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1,642 results for “vein”
Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors
<p>The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: <a href="https://www.ncbi.nlm/">https://www.ncbi.nlm</a>. nih.gov/, GSE192712</p> <p>Intimal hyperplasia is the leading cause of graft failure in aortocoronary bypass grafts<br> performed using human saphenous vein (SV). The long-termconsequences of the altered<br> pulsatile stress on the cells that populate the vein wall remains elusive, particularly<br> the effects on saphenous vein progenitors (SVPs), cells resident in the vein adventitia<br> with a relatively wide differentiation capacity. In the present study, we performed global<br> transcriptomic profiling of SVPs undergoing uniaxial cyclic strain in vitro. This type of<br> mechanical stimulation is indeed involved in the pathology of the SV. Results showed<br> a consistent stretch-dependent gene regulation in cyclically strained SVPs vs. controls,<br> especially at 72 h. We also observed a robust mechanically related overexpression of<br> Adhesion Molecule with Ig Like Domain 2 (AMIGO2), a cell surface type I transmembrane<br> protein involved in cell adhesion. The overexpression of AMIGO2 in stretched SVPs<br> was associated with the activation of the transforming growth factor b pathway and<br> modulation of intercellular signaling, cell-cell, and cell-matrix interactions. Moreover,<br> the increased number of cells expressing AMIGO2 detected in porcine SV adventitia<br> using an in vivo arterialization model confirms the upregulation of AMIGO2 protein<br> by the arterial-like environment. These results show that mechanical stress promotes<br> SVPs’molecular phenotypic switching and increases their responsiveness to extracellular<br> environment alterations, thus prompting the targeting of new molecular effectors to<br> improve the outcome of bypass graft procedure.</p>
An image dataset for estimation of nuclei density of lobules related to Cell atlas of the regenerating human liver after portal vein embolization
<p>Dataset of Tissue samples for cell atlas</p> <p>datafilename coding:<br>first Character: sex of patient ( B- men, K- women) <br>second char: condition (0- conroll, 1- embolized, 2- regenerated)<br>next chars to Letter: Date of Dataset<br>Letter char with number: Lobule of Marker Charge( G- GLUL)</p> <p>Tiff: fiji proceed images<br>zip: coordinates for fiji<br>csv: cleaned and readable format of coordinates for python<br>PNG: Hoechst marked Nuclei of GLUL marker</p> <p> </p> <p> </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.