Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,774
datasets available to search
ShareScore release 0.9.0
Dataset results
2,774 results for “Agent”
Figure 2 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 2 2D Chemical structure of quercetin (a), 3D chemical structure of quercetin (b).
Figure 9 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 9 Tyrosinase inhibition (%) curve of moringa leaves extract.
Figure 8 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 8 Tyrosinase inhibition (%) curve of kojic acid.
Scheme 3 from: Chaban T, Ogurtsov V, Chaban I, Myrko I, Harkov S, Lelyukh M (2019) Synthesis of some new 4-iminothiazolidine-2-ones as possible antioxidants agents. Pharmacia 66(1): 27-32. https://doi.org/10.3897/pharmacia.66.e35131
Scheme 3 Synthesis of 5-aryliden derivatives 3-phenyl-4-iminothiazolidine-2-one (2a-i).
Scheme 1 from: Chaban T, Ogurtsov V, Chaban I, Myrko I, Harkov S, Lelyukh M (2019) Synthesis of some new 4-iminothiazolidine-2-ones as possible antioxidants agents. Pharmacia 66(1): 27-32. https://doi.org/10.3897/pharmacia.66.e35131
Scheme 1 Synthesis of 3-aryl-4-imino-thiazolidine-2-ones (1a-d).
Scheme 2 from: Chaban T, Ogurtsov V, Chaban I, Myrko I, Harkov S, Lelyukh M (2019) Synthesis of some new 4-iminothiazolidine-2-ones as possible antioxidants agents. Pharmacia 66(1): 27-32. https://doi.org/10.3897/pharmacia.66.e35131
Scheme 2 Hydrolysis to the known 3-aryl-thiazolidine-2,4-diones.
The role of hemostatic agents following dental extractions: a systematic review and meta-analysis
<p class="MsoNormal"><span><strong>Objective: </strong>This study critically evaluated the role of hemostatic agents following dental extractions, and the benefits they add over conventional hemostatic measures.</span></p> <p class="MsoNormal"><span><strong>Materials and methods: </strong>a literature search was conducted, including publications that fulfilled the criteria <span>developed based on the PICOS guidelines; </span><span>Population: <span>patients who receive simple or surgical tooth extractions</span>, </span><span>Intervention: the use of hemostatic agents following dental extraction, </span><span>Control: </span><span>any type of conventional hemostatic measures (i.e. suture, gauze pressure)</span><span>, </span><span>Outcome: </span><span>time to achieve hemostasis following tooth removal, postoperative pain, swelling, or bleeding events, </span><span>and Study design: randomized/controlled clinical trials.</span></span></p> <p class="MsoNormal"><span><strong>Results:</strong> Twenty-eight articles met the inclusion criteria, and 24 were meta-analyzed. Several types of hemostatic agents were used, namely <span>tissue adhesives made from cyanoacrylate or fibrin, tranexamic acid, hemocoagulase</span>, <span>collagen membrane</span>, <span>HemCon dental dressing, epsilon aminocaproic acid</span>, <span>Surgicel</span>, <span>sponges or plugs composed of gelatin</span>, <span>oxidized cellulose</span>, <span>and fibrin</span>. <span>Newer hemostatic agents were also applied, such as Ankaferd blood stopper,</span> <span>and feracrylum</span>. Hemostatic agents demonstrated significantly shorter time to achieve hemostasis and fewer bleeding events in patients on antithrombotic drugs or with bleeding disorders<span> (WMD= -2.12, 95% CI -2.63 to -1.61, P < 0.00001, and RR </span><span>0.61, 95% CI 0.43 to 0.86; P= 0.005, respectively). Furthermore, the use of these agents resulted in significantly less postoperative pain following 3<sup>rd</sup> molar surgery in healthy patients (</span><span>WMD= -</span>0.33<span>, 95% CI </span>-0.65 to -0.02<span>, P = 0.04). Conversely, they did not have any effect on postoperative swelling (WMD= </span>-0.11<span>, 95% CI </span>-0.31 to 0.08<span>, </span>P = 0.26<span>). The time needed to finish the surgical procedure when hemostatic agents were used was shorter but with no significant difference </span>(MD= -78.93, 95% CI -187.35 to 29.49, P = 0.15).</span></p> <p class="MsoNormal"><span><strong>Conclusion: </strong>Included studies differ in their methods of reporting bleeding, pain, and swelling. Thus, the results of this article should be confirmed in future research. Within these limitations, it is concluded that hemostatic agents lead to faster hemostasis and fewer postoperative bleeding incidences, compared to conventional hemostatic measures. Their use is highly recommended following dental extractions in patients on antithrombotic drugs or with bleeding disorders, who are likely to develop postoperative hemorrhage events.</span></p>
Figure 7 in Potential neuroprotective of trans-resveratrol a promising agent tempeh and soybean seed coats-derived against beta-amyloid neurotoxicity on primary culture of nerve cells induced by 2-methoxyethanol
Figure 7. Treatment Group with resveratrol tempeh after induced by Beta-Amyloid (10 x10).
Figure 4 in Potential neuroprotective of trans-resveratrol a promising agent tempeh and soybean seed coats-derived against beta-amyloid neurotoxicity on primary culture of nerve cells induced by 2-methoxyethanol
Figure 4. Treatment group: 2- ME + Resveratrol isolated from Soybean seed coat (10 x10).
Data Statement: Functionalization of Magnetotactic Bacteria with Gold Nanoprisms. A Route to Novel Photothermal Agents.
<p>Data for this article, including UV-vis spectra, heating curves, ICP analysis and optical density measurements</p>
uGIM: week monitorization data of a microgrid with five agents (10/04/19-16/04/19)
<p>uGIM is a microgrid intelligent management software that can represent individual microgrid’s players using a multi-agent approach. This dataset has data regarding a week (from 10-04-2019 to 16-04-2019) of a microgrid with five players (all offices). All agents have consumption and generation data. One of the agents also has sensor data, such as temperature, movement and humidity.</p> <p>In uGIM, agents are deployed in the player’s facilities using single-board computers. All the data in this dataset is read and stored in five single-board computers. Each agent integrates several resources. In this microgrid deployment, all resources use TCP/IP communication. However, uGIM supports more protocols, such as Modbus/RTU and Modbus/TCP.</p> <p>uGIM related publications:<br> - Gomes, L., Vale, Z., & Corchado, J. M. (2020). Microgrid management system based on a multi-agent approach: An office building pilot. Measurement: Journal of the International Measurement Confederation, 154. <a href="http://doi.org/10.1016/j.measurement.2019.107427">https://doi.org/10.1016/j.measurement.2019.107427</a><br> - Gomes, L., Vale, Z. A., & Corchado, J. M. (2020). Multi-Agent Microgrid Management System for Single-Board Computers: A Case Study on Peer-to-Peer Energy Trading. IEEE Access, 8, 64169–64183. <a href="http://doi.org/10.1109/ACCESS.2020.2985254">https://doi.org/10.1109/ACCESS.2020.2985254</a><br> - Gomes, L. (2020). μGIM - Microgrid intelligen management system based on a multi-agent approach and the active participation of end-users [Universidad de Salamanca]. <a href="http://doi.org/10.14201/gredos.144238">https://doi.org/10.14201/gredos.144238</a><br> - Gomes, L., Spínola, J., Vale, Z., & Corchado, J. M. (2019). Agent-based architecture for demand side management using real-time resources’ priorities and a deterministic optimization algorithm. Journal of Cleaner Production, 241, 118154. <a href="http://doi.org/10.1016/j.jclepro.2019.118154">https://doi.org/10.1016/j.jclepro.2019.118154</a></p> <p> </p> <p><em>(if you used this dataset in your publications, please send us your information so we can add your publication to the list above)</em></p> <p> </p> <p>We would be grateful if you could acknowledge the use of this dataset in your publications. Please use the Zenodo publication to cite this work.</p>
Proteome annotation of Phytophthora oleae, isolate VK10A, causative agent of rot of olive drupes.
<p>The proteome of Phytophthora oleae, isolate VK10A, causative agent of rot of olive drupes was predicted by using the genomic sequence (AUGUSTUS/GeneMark-ES) as described before (<a href="https://doi.org/10.5281/zenodo.11092245">https://doi.org/10.5281/zenodo.11092245</a>) and <em>de novo</em> mRNA assembly carried out by Trinity and GeneMark. Here, we present the proteome annotation of both genomic CDS and ORF, these latter derived from sense and antisense orientation of <em>de novo</em> mRNA. </p>
Dataset of docked structures for Topoisomerases-Histone Deacetylase-Dual Targeted Quinoline-Bridged Hydroxamates as Anticancer Agents
<p>The dataset contains docking poses of inhibitors 5C and 5G in the binding site of human TopoIIα, docking poses of inhibitors 5C and 5G in the binding site of human TopoI-DNA complex, docking poses of inhibitors 5C and 5G in the binding sites of HDAC1, HDAC6 and HDAC8 and protein-protein docking poses of hTopoIIα and HDAC1. All files are provided in pdb format. </p>
Figures 11-12 from: (2014) A new species of Gadirtha Walker (Nolidae, Eligminae): a proposed biological control agent of Chinese tallow (Triadica sebifera (L.) Small) (Euphorbiaceae) in the United States. ZooKeys 382: 13-25. https://doi.org/10.3897/zookeys.382.6600
Figures 11-12 - Larva of Gadirtha fusca sp. n. (preserved in alcohol). 11 dorsal 12 ventral.
Figures 7-8 from: (2014) A new species of Gadirtha Walker (Nolidae, Eligminae): a proposed biological control agent of Chinese tallow (Triadica sebifera (L.) Small) (Euphorbiaceae) in the United States. ZooKeys 382: 13-25. https://doi.org/10.3897/zookeys.382.6600
Figures 7-8 - Aedeagi of Gadirtha species. 7 Gadirtha fusca sp. n. 8 Gadirtha impingens Walker.
Figures 13-14 from: (2014) A new species of Gadirtha Walker (Nolidae, Eligminae): a proposed biological control agent of Chinese tallow (Triadica sebifera (L.) Small) (Euphorbiaceae) in the United States. ZooKeys 382: 13-25. https://doi.org/10.3897/zookeys.382.6600
Figures 13-14 - Larva of Gadirtha fusca sp. n. 13 on Chinese tallow 14 on Chinese tallow.
Simulation results of an agent-based model of civil violence with the effect of introducing a small world network
<p>The data set contains the simulation results of an agent-based model of civil violence with the effect of introducing a small world network. Some details on the agent-based model (without small world network) can be found in [Maria Fonoberova, Vladimir A. Fonoberov, Igor Mezic, Jadranka Mezic and P. Jeffrey Brantingham, Nonlinear Dynamics of Crime and Violence in Urban Settings, Journal of Artificial Societies and Social Simulation, 15(1), 2, http://jasss.soc.surrey.ac.uk/15/1/2.html, DOI: 10.18564/jasss.1921].</p> <p>Files in folder "Appropriate_Rate_of_Violence" are related to the case with the appropriate rate of violence.</p> <p>Subfolder NoSWN_CitVis_14 is for the case with no small world network and the citizen vision of 14.</p> <p>Subfolder SWN_CitVis_13.16 is for the case with small world network and the citizen vision of 13.16.</p> <p>Subfolder SWN_CitVis_14 is for the case with small world network and the citizen vision of 14.</p> <p>Each file with name starting with Act has one row for each time step of the simulation and has columns that are: number of active citizens, number of intimidated citizens, number of LEOs, number of non-intimidated citizens. These files are provided for lattice sizes from 100x100 to 300x300 and for different random seeds.</p> <p>Files in folder "High_Rate_of_Violence" are related to the case with the high rate of violence.</p> <p>Subfolder Beta0.2 is for the case with small world network and \beta=0.2.</p> <p>Subfolder Beta0.8 is for the case with small world network and \beta=0.8.</p> <p>Subfolder NoSWN is for the case with no small world network.</p> <p>Each file with name starting with Actives has one row for each time step of the simulation and has columns that are: number of active citizens, number of intimidated citizens, number of LEOs, number of non-intimidated citizens. These files are provided for lattice sizes from 100x100 to 300x300 and for different random seeds.</p>
Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD- 1 agents
<p><strong>ABSTRACT</strong></p> <p><strong>Background</strong></p> <p>CD73 is an ectonucleotidase producing the immunosuppressor mediator adenosine. Elevated levels of circulating CD73 in patients with cancer have been associated with disease progression and poor response to immunotherapy. Immunosuppressive pathways associated with exosomes can affect T-cell function and the therapeutic efficacy of anti-programmed cell-death<br> protein 1 (anti-PD-1) therapy. Here, we conducted a retrospective pilot study to evaluate levels of exosomal CD73 before and<br> early during treatment with anti-PD-1 agents in patients with melanoma and its potential contribution to affect T-cell functions and to influence the clinical outcomes of anti-PD-1 monotherapy.</p> <p><strong>Methods</strong></p> <p>Exosomes were isolated by mini size exclusion chromatography from serum of patients with melanoma (n=41) receiving nivolumab or pembrolizumab monotherapy. Expression of CD73 and programmed death-ligand 1 (PD-L1) were evaluated on exosomes enriched<br> for CD63 by on-bead flow cytometry. The CD73 AMPase activity was evaluated by mass spectrometry, also in the presence of selective inhibitors of CD73. Interferon (IFN)-γ production and granzyme B expression were measured in CD3/28 activated T cells incubated with exosomes in presence of the CD73 substrate AMP. Levels of CD73 and PD-L1 on exosomes were correlated with therapy response. Exosomes isolated from healthy subjects were used as control.</p> <p><strong>Results</strong></p> <p>Isolated exosomes carried CD73 on their surface, which is enzymatically active in producing adenosine. Incubation of exosomes with CD3/28 activated T cells in the presence of AMP resulted in a significant reduction of IFN-γ release, which was reversed by the<br> CD73 inhibitor APCP or by the selective A2A adenosine receptor antagonist ZM241385. Expression levels of exosomal CD73 from serum of patients with melanoma were not significantly different from those in healthy subjects. Early on-treatment, expression levels of both CD73 and PD-L1 on exosomes isolated from patients receiving pembrolizumab or nivolumab monotherapy were<br> significantly increased compared with baseline. Early during therapy exosomal PD-L1 increased in responders, while exosomal CD73 resulted significantly increased in non-responders.</p> <p><strong>Conclusions </strong></p> <p>CD73 expressed on exosomes from serum of patients with melanoma produces adenosine and contributes to suppress T-cell functions. Early on-treatment, elevated expression levels of exosomal CD73 might affect the response to anti-PD-1 agents in patients with melanoma who failed to respond to therapy.</p> <p> </p> <p><strong>Funding </strong></p> <p>This work was supported by FARB 2020 University of Salerno (SM), P.O.R. Campania FESR 2007–2013 - O.O. 2.1 - OCKEY (SM), POR Campania, FESR 2014/2020 (Asse 1—Obiettivo specifico 1.2—Azione 1.2) Project: Campania OncoTerapie CUP: B61G18000470007 and Italian Ministry of Health (IT-MOH) through 'Ricerca Corrente' M2/M (PAA).</p>
Agent-Based Social Skills Training Systems: A Comprehensive Analysis of Commercial Solutions
<p>Agent-based social skills training systems have been gaining attention for their potential to improve social skills development in various contexts. Through a rapid review methodology, data was collected from diverse sources, including company websites and research papers. This study then uses the collected data to categorize 8 commercial systems based on their agent model and feedback approaches, into two categorization tables. The findings reveal notable trends in the use of choice-based input, scenario-defined decision-making, and post-interaction feedback. Additionally, the paper discusses the limitations of these findings, highlights characteristics of commercial systems and compares them to research systems, as well as suggesting areas for future research. This study contributes to the understanding and advancement of agent-based social skills training systems, offering guidance to researchers in this field.</p>
Patient Centered Multi-Agent Decision Support System (PCM-DSS) for Healthcare Providers
ClinicalTrials.gov study NCT07063420. IPD Sharing: YES. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.