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TCR convergence is a indicator of antigen-specific T cell response in immunotherapies
<p>This compressed file contains all the convergent TCR sequence information involved in this study. </p>
Lipidomic profiling indicate protection of hypoxic-ischemic brain injury on neonatal rats ingesting Acer truncatum Bunge oil
<p>Hypoxic ischemic encephalopathy (HIE) has a serious effect on newborn growth and development, and there are currently no effective interventions. In this study, we discovered administering <em>Acer truncatum Bunge seed </em>oil (ASO) for 30 days reduces the damage caused by HIE and improves the learning and memory ability. Using lipidomics approaches to compare metabolite changes in HIE and sham rats, we discovered that glycerophospholipids, plasmalogen, unsaturated fatty acids decreased and lysophospholipids increased in HIE rats' brain. After 30 days of ASO treatment, glycerophospholipids, plasmalogen, and unsaturated fatty acids increased in serum and brain, while lysophospholipids and oxidized glycerophospholipids decreased. Based on cluster, correlation and attribution analysis, we find changes of glycerophospholipids, plasmalogen, w3/6/9 fatty acid, oxidized GP and lysophospholipids contributes to improvement of cognitive ability, indicated by eliminating the oxidative injury by HIE. Our findings suggest that ASO may be a potential special medical food for ischemic hypoxic newborns.</p>
FIGURE 31 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURE 31. The ML tree showing unique base changes per phylogroups of Bolua, obtained by maximum parsimony analysis (the base position indicates by the position number in the concatenated matrix)
FIGURES 28–30 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURES 28–30. Song in Bolua (28—B. balikesirensis from Balıkesir; 29—and 30—B. bursaensis from Bursa and Kütahya, respectively; A, B and C show song at three different time scale)
FIGURES 18–26. 18–20 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURES 18–26. 18–20. Female head+pronotum+tegmina in Bolua (18—B. turkiyae, 19—B. balıkesirensis, 20—B. bursaensis; D—dorsal view, L—lateral view). 21–23. Female subgenital plate in Bolua (21—B. turkiyae, 22—B. balıkesirensis, 23—B. bursaensis; V—ventral view, L-lateral view). 24–26. Ovipositor in Bolua (24—B. turkiyae, 25—B. balıkesirensis, 26— B. bursaensis)
FIGURE 2 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURE 2. Phylogenetic tree, chronogram and taxonomic pattern obtained from the matrix constituted by concatenation of COI+NAD2+VAL+ITS sequences. The bootstrap (ML)/ posterior probability (BI) supports to the node are given above the node and the time to the most recent common ancestor (TMRCA) and the 95% HPD as million years below the node. The results from the species delimitation test are indicated by a bar line.
FIGURE 27 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURE 27. The PCA plots and trait contribution prepared from the metric data sets of male and female individuals belonging to Bolua
FIGURE 1 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURE 1. Distribution of Bolua [for detail of the localities see material examined per species; Bolu(1), Kastamonu (2,3,4, 6), Karabük (5), Çankırı (7), Balıkesir (8), Bursa (9, 10), Kütahya (11) and Kocaeli (12, 13)]
FIGURES 3–17. 3–5 in Anatolian endemic genus Bolua (Orthoptera: Tettigoniidae: Tettigoniinae): genetic and phenotypic data indicate inconsistent diversity and evolutionary patterns
FIGURES 3–17. 3–5. Male head+pronotum+tegmina in Bolua (3—B. turkiyae, 4—B. balıkesirensis, 5—B. bursaensis; D— dorsal view, L—lateral view). 6–8. Male anal tergite in Bolua (6—B. turkiyae, 7—B. balıkesirensis, 8—B. bursaensis). 9–11. Male cercus in Bolua (9—B. turkiyae, 10—B. balıkesirensis, 11—B. bursaensis). 12–14. Male subgenital plate in Bolua (12—B. turkiyae, 13—B. balıkesirensis, 14—B. bursaensis). 15–17. Titillators in Bolua (15—B. turkiyae, 16—B. balıkesirensis, 17—B. bursaensis)
Supplemental information for "Single-Molecule Dynamics of Surface Lipoproteins in Bacteroides Indicate Similarities and Cooperativity"
<p>Supplemental Movies 1 - 3</p> <p><strong>SI Movie S1 - Representative movie of SusG-HT dynamics in <em>Bt</em> cells grown in amylopectin.</strong> The <em>Bt</em> cell outlines (white) are determined from the corresponding phase-contrast image. The single-molecule localization fits (circles) and corresponding trajectories (lines) are overlaid with the same colors as in Figure 1c. Below the scale bar is the date of the experiment, the movie number, the number of the photo-activation pulse that the sequence follows (in parentheses), and the frame number. These indicators are displayed in green during the imaging frames and in red during the photo-activation pulse. Scale bar: 1 µm; imaging rate: 20 ms/frame.</p> <p><strong>SI Movie S2 - Representative movie of SusG-HT dynamics in <em>Bt</em> cells grown in maltose.</strong> The <em>Bt</em> cell outlines (white) are determined from the corresponding phase-contrast image. The single-molecule localization fits (circles) and corresponding trajectories (lines) are overlaid with the same colors as in Figure 1c. Below the scale bar is the date of the experiment, the movie number, the number of the photo-activation pulse that the sequence follows (in parentheses), and the frame number. These indicators are displayed in green during the imaging frames and in red during the photo-activation pulse. Scale bar: 1 µm; imaging rate: 20 ms/frame.</p> <p><strong>SI Movie S3 - Representative movie of SusG-HT dynamics in <em>Bt</em> cells grown in glucose.</strong> The <em>Bt</em> cell outlines (white) are determined from the corresponding phase-contrast image. The single-molecule localization fits (circles) and corresponding trajectories (lines) are overlaid with the same colors as in Figure 1c. Below the scale bar is the date of the experiment, the movie number, the number of the photo-activation pulse that the sequence follows (in parentheses), and the frame number. These indicators are displayed in green during the imaging frames and in red during the photo-activation pulse. Scale bar: 1 µm; imaging rate: 20 ms/frame.</p>
Supplementary material 2 from: Decker P (2016) Phylogenetic analysis of the Australian trans-Bass Strait millipede genus Pogonosternum (Carl, 1912) (Diplopoda, Polydesmida, Paradoxosomatidae) indicates multiple glacial refugia in southeastern Australia. ZooKeys 578: 15-31. https://doi.org/10.3897/zookeys.578.8052
Alignment of combined dataset : Explanation note: Alignment of the combined COI mtDNA and 16S rRNA dataset
Supplementary material 3 from: Decker P (2016) Phylogenetic analysis of the Australian trans-Bass Strait millipede genus Pogonosternum (Carl, 1912) (Diplopoda, Polydesmida, Paradoxosomatidae) indicates multiple glacial refugia in southeastern Australia. ZooKeys 578: 15-31. https://doi.org/10.3897/zookeys.578.8052
P-distances of combined COI and 16S dataset : Explanation note: Mean uncorrected pairwise distances between terminals (transformed into percentages) of the combined COI mtDNA and 16S rRNA dataset.
Supplementary material 1 from: Decker P (2016) Phylogenetic analysis of the Australian trans-Bass Strait millipede genus Pogonosternum (Carl, 1912) (Diplopoda, Polydesmida, Paradoxosomatidae) indicates multiple glacial refugia in southeastern Australia. ZooKeys 578: 15-31. https://doi.org/10.3897/zookeys.578.8052
Full data of sequenced specimens : Explanation note: Full details of sequenced specimens, including locality, date, collector, collection number and coordinates.
Supplementary material 3 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Documentation on phylogeny.: Explanation note: This is a list of references including the most relevant sources of information used to build the hypothesis on phylogenetic relationships which were not quoted in the main text.
Supplementary material 2 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Frequency distribution graph.: Explanation note: Frequency distribution of the dry body weight data (mg) across the species studied.
Supplementary material 5 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Mean by superfamily.: Explanation note: Mean dry body weight and wing length by superfamily, and sample sizes.
Supplementary material 4 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Tree topology.: Explanation note: Graphic display (dendrogram) to show the hypothesis on phylogenetic relations adopted in this work, after the sources quoted in the main texta and in the file: Supplementary material 3.
Supplementary material 6 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Alternative models.: Explanation note: Alternative or suboptimal regression models derived from the species means or from the independent contrasts.
Supplementary material 1 from: García-Barros E (2015) Multivariate indices as estimates of dry body weight for comparative study of body size in Lepidoptera. Nota Lepidopterologica 38(1): 59-74. https://doi.org/10.3897/nl.38.8957
Nexus format text.: Explanation note: Tree topology for the phylogenetic hypothesis adopted, to be used as input in applications reading nexus (requires some slight previous edition).
Text - fig. 4 — Femur of Albertosaurus cf. A. lancensis (LACM 23845) in anterior aspect. Diagonal lines indicate broken surfaces. Bar represents 10 cm. in An albertosaur from the Hell Creek formation of Montana
Text - fig. 4 — Femur of Albertosaurus cf. A. lancensis (LACM 23845) in anterior aspect. Diagonal lines indicate broken surfaces. Bar represents 10 cm.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.