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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Disrupted processing of long pre-mRNAs and widespread RNA missplicing are components of neuronal vulnerability from loss of nuclear TDP-43 (RNA-seq)
GEO Series GSE27218. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Protracted NP95 binding to hemimethylated DNA disrupts SETDB1-mediated proviral silencing
GEO Series GSE77781. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes
GEO Series GSE48007. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
Increased global DNA methylation disrupts skeletal muscle homeostasis, promotes age-related decline in muscle function, and reduces muscle plasticity
GEO Series GSE244432. Mus musculus. 12 samples. Type: Methylation profiling by high throughput sequencing.
Disruption of jejunal and ileum homeostasis by malnutrition in systemic jejunal and ileum microbiota-host interactions in a pregnant sheep model
GEO Series GSE284288. Ovis aries. 20 samples. Type: Expression profiling by high throughput sequencing.
Targeted disruption of the BCL9/beta-catenin complex in cancer
GEO Series GSE33143. Homo sapiens. 6 samples. Type: Expression profiling by array.
EC-8042 disrupts both the primary SP/KLF transcription regulatory network and the secondary network induced by HDACi treatment. [H3K27me3 ChIP-seq]
GEO Series GSE268111. Homo sapiens. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Indel rate analysis:Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
GEO Series GSE146998. Mus musculus. 4 samples. Type: Other.
KDM4 inhibition disrupts the core regulatory transcriptional circuitry in MYCN-driven neuroblastoma [ATAC-seq]
GEO Series GSE164450. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Expression data from rat regenerating livers after autonomic nervous system is disrupted
GEO Series GSE26138. Rattus norvegicus. 18 samples. Type: Expression profiling by array.
Targeted p63 isoform modulation corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis [human RNA-seq]
GEO Series GSE297767. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [INTS-11 ChIP-Seq]
GEO Series GSE254787. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of the Circadian Clock within the Cardiomyocyte
GEO Series GSE10045. Mus musculus. 130 samples. Type: Expression profiling by array.
Angiotensin II disrupts the cytoskeletal architecture of human urine-derived podocytes and results in activation of the renin-angiotensin system
GEO Series GSE171240. Homo sapiens. 16 samples. Type: Expression profiling by array.
ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells [scRNA-seq]
GEO Series GSE280214. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic Repogramming by an Environmental Carcinogen Through Chromatin Domain Disruption [RNA-Seq]
GEO Series GSE56052. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
TET2 and TET3 loss disrupts small intestine differentiation and homeostasis [scRNA-seq]
GEO Series GSE200229. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Mutant p53 Disrupts Mammary Acinar Morphogenesis via the Mevalonate Pathway
GEO Series GSE31812. Homo sapiens. 6 samples. Type: Expression profiling by array.
Disruption of Immune Responses By Type I Diabetes Exacerbates SARS-CoV-2 Mediated Lung Injury [bulk RNA-seq]
GEO Series GSE276775. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Integrated data analysis reveals distinct drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas
GEO Series GSE86961. Homo sapiens. 82 samples. Type: Methylation profiling by genome tiling array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.