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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Insulin resistance disrupts midbrain metabolic and functional homeostasis and aggravates dopaminergic neuron loss in GBA-PD via FOXO1 overexpression.
GEO Series GSE237116. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs
GEO Series GSE116387. Homo sapiens. 24 samples. Type: Expression profiling by array; Other.
ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells [bulk RNA-seq]
GEO Series GSE296358. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
HDAC6 Inhibition Disrupts HDAC6-P300 Interaction Reshaping the Cancer Chromatin Landscape (ChIP-Seq)
GEO Series GSE273645. Mus musculus; Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Pathogenic Mutation that Dislocates GATA2 Zinc Fingers Establishes a Hematopoiesis-Disrupting Signaling Network
GEO Series GSE201968. Mus musculus. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Prenatal Bisphenol A Exposure in Mice Induces Multi-tissue Multi-omics Disruptions Linking to Cardiometabolic Disorders
GEO Series GSE121606. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae
GEO Series GSE87060. Saccharomyces cerevisiae. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Binge Alcohol Disrupts Skeletal Muscle Core Molecular Clock Independent of Glucocorticoids
GEO Series GSE183665. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Silencing of BCL11A by Disrupting Enhancer-Dependent Chromatin Insulation
GEO Series GSE292698. Homo sapiens. 95 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Genome-wide chromatin accessibility profiles of TET2-disrupted T cells from a chronic lymphocytic leukemia (CLL) patient.
GEO Series GSE112494. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock
GEO Series GSE134974. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA [PROseq]
GEO Series GSE267042. Homo sapiens. 6 samples. Type: Other.
Characterization of estrogen and the endocrine-disrupting chemical-induced mouse mammary gland reorganization
GEO Series GSE228190. Homo sapiens; Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Lipid metabolism dysregulation in solar lentigo: a multi-system-level analysis reveals membrane instability and energy homeostasis disruption
GEO Series GSE318414. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
The U1 antisense morpholino oligonucleotide (AMO) disrupts U1 snRNP structure to promote intronic PCPA modification of pre-mRNAs
GEO Series GSE192943. Homo sapiens. 78 samples. Type: Other; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA [48h_INTS8_RNAseq]
GEO Series GSE283862. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Insulin resistance disrupts midbrain metabolic and functional homeostasis and aggravates dopaminergic neuron loss in GBA-PD via FOXO1 overexpression [WTs]
GEO Series GSE237114. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
A MYT1L Syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
GEO Series GSE173943. Mus musculus. 57 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Transcriptional heterogeneity overcomes super-enhancer disrupting drug combinations in multiple myeloma [ChIP-seq]
GEO Series GSE244002. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Stimulative effect of low-dose neonicotinoid pesticide, clothianidin on human neuroblastoma SH-SY5Y cells by disrupting intracellular signaling
GEO Series GSE126103. Homo sapiens. 4 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.