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1,723
datasets available to search
ShareScore release 0.9.0
Dataset results
1,723 results for “Reactivation”
Next Generation Sequencing to determine HHV-6B Transcriptome in HCT patients with a recent viral reactivation
GEO Series GSE115533. Homo sapiens; Human betaherpesvirus 6B. 5 samples. Type: Expression profiling by high throughput sequencing.
NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering chemotherapeutic drugs and reactivating NK cell functions
GEO Series GSE217191. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Stress triggers expression of bovine herpesvirus 1 infected cell protein 4 (bICP4) RNA during early stages of reactivation from latency in pharyngeal tonsil
GEO Series GSE216685. Bos taurus. 12 samples. Type: Expression profiling by high throughput sequencing.
Integrated single-cell multiomic analysis of HIV latency reversal reveals novel regulators of viral reactivation
GEO Series GSE242997. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Differential transcriptome analysis of naïve T cell activtion, TH1 cell differentiation and TH1 cell reactivation
GEO Series GSE222902. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Lysophosphatidylcholine acyltransferase 1 controls the mitochondrial reactive oxygen species generation and survival of the retinal photoreceptor cells
GEO Series GSE184818. Mus musculus. 16 samples. Type: Expression profiling by array.
Pharmacological Targeting of REV-ERBa/bPromotes HIV-1 Reactivation in CD4+T-Cells while Limiting Cell-to-Cell Dissemination
GEO Series GSE253420. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Chemotherapy-induced reactive myelopoiesis leads to expansion of immunosuppressive neutrophil-like monocytes in mice and humans [scRNA-Seq]
GEO Series GSE314231. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (DNA methylation data set)
GEO Series GSE122808. Homo sapiens. 14 samples. Type: Methylation profiling by genome tiling array.
Exogenous melatonin promotes rice seed germination under salinity through regulating reactive oxygen species and phytohormones
GEO Series GSE143922. Oryza sativa. 9 samples. Type: Expression profiling by high throughput sequencing.
Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model
GEO Series GSE95297. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of apoplastic reactive oxygen species (ROS) signaling and dissection of the roles of WRKY25, WRKY33 and WRKY75 in the transcriptional reprogramming triggered by apoplastic ROS
GEO Series GSE79855. Arabidopsis thaliana. 20 samples. Type: Expression profiling by high throughput sequencing.
Cadmium interference with iron sensing reveals transcriptional programs sensitive and insensitive to reactive oxygen species
GEO Series GSE128156. Arabidopsis thaliana. 36 samples. Type: Expression profiling by high throughput sequencing.
Bulk-RNA and single-cell RNA sequencing of Nasopharyngeal Carcinoma Cell lines infected with Epstein-Barr virus (EBV) subjected to air-liquid interface (ALI)-induced reactivation
GEO Series GSE231689. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy [Human bulk RNA-seq]
GEO Series GSE190451. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
FOXM1-mediated regulation of reactive oxygen species and radioresistance in oral squamous cell carcinoma cells
GEO Series GSE210922. Homo sapiens. 10 samples. Type: Expression profiling by array.
Enhancer reactivation mediates adaptive resistance to FGFR inhibitors in triple-negative breast cancer [RNA_seq]
GEO Series GSE168023. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT"
<p>This record contains data set related to the article "Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT"</p> <p>Haploidentical hematopoietic stem cell transplantation (h-HSCT) represents an efficient curative approach for patients affected by hematologic malignancies in which the reduced intensity conditioning induces a state of immunologic tolerance between donor and recipient. However, opportunistic viral infections greatly affect h-HSCT clinical outcomes. NK cells are the first lymphocytes that recover after transplant and provide a prompt defense against human cytomegalovirus (HCMV) infection/reactivation. By undertaking a longitudinal single-cell computational profiling of multiparametric flow cytometry, we show that HCMV accelerates NK cell immune reconstitution together with the expansion of CD158b1b2jpos/NKG2Aneg/NKG2Cpos/NKp30lo NK cells. The frequency of this subset correlates with HCMV viremia, further increases in recipients experiencing multiple episodes of viral reactivations, and persists for months after the infection. The transcriptional profile of FACS-sorted CD158b1b2jpos NK cells confirmed the ability of HCMV to deregulate NKG2C, NKG2A, and NKp30 gene expression, thus inducing the expansion of NK cells with adaptive traits. These NK cells are characterized by the downmodulation of several gene pathways associated with cell migration, the cell cycle, and effector-functions, as well as by a state of metabolic/cellular exhaustion. This profile reflects the functional impairments of adaptive NK cells to produce IFN-γ, a phenomenon also due to the viral-induced expression of lymphocyte-activation gene 3 (LAG-3) and programmed cell death protein 1 (PD-1) checkpoint inhibitors.</p>
Longitudinal humoral analysis in RSV-infected infants points to pre-existing strain-specific G and evolving cross-reactive F antibodies against RSV
<p>dataset for "Longitudinal humoral analysis in RSV-infected infants points to pre-existing strain-specific G and evolving cross-reactive F antibodies against RSV"</p>
NMR based Synovial fluid metabolomics analysis of Reactive arthritis, Rheumatoid arthritis and Osteoarthritis
<p>Reactive arthritis (ReA) is an inflammatory arthritis that often develops 2–4 weeks after an extraarticular infection with Chlamydia, Salmonella, Shigella, Campylobacter, and Yersinia species. Synovial fluid (SF) represents the diseased process under pathological conditions and its distinctive metabolic profiles may provide the diagnostic capacity and understanding of the disease state of reactive arthritis (ReA). The aim of this study is to identify characteristic metabolic changes that could differentiate ReA from non-ReA groups. The metabolic profiles of SF collected from ReA (n=58), rheumatoid arthritis (RA, n=21) and osteoarthritis (OA, n=20) patients were measured using NMR spectroscopy and compared using orthogonal partial least-squares discriminant analysis (OPLS-DA). Further, the receiver-operating characteristic (ROC) curve analysis was performed to establish the diagnostic potential of discriminatory metabolites. Finally, the correlation analysis of 38 metabolites between paired SF and serum from ReA patients was done using Pearson rank coefficient (r). The metabolomics profiles in synovial fluid were distinct between ReA, RA, and OA. The OPLS-DA demonstrated a distinctive metabolite profile of synovial fluid of ReA patient compare to RA RA and OA. Fourteen metabolites were obtained by VIP values of greater than 1 for both groups (ReA vs OA and ReA vs RA) and 12 and 6 of them were selected as potential biomarkers by student t-test for ReA vs OA and ReA vs RA groups. We utilized receiver operating characteristic analysis to determine the diagnostic value of each metabolite and identified in ReA compare to RA and OA as potential biomarkers, with an area under the ROC curve >0.8. A panel of six metabolites (NAG, glutamate, glycerol, isoleucine, alanine and glucose from ReA vs OA group) and two metabolites (alanine and carnitine from ReA vs RA group) was identified as a specific biomarker of ReA. Finally, the pearson correlation coefficient (r) between serum and SF ranged from -0.17 to 0.87 for each of the 38 metabolites, and 71% of the relations were significantly positive. Our approach successfully identified SF biomarkers associated with ReA patients that could serve as an efficient tool for early diagnosis of ReA and the role of these biomarker in the pathogenesis of ReA should be explored in future studies. This is the first study that establishes the correlation between metabolic profiles in SF and serum obtained from ReA patients.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.