Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
Alteration of DNMT1/DNMT3A by eribulin elicits global DNA methylation changes with potential therapeutic implications for triple-negative breast cancer
GEO Series GSE234881. Homo sapiens. 11 samples. Type: Methylation profiling by genome tiling array.
The therapeutic potential and significance of the PELP1 signaling pathway in hepatocellular carcinoma
GEO Series GSE254860. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas [ChIP-Seq]
GEO Series GSE129135. Homo sapiens. 80 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumor
GEO Series GSE262030. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing.
Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target
GEO Series GSE274781. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma [bulk RNA-seq]
GEO Series GSE223061. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing.
Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer [RNA-seq_RBKO vs WT]
GEO Series GSE236498. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Mouse Models of Pediatric Acute Megakaryoblastic Leukemia Reveal Novel Therapeutic Vulnerabilities [DSP798]
GEO Series GSE208157. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Identification of p38 beta as a therapeutic target for the treatment of Sézary Syndrome
GEO Series GSE59179. Homo sapiens. 20 samples. Type: Expression profiling by array.
The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age [RNA-seq]
GEO Series GSE280699. Mus musculus. 78 samples. Type: Expression profiling by high throughput sequencing.
UTX Loss Alters Therapeutic Responses in KMT2A-rearranged Acute Myeloid Leukemia [RNA-seq]
GEO Series GSE214158. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Epinecidin-1 has immunomodulatory effects, facilitating its therapeutic use in a mouse model of Pseudomonas aeruginosa sepsis
GEO Series GSE57976. Mus musculus. 4 samples. Type: Expression profiling by array.
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma
GEO Series GSE276715. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Tamoxifen treatment as a therapeutic approach in a murine model of X-linked myotubular myopathy (Mtm1-/y)
GEO Series GSE160083. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Pleiotropic impact of DNA-PK in cancer and implications to therapeutic strategies
GEO Series GSE116765. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
PROTACs therapeutically target the polyglutamine androgen receptor inspinal and bulbar muscular atrophy models
GEO Series GSE297069. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer and nominates c-Met and TRIM24 as therapeutic targets
GEO Series GSE165407. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.
P300-mediated adaptive conversion of glioma stem cells to vascular-like cells in response to therapeutic stress promotes tumor recurrence [scRNAseq in vitro]
GEO Series GSE207725. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Loss of NF2 drives malignant transformation of human pancreatic acinar cells and enhances cell fitness under nutrient deprivation and therapeutical stress [CRISPR_screen]
GEO Series GSE292511. Homo sapiens. 16 samples. Type: Other.
TRIM24 as therapeutic target in endocrine treatment resistant breast cancer
GEO Series GSE246796. Homo sapiens. 67 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.