <p><strong>Key Points</strong></p> <ul> <li> <p>Temperature and pressure atop a borehole in the mid-Okinawa Trough hydrothermal system fluctuated with the tidal period during 10 months. </p> </li> <li> <p>The temperature tidal fluctuation phase lagged pressure by ~150° likely because of the poroelastic response of higher permeability sediment. </p> </li> </ul> <ul> <li> <p>A gradual temperature decrease and tidal amplitude increase were caused by reduced inflows that promoted conductive cooling. </p> </li> </ul> <p><strong>Explanation of the dataset</strong></p> <p>*Fig.3_rawdata_C9017B_Long.txt:<br> *Fig.3_rawdata_C9017B_Short:<br> Temperature and pressure data recorded by the probes in the cell (Fig.3_rawdata_C9017B_Long) and the bottom inflow pipe (Fig.3_rawdata_C9017B_Short) during the whole observation period. All dates and times are Japanese Standard Time (JST: UTC+9).</p> <p>*Fig.5_Fig.8_Tidal-height_naotestj_C9017B_JST.txt: <br> Theoretical tidal height at the borehole C9017B, calculated using NAOTIDE program (Matsumoto, K., Takanezawa, T., & Ooe, M. (2000), Ocean tide models developed by assimilating TOPEX/POSEIDON altimeter data into hydrodynamical model: A global model and a regional model around Japan, J. Oceanography, 56, 567-581. https://doi.org/10.1023/A:1011157212596).</p> <p>*Fig.7_Flow-rate.txt: Flow velocity data and the sinusoidal fit during the period immediately after deployment of the apparatus, measured within the inflow pipe of the apparatus.</p> <p><em><strong>Terms of use:</strong></em> These data are provided "as is", without any warranties of any kind. The data are provided under the Creative Commons Attribution 4.0 International license.</p> <p> </p>
Polifonia Corpus - Pilots Module (Meetups) Metadata
<p>We release the Metadata of the Pilots module of the Polifonia Textual Corpus. According to the availability from the source origin, the Metadata may include the URL from which a text of the Pilots corpus is accessible, along with the title, the author, the year of publication, and the publisher. Metadata allows for a complete reconstruction of the corpus as we cannot make the actual texts available because they are subject to heterogeneous licensing.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Pilots Module (Organs) Metadata
<p>We release the Metadata of the Pilots module of the Polifonia Textual Corpus. According to the availability from the source origin, the Metadata may include the URL from which a text of the Pilots corpus is accessible, along with the title, the author, the year of publication, and the publisher. Metadata allows for a complete reconstruction of the corpus as we cannot make the actual texts available because they are subject to heterogeneous licensing.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Pilots Module (Child) Metadata
<p>We release the Metadata of the Pilots module of the Polifonia Textual Corpus. According to the availability from the source origin, the Metadata may include the URL from which a text of the Pilots corpus is accessible, along with the title, the author, the year of publication, and the publisher. Metadata allows for a complete reconstruction of the corpus as we cannot make the actual texts available because they are subject to heterogeneous licensing.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Pilots Module (Bells) Metadata
<p>We release the Metadata of the Pilots module of the Polifonia Textual Corpus. According to the availability from the source origin, the Metadata may include the URL from which a text of the Pilots corpus is accessible, along with the title, the author, the year of publication, and the publisher. Metadata allows for a complete reconstruction of the corpus as we cannot make the actual texts available because they are subject to heterogeneous licensing.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Encyclopedic Module Metadata - Italian Language
<p>We make available the Metadata related to the Wikipedia pages that constitute the Encyclopedic Module of the Polifonia Textual Corpus. Metadata for this module includes, per each Wikipedia page, its Wikipedia ID, BabelNet ID, gloss, resource type (that can be named entity or concept), Lemmata, Sensekey, WikiData ID.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Encyclopedic Module Metadata - French Language
<p>We make available the Metadata related to the Wikipedia pages that constitute the Encyclopedic Module of the Polifonia Textual Corpus. Metadata for this module includes, per each Wikipedia page, its Wikipedia ID, BabelNet ID, gloss, resource type (that can be named entity or concept), Lemmata, Sensekey, WikiData ID.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Encyclopedic Module Metadata - English Language
<p>We make available the Metadata related to the Wikipedia pages that constitute the Encyclopedic Module of the Polifonia Textual Corpus. Metadata for this module includes, per each Wikipedia page, its Wikipedia ID, BabelNet ID, gloss, resource type (that can be named entity or concept), Lemmata, Sensekey, WikiData ID.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Encyclopedic Module Metadata - Dutch Language
<p>We make available the Metadata related to the Wikipedia pages that constitute the Encyclopedic Module of the Polifonia Textual Corpus. Metadata for this module includes, per each Wikipedia page, its Wikipedia ID, BabelNet ID, gloss, resource type (that can be named entity or concept), Lemmata, Sensekey, WikiData ID.</p> <p>Full description at <a href="http://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Polifonia Corpus - Encyclopedic Module Metadata - German Language
<p>We make available the Metadata related to the Wikipedia pages that constitute the Encyclopedic Module of the Polifonia Textual Corpus. Metadata for this module includes, per each Wikipedia page, its Wikipedia ID, BabelNet ID, gloss, resource type (that can be named entity or concept), Lemmata, Sensekey, WikiData ID.</p> <p>Full description at <a href="http://Full description at https://github.com/polifonia-project/Polifonia-Corpus">https://github.com/polifonia-project/Polifonia-Corpus</a></p>
Identification of potential modulators of IFITM3 by in-silico modeling and virtual screening
<p>Modeled structure of IFITM3 and Desmond MD trajectory files for IFITM3 and IFITM3-ligand complexes. Please see README file.</p>
Intratumoural heterogeneity and immune modulation in lung adenocarcinoma of female smokers and never smokers
<p>Count matrix and associated meta data for single nucleus transcriptomics of healthy and tumour lung tissue from lung adenocarcinoma patients. Cohort includes young and elderly, female and male, smokers and never smokers.</p>
Raw data for "Fluorescence crosstalk reduction by modulated excitation-synchronous acquisition for multispectral analysis in high-throughput droplet microfluidics."
<p>Raw data to quantify the crosstalk reduction and signal resolution improvement by MESA used in Figure 3 and 4.</p> <p><br> </p>
Complex plant quality - microbiota - population interactions modulate the response of a specialist herbivore to the defense of its host plant.
<p>1. Many specialist herbivores have evolved strategies to cope with plant defenses, with gut microbiota potentially participating to such adaptations.</p> <p>2. In this study we assessed whether the history of plant use (population origin) and microbiota may interact with plant defense adaptation.</p> <p>3. We tested whether microbiota enhance the performance of <em>Melitaea cinxia </em>larvae on their host plant, <em>Plantago lanceolata</em> and increase their ability to cope the defensive compounds, iridoid glycosides (IGs).</p> <p>3. The gut microbiota was significantly affected by both larval population origin and host plant IG level. Contrary to our prediction, impoverishing the microbiota with antibiotic treatment did not reduce larval performance.</p> <p>5. As expected for this specialized insect herbivore, sequestration of one of IGs was higher in larvae fed with plants producing higher concentration of IGs. These larvae also showed metabolic signature of intoxication (<em>i.e. </em>decrease in Lysine levels). However, intoxication on highly defended plants was only observed when larvae with history of poorly defended plants were simultaneously treated with antibiotics.</p> <p>6. Our results suggest that both adaptation and microbiota contribute to the metabolic response of herbivores to plant defense though complex interactions.</p>
DNA-stimulated liquid-liquid phase separation by eukaryotic topoisomerase II modulates catalytic function
<p>Type II topoisomerases modulate chromosome supercoiling, condensation, and catenation by moving one double-stranded DNA segment through a transient break in a second duplex. How DNA strands are chosen and selectively passed to yield appropriate topological outcomes – e.g., decatenation vs. catenation – is poorly understood. Here we show that at physiological enzyme concentrations, eukaryotic type IIA topoisomerases (topo IIs) readily coalesce into condensed bodies. DNA stimulates condensation and fluidizes these assemblies to impart liquid-like behavior. Condensation induces both budding yeast and human topo IIs to switch from DNA unlinking to active DNA catenation, and depends on an unstructured C-terminal region, the loss of which leads to high levels of knotting and reduced catenation. Our findings establish that local protein concentration and phase separation can regulate how topo II creates or dissolves DNA links, behaviors that can account for the varied roles of the enzyme in supporting transcription, replication, and chromosome compaction.</p>
Subglacial hydrology modulates basal sliding response of the Antarctic ice sheet to climate forcing
<p><strong><em>Kazmierczak22_data.zip</em></strong><strong> contains the </strong><strong>dataset for the publication </strong><strong>« </strong>Subglacial hydrology modulates basal sliding response of the Antarctic ice sheet to climate forcing » <strong>and </strong><strong>the <em>MATLAB</em> codes used to create the figures appearing in the paper. For more details, please, open the <em>Read me.txt</em> file. </strong></p>
Level 3 data in support of Modulation of Bubble Mediated Gas Transfer due to Wave-Current Interactions
<p>WaveWatchIII data output from solutions of a nested configuration off the coast of California. These data are a subset of the solutions reported by Romero et al. 2020.</p> <p>These data are Level 3 of the nested configuration with a horizontal resolution of 120 m.</p> <p>Data are in Netcdf format including the metadata.</p> <p>The simulation period December 2006</p> <p>List of files:</p> <p>L2_Dec2006.nc -- December control solution only forced by winds</p> <p>L2_cew_Dec2006.nc -- December solution including forcing by both winds and currents</p> <p>Grid files can be found at: https://doi.org/10.5281/zenodo.7140916</p>
Level 2 Spring data in support of Modulation of Bubble Mediated Gas Transfer due to Wave-Current Interactions
<p>WaveWatchIII data output from solutions of a nested configuration off the coast of California. These data are a subset of the solutions reported by Romero et al. 2020.</p> <p>These data are Level 2 of the nested configuration with a horizontal resolution of 270 m.</p> <p>Data are in Netcdf format including the metadata.</p> <p>The two simulation periods are December 2006 and Spring 2007.</p> <p>List of files:</p> <p>L2_Mar2007.nc -- Spring control solution only forced by winds</p> <p>L2_cew_Mar2007.nc --- Spring solution including forcing by both winds and currents.</p> <p>Grid files can be found at: https://doi.org/10.5281/zenodo.7140916</p> <p> </p> <p> </p> <p> </p>
Dataset and scripts from: Dietary sterol availability modulates heat tolerance of Daphnia
<p><span>The increasing frequency and intensity of summer heat waves is pushing freshwater zooplankton towards their upper thermal tolerance limits. At the same time, higher temperatures and prolonged water column stratification can favor the dominance of cyanobacteria in phytoplankton. Even when not toxic or grazing resistant, these prokaryotes lack phytosterols as essential precursors for cholesterol, the main sterol in animal tissues. Cholesterol plays a crucial role in the physiological adaptation of ectotherms to high temperature. Therefore, the shift to cyanobacteria-dominated systems may increase the vulnerability of zooplankton to heatwaves by intensifying cholesterol limitation.</span><span> </span><span>Here, we used death time curves that take into consideration the intensity and duration of a thermal challenge and a dynamic model to study the effects of cholesterol limitation on the heat tolerance of the keystone species Daphnia magna and to simulate the cumulative mortality that could occur in a fluctuating environment over several days of heatwave. </span><span> </span><span>We show that increasing cholesterol limitation does not affect the slope between time-to-immobilization and temperature, but does decrease the maximal temperature that Daphnia can withstand by up to 0.74°C. This seemingly small difference is sufficient to halve the time individuals can survive heat stress. </span><span> </span><span>Our simulations predicted that, when facing heatwaves over several days, the differences in survival caused by cholesterol limitation build up rapidly. Considering the anticipated intensity and duration of future (2070-2099) heatwaves, cholesterol limitation could increase mortality</span><span> by up to 45% and 72% under low- and medium-greenhouse-gas-emission scenarios, respectively. </span><span>These results suggest that the increasing risk of cholesterol limitation due to more frequent cyanobacterial blooms could compromise the resistance of zooplankton populations to future heatwaves. More generally,</span><span> this study shows the importance of considering the nutritional context in any attempt to predict ectotherm mortality with increasing temperatures in the field.</span></p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.