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18,658 results for “impacts”
Supplementary Materials include results of simulation experiments to investigate the impact of phylogenetic regression with model violations.
<p>Modern comparative biology owes much to phylogenetic regression. At its conception, this technique sparked a revolution that armed biologists with phylogenetic comparative methods (PCMs) for disentangling evolutionary correlations from those arising from hierarchical phylogenetic relationships. Over the past few decades, the phylogenetic regression framework has become a paradigm of modern comparative biology that has been widely embraced as a remedy for shared ancestry. However, recent evidence has sown doubt over the efficacy of phylogenetic regression, and PCMs more generally, with the suggestion that many of these methods fail to provide an adequate defense against unreplicated evolution—the primary justification for using them in the first place. Importantly, some of the most compelling examples of biological innovation in nature result from abrupt lineage-specific evolutionary shifts, which current regression models are largely ill-equipped to deal with. Here we explore a solution to this problem by applying robust linear regression to comparative trait data. We formally introduce robust phylogenetic regression to the PCM toolkit with linear estimators that are less sensitive to model violations than the standard least-squares estimator, while still retaining high power to detect true trait associations. Our analyses also highlight an ingenuity of the original algorithm for phylogenetic regression based on independent contrasts, whereby robust estimators are particularly effective. Collectively, we find that robust estimators hold promise for improving tests of trait associations and offer a path forward in scenarios where classical approaches may fail. Our study joins recent arguments for increased vigilance against unreplicated evolution and a better understanding of evolutionary model performance in challenging–yet biologically important–settings.</p>
Data for "Impact of Surface Adsorbates and Dimensionality on Templating of Halide Perovskites"
<p>This record contains databases with data from density functional theory calculations used for training of a neuroevolution potential (NEP) for 2D halide perovskites. </p>
Impact of persistently high sea surface temperatures on the rhizobiomes of Zostera marina in a Baltic Sea benthocosms
Open the record for dataset details and reuse information.
Data from: Mitonuclear interactions impact aerobic metabolism in hybrids and may explain mitonuclear discordance in young, naturally hybridizing bird lineages
<p>Understanding genetic incompatibilities and genetic introgression between incipient species are major goals in evolutionary biology. Mitochondrial genes evolve rapidly and exist in dense gene networks with coevolved nuclear genes, suggesting that mitochondrial respiration may be particularly susceptible to disruption in hybrid organisms. Mitonuclear interactions have been demonstrated to contribute to hybrid dysfunction between deeply divergent taxa crossed in the laboratory, but there are few empirical examples of mitonuclear interactions between younger lineages that naturally hybridise. Here we use controlled hybrid crosses and high resolution respirometry to provide the first experimental evidence in a bird that inter-lineage mitonuclear interactions impact mitochondrial aerobic metabolism. Specifically, respiration capacity of the two mitodiscordant backcrosses (with mismatched mito-nuclear combinations) differ from one another, although they do not differ significantly from the parental groups or mitoconcordant backcrosses as we would expect of mitonuclear disruptions. In the wild hybrid zone between these subspecies the mitochondrial cline centre is shifted west of the nuclear cline centre, which is consistent with the direction of our experimental results. Our results therefore demonstrate asymmetric mitonuclear interactions that impact the capacity of cellular mitochondrial respiration and may help to explain the geographic discordance between mitochondrial and nuclear genomes observed in the wild.</p>
Modeling the impacts of Antarctic Sea Ice Decline: Responses of Atmospheric Dynamics
Open the record for dataset details and reuse information.
Results from, "Causal health impacts of power plant emission controls under modeled and uncertain physical process interference."
<p>This repository contains results from the paper, "<a href="https://arxiv.org/abs/2306.05665">Causal health impacts of power plant emission controls under modeled and uncertain physical process interference</a>," by Wikle and Zigler (2024), to appear in <em>Annals of Applied Statistics</em>. The storage of these results helps facilitate access to and replication of the analysis in the paper. The results include output from the:</p> <ol> <li>Sulfate analysis <ul> <li>tx-2016-100k-int-mx.RDS</li> </ul> </li> <li>Asthma analysis <ul> <li>asthma-pois-cut.RDS</li> <li>asthma-pois-plugin.RDS</li> <li>asthma-bart-cut.RDS</li> <li>asthma-bart-plugin.RDS</li> </ul> </li> <li>Medicare analysis <ul> <li>medicare-pois-cut.RDS</li> <li>medicare-pois-plugin.RDS</li> <li>medicare-bart-cut.RDS</li> <li>medicare-bart-plugin.RDS</li> </ul> </li> <li>Simulation study <ul> <li>simstudy-cm1-lm.RDS</li> <li>simstudy-cm1-bart.RDS</li> <li>simstudy-cm2-lm.RDS</li> <li>simstudy-cm2-bart.RDS</li> <li>simstudy-cm3-lm.RDS</li> <li>simstudy-cm3-bart.RDS</li> <li>simstudy-pm1-pois.RDS</li> <li>simstudy-pm1-bart.RDS</li> <li>simstudy-pm2-pois.RDS</li> <li>simstudy-pm2-bart.RDS</li> <li>simstudy-pm3-pois.RDS</li> <li>simstudy-pm3-bart.RDS</li> </ul> </li> <li>Log-linear BART sensitivity analysis <ul> <li>sensitivity-m100.RDS</li> <li>sensitivity-m200.RDS</li> <li>sensitivity-m300.RDS</li> <li>sensitivity-m400.RDS</li> <li>sensitivity-power05.RDS</li> <li>sensitivity-power1.RDS</li> <li>sensitivity-power15.RDS</li> <li>sensitivity-power2.RDS</li> <li>sensitivity-power25.RDS</li> <li>sensitivity-power3.RDS</li> <li>sensitivity-power4.RDS</li> <li>sensitivity-power5.RDS</li> </ul> </li> </ol> <p>A description of these results can be found at <a href="https://github.com/nbwikle/estimating-interference">https://github.com/nbwikle/estimating-interference</a>, along with the R code used to generate these (and other results, such as figures) found in the manuscript and supplementary material.</p>
Sedimentary DNA of a human‐impacted lake in Western Canada (Cultus Lake) reveals changes in micro‐eukaryotic diversity over the past ~200 years
<p>Although the use of genetic analyses of sedimentary DNA to track changes in biodiversity has increased over the last decade, questions remain as to how well DNA captures past ecological conditions. Even less is known about how extracellular and intracellular DNA are archived in lake sediments and whether the two fractions yield similar information. Here we characterized the changes of micro‐eukaryotic communities over the past ~200 years in Cultus Lake (British Columbia, Canada), for which a rich body of limnological data and a pre‐existing multi‐proxy paleolimnological study exist. We generated and analyzed 18S rRNA gene amplicons and found that extracellular and intracellular DNA provided different insights, with the preservation of extracellular DNA compromised in sediments older than ~30 years. Principal Coordinates and indicator species analyses based on intracellular DNA showed that changes in micro‐eukaryotic diversity occurred at similar time periods as those identified with the classical paleolimnological study. For instance, decreases of Opisthokonta amplicons occurred during years with elevated numbers of sockeye salmon spawners, which might be associated with an increase of herbivory by juvenile sockeye salmon. Furthermore, two diatom species identified morphologically exhibited similar temporal dynamics to two diatom taxa identified genetically, suggesting that sedimentary DNA can track past diatom species changes as well as micro‐eukaryotic community changes. Overall, our study provides insights into the use of extracellular and intracellular DNA in sedimentary records and showed that sedimentary DNA enriches our understanding of micro‐eukaryotic community changes over centennial time scales.</p>
Metadata of the Top 40 Journals in Distance Education: A Bibliometric Analysis of Impact 2018-2022
<p>This file contains metadata from the 40 most impactful journals in the field of distance education, selected through a rigorous bibliometric analysis using the SCImago Journal Rank (SJR) indicator provided by SCImago. Two main criteria guided the selection: the first targeted journals ranked in Q1 and Q2 in the specific category of "e-learning" within the social sciences and education area, highlighting publications that demonstrate high impact and relevance in the academic community according to the selected indicator. The second criterion was based on keyword searches in the journal titles, selecting those that include terms like e-learning, online, Distance Education, Technology Learning, Communications in Information, and Information Education and their variants (e.g., plural), also positioned in Q1 or Q2.</p> <p>The metadata, extracted from the Scopus database, covers publications from the period 2018 to 2022 and includes vital information such as document type, authors' names, article title, journal name, publication year, pages, volume, and issue number. Additionally, each article is identified by a Digital Object Identifier (DOI) and URLs for direct access to the full text online, along with abstracts and keywords. These elements together provide a comprehensive and accessible view of the articles, facilitating bibliometric analyses and related academic research.</p> <p>This compilation serves as an essential resource for researchers and educators interested in understanding the dynamics and development of the field of distance education, offering a solid foundation for future investigations and the formulation of evidence-based educational policies.</p>
Data from: Frequency-dependent tolerance to aircraft disturbance drastically alters predicted impact on shorebirds
<p>This data package includes data and R script belonging to the publication "Frequency-dependent tolerance to aircraft disturbance drastically alters predicted impact on shorebirds" by van der Kolk et al. (2024) in Ecology Letters.</p> <p>The script analysis_figures_vanderKolketal2024.R can be used to reproduce all analysis and figures in the manuscript. The Figures are stored in the Output folder.</p> <p>The data folder includes an excel file with metadata explaining all columns in the csv files.</p>
Code and data for "Impact of Auditory Deprivation on Tennis Performance and Perceived Exertion"
<p>Written in R + RMarkdown. Using `renv` to manage dependencies. Run `renv::restore()` after loading the project to<br>obtain required libraries.</p> <p>Main contents description:</p> <p>- `auditory_deprivation.Rmd` the main analysis file<br>- `data/data ENG.xlsx` the main dataset</p>
Data from: Fake news? The impact of information mismatch in mating behaviour
<p>Multiple cues are often used for mate choice in complex environments, potentially entailing mismatches between different sources of information. We address the consequences thereof for receivers using the spider mite <em>Tetranychus urticae</em>, in which virgin females are highly valuable mates compared to mated females, given first male sperm precedence. Accordingly, males prefer virgins and distinguish them using cues from the females and/or that are present on the substrate. Whereas the former are more reliable, the latter may allow for a faster or more long-distance response. However, there can be mismatched information between cues as females move and/or mate. Here, we tested the consequences thereof by exposing males to mated or virgin females on patches previously impregnated with cues deposited by females of either mating status. Male mating attempts were solely affected by substrate cues while female acceptance and the number of mating events were independently affected by both cues. Copulation duration, in contrast, depended mainly on the mating status of the female, with the number of copulations and the total time spent mating being intermediate in environments with mismatched information. Ultimately, male survival costs mirrored male investment in mating. These results suggest that, in environments with mismatched information, the substrate cues left by females are instrumental for males to find their mates, but they can also lead to males paying survival costs without the associated benefit of mating effectively, or suffering reduced costs at the expense of losing effective mating opportunities. The benefit of using multiple cues will then hinge upon the frequency of information mismatch, which itself should vary with the dynamics of populations.</p>
Impact of background input on memory consolidation in In-Vitro neural networks
<p>Memory consolidation is a complex process, that can be divided into two stages: first, memories are temporary stored in hippocampus and in the second stage, repeated replay slowly transfers memories to the neo-cortex for long-term consolidation. This 2<sup>nd</sup> stage occurs during slow wave sleep, a phase characterized in the cortex by low cholinergic tone and low afferent input. A recent in-vitro study showed that high cholinergic tone hampers memory consolidation, probably due to lowered network excitability (defined as the mean network response to one neuron spiking). Here we investigate whether low background input contributes to memory consolidation.</p> <p>We used cortical neuronal networks on multi electrode arrays to study memory. When input deprived, these networks develop an activity-connectivity balance. Focal stimuli initially disrupt the existing balance, inducing connectivity changes. When repeated, this effect fades and the response becomes part of spontaneous patterns (memory formation). Application of the same stimulus hours later does not affect connectivity indicating that memory was consolidated.</p> <p>We applied five periods (10 min each) of focal electrical stimulation at different electrodes (A B A), separated by 1 hour of spontaneous activity . Some cultures were transfected to express channelrhopsins (ChR2) enabling global optogenetic background stimulation. We used 12 control, 15 ChR2 cultures with no background input and 8 ChR2 cultures with superimposed random optogenetic stimulation during electrical stimulation periods (f<sub>mean</sub>=5 Hz) to mimic afferent input.</p> <p>Background stimulation acutely reduced network excitability during stimulation without persisting effects after cessation. ChR2 cultures showed significantly more dispersed spiking outside network bursts, and network excitability tended to be lower than in control cultures. Stimulation at electrodes A and B induced memory traces in control cultures. Return to electrode A did not further affect connectivity, showing that memory trace A had been consolidated. Background stimulation impeded the formation of memory traces following electrical stimulation at either electrode. ChR2 expression alone also obstructed memorization.</p> <p>These findings confirm the importance of low background afferent input for memory consolidation. The presence of background afferent inputs reduced network excitability, similar to high cholinergic tone. This leads to the conclusion that sufficient network excitability is crucial for memory consolidation, and high network excitability may be a critical feature of slow wave sleep that makes it more suitable for memory consolidation than the awake state.</p>
Impact of Marine Shipping Emissions on Ozone Pollution during the Warm Seasons in China
<ul> <li><strong>all.city.2017-01.nc: </strong>The hourly observations of six major air pollutants at 336 cities in China in 2017, including latitude and longitude information for these cities. These observations are provided by CNEMC.</li> <li><strong>china_CMAQ_appmap_no_gat.nc: </strong>The mask file for mainland China.</li> <li><strong>CMAQ_HCHO_VCDs.zip</strong>: Daily HCHO VCDs data calculated from CMAQ output and its calculation script.</li> <li><strong>conc_evaluation.zip</strong>: The code lists of the cities located in all coastal regions, BTH, YRD, and PRD region, respectively (<strong>XXXXXX_citycode.csv</strong>), the statistical results of MDA8 O3 and NO2 in these regions and corrsponding calulation scripts.</li> <li><strong>Data_era5.zip: </strong>All the ERA5 data used in the article (which have been extracted into nc files), including hourly meteorological parameters for Beijing-Tianjin-Hebei, the Yangtze River Delta, and the Pearl River Delta regions, respectively.</li> <li><strong>GRIDCRO2D_2017100100_d01:</strong></li> <li><strong>met_evaluation.zip: </strong>The information of the meteorological stations located in all coastal regions (<strong>MET_STATION_COASTAL.csv</strong>), The statistical results of T2, RH2, WS10 in these stations and corrsponding calulation scripts.</li> <li><strong>nest_vs_base_evaluation.zip: </strong>Statistical results of the simulation performance of the nested and basic experiments for April, containing mesh data for the nested inner domains, results for the models of the nested experiments, the scripts used to calculate the statistical results, and the results of the calculations.</li> <li><strong>OMIHCHOd_interpolate_data_control.nc: </strong>Daily HCHO VCDs data from OMHCHOd dataset spatially interpolated to have the same horizontal grid as the CMAQ results.</li> <li><strong>pattern_sa_polluted_clean.zip: type_stat_sa_newdef.ncl </strong>is to calculate ozone impacts of MSEs on polluted days and clean days under different weather patterns and the csv files are the results.</li> <li><strong>region_port_city.zip: </strong> The mask files for the three main regions, latitude/longitude for the 13 coastal port cities (<strong>port_city_lat_lon.csv</strong>), the results of seasonally averaged impacts of MSEs on ozone for the 3 regions and 13 cities (<strong>region_port_city_mda8o3_sa_rsa.csv</strong>), the ncl file with the same name is the script for the calculations.</li> <li><strong>sim_hourly_o3_no2_base.nc: </strong>The extracted data from the WRF-CMAQ results file, which includes modelled hourly surface ozone and NO2 concentrations for the simulation period.</li> <li><strong>sim_hourly_sa_o3_ocean_base.nc: </strong>The extracted data from the CMAQ-ISAM model simulation results and includes the hourly impact of marine shipping emissions of ozone obtained from the simulation.</li> <li><strong>T-PCA_BTH_YRD_PRD.zip: </strong>The daily weather pattern of Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (YRD), and Pearl River Delta (PRD) regions obtained by the TPC-A method of classification, with 2 to 10 categories.</li> <li><strong>CJK_domain.ncl</strong> is used to produce the manuscript’s <strong>Figure 1</strong>.</li> <li><strong>sim_obs_dis_MDA8_uv_coastal.ncl </strong>is used to produce the manuscript’s <strong>Figure 2</strong>.</li> <li><strong>absolute_dis_MDA8h.ncl </strong>is used to produce the manuscript’s <strong>Figure 3</strong>.</li> <li><strong>region_city_o3_sa.ncl </strong>is used to produce the manuscript’s <strong>Figure 4</strong>.</li> <li><strong>type_mean_slp_o3_sa.ncl </strong>is used for the distribution maps in<strong> Figures 5, 6 and 7.</strong></li> <li><strong>bar_type_sa.ncl </strong>is used to produce of the bar charts in <strong>Figure 5</strong>, <strong>Figure 6</strong> and <strong>Figure 7</strong>, which were combined with the distribution maps obtained from <strong>type_mean_slp_o3_sa.ncl.</strong></li> <li><strong>cal_FDR_PCT.ncl </strong>is used to calculate the number of pairs of indistinguishable patterns obtained based on the FDR method for different number of classifications in the three regions (<strong>Figure S1</strong>).</li> <li><strong>OMI_xhcho.ncl </strong>is used to produce <strong>Figure S2</strong> in the Supplementary Materials.</li> <li><strong>MSEs_nox_voc_dis.ncl </strong>is used to produce <strong>Figure S3 </strong>in the Supplementary Materials.</li> <li><strong>relative_dis_DA8h.ncl </strong>is used to produce <strong>Figure S4</strong> in the Supplementary Materials.</li> <li><strong>region_city_o3_sa_rc.ncl </strong>is used to produce <strong>Figure S5</strong> in the Supplementary Materials.</li> <li><strong>type_mean_slp.ncl </strong>is used to produce <strong>Figure S6</strong> in the Supplementary Materials.</li> <li><strong>type_mean_met.ncl </strong>is used to produce <strong>Figures S7-S9</strong> in the Supplementary Materials, just replace the region name in this script.</li> <li><strong>stat_season_pattern.zip </strong>includes frequency of occurrence of the four synoptic patterns during three seasons, the ncl file is the script for the calculations, and the csv file is the output (<strong>Table S1</strong>).</li> </ul>
Data from: Phenological mismatches mitigate the ecological impact of a biological invader on amphibian communities
<p>Data and code for the manuscript entitled "Phenological mismatches mitigate the ecological impact of a biological invader on amphibian communities" for Ecological Applications (2024). <br><br><br><br>The raw sequencing data was submitted to NCBI’s Sequence Read Archive (SRA) under BioProject number PRJNA1023717 (https://dataview.ncbi.nlm.nih.gov/object/PRJNA1023717?reviewer=rciv7kme2qq5vpcnqqog4vjioo). </p>
Data archive for paper "Energy and environmental impacts of air-to-air heat pumps in a mid-latitude city"
<p><strong>Overview</strong></p> <p>This is the data archive for paper "<a href="https://www.nature.com/articles/s41467-024-49836-3" target="_blank" rel="noopener">Energy and environmental impacts of air-to-air heat pumps in a mid-latitude city</a>". It contains the paper's data archive with model outputs (see <code>notebooks</code> folder) and the Singularity image for (optionally) re-running experiments.</p> <p>For the standalone models to model air conditioners and heat pumps please refer to <a href="https://github.com/dmey/minimal-dx">MinimalDX</a>.</p> <p><strong>Prerequisites</strong></p> <ul> <li>Linux with Bash shell.</li> <li><a>Git</a> version >= 2.</li> <li><a href="https://sylabs.io/">Singularity</a> version >= 3.</li> <li><a href="https://en.wikipedia.org/wiki/Portable_Batch_System">Portable Batch System</a>*.</li> <li><a href="https://en.wikipedia.org/wiki/Intel_Fortran_Compiler">Intel Fortran Compiler</a> [<em>Required for MesoNH simulations</em>].</li> <li>A compatible version of the MPI library implementation version 3 [<em>Required for MesoNH simulations</em>].</li> </ul> <p>Please note that most steps require <a href="https://sylabs.io/">Singularity</a>. If you are looking for information on how to install or use Singularity, please refer to the <a href="https://sylabs.io/docs">Singularity documentation</a>. Please note that depending on your specific system settings and resource availability, you may need to modify PBS parameters at the top of submit scripts stored in the hpc directory.</p> <p><strong>Simulations</strong></p> <p><em><strong>Offline</strong></em></p> <ol> <li>Build Surfex with <code>qsub hpc/surfex_build.pbs</code>.</li> <li>Run scenarios with the following commands: <pre><code> qsub -v case_name=fincap hpc/surfex_run.pbs qsub -v case_name=fincap_extended_autosize hpc/surfex_run.pbs qsub -v case_name=minidx_cop=2.5 hpc/surfex_run.pbs qsub -v case_name=minidx_cop=3.0 hpc/surfex_run.pbs qsub -v case_name=minidx_cop=3.5 hpc/surfex_run.pbs qsub -v case_name=minidx_cop=4.0 hpc/surfex_run.pbs<br> qsub -v case_name=minidx_cop=4.5 hpc/surfex_run.pbs </code></pre> </li> </ol> <p><em><strong>Online</strong></em></p> <p>To run MesoNH simulations, follow the three steps outlined below in the same order. Note: Depending on your system and configuration, submit scripts may require change.</p> <ol> <li>Build MesoNH with <code>qsub hpc/build_mnh_intel.pbs</code>.</li> <li>Run the preprocessing step with <code>qsub hpc/submit_mnh_prep.pbs</code>.</li> <li>Finally run MesoNH cases with the following commands for <code>fincap</code> and <code>minidx</code> simulations respectively: <pre><code> hpc/submit_mnh.sh fincap 20050120 12 1 toulouse hpc/submit_mnh.sh minidx 20050120 12 1 toulouse </code></pre> </li> <li>Post-process the results with <code>qsub hpc/submit_mnh_post.pbs</code></li> </ol> <p><strong>Analyses</strong></p> <pre><code>qsub hpc/postprocess_results.pbs # Plots in notebooks/ </code></pre>
Code&Data_'Choosing fit-for-purpose biodiversity impact indicators for agriculture in the Brazilian Cerrado ecoregion'
<p>File "R_Scripts_biodiversity_indicators.zip" includes codes for calculating the biodiversity impact on the terrestrial vertebrates of the Cerrado biome using the countryside Species Area Relationship (cSAR), the Species Threat Abatement and Restoration (STAR) metric and the Species Habitat Index (SHI).</p> <p>File "results_biodiversity_indicators.zip" includes the result tables of the calculations done with the above mentioned codes. </p>
Southern Ocean's circulation impact on the marine carbon cycle
<p>In the context of past and present climate change, the Southern Ocean (SO) has been identified as a crucial region modulating the concentration of atmospheric CO<sub>2</sub>. The sustained upwelling of carbon-rich deep waters and inefficient nutrient utilisation at the surface of SO leads to an outgassing of natural CO<sub>2</sub>, while anthropogenic CO<sub>2</sub> is entrained to depth during the formation of Antarctic Bottom water (AABW), Antarctic intermediate water (AAIW) and sub-Antarctic mode water (SAMW). Changes to the SO circulation resulting from both dynamic and buoyancy forcing can alter the rate of upwelling as well as formation and subsequent transport of AABW, AAIW and SAMW, thus impacting the air-sea CO<sub>2</sub> exchange in SO. Models of all complexity robustly show that stronger southern hemispheric (SH) westerlies enhance the SO upwelling, thus leading to stronger natural CO<sub>2</sub> outgassing, with a sensitivity of ∼0.13 GtC/yr for a 10% increase in SH westerly windstress. While the impact of changes in the position of the SH westerly winds was previously unclear, recent simulations with high-resolution ocean/sea-ice/carbon cycle models show that a poleward shift of the SH westerlies also enhances natural CO<sub>2</sub> outgassing with a sensitivity of ∼0.08GtC/yr for a 5• poleward shift. While enhanced AABW transport reduces deep ocean natural DIC concentration and increases surface natural DIC concentration, it acts on a centennial timescale. Future work should better constrain both the natural and anthropogenic carbon cycle response to changes in AABW and the compound impacts of dynamic and buoyancy changes on the SO marine carbon cycle.</p>
Dataset related to the article "Binary classification of copy number alteration profiles in liquid biopsy with potential clinical impact in advanced NSCLC"
<p>This record contains original data used in the article "Binary classification of copy number alteration profiles in liquid biopsy with potential clinical impact in advanced NSCLC" to develop a linear support vector machine (SVM) classifier to predict chromosomal instability. </p> <p>We retrospectively evaluated the results of plasma NGS analysis performed at our Institution by using the AVENIO ctDNA Expanded Kit, a panel of 77 genes, which detects the major classes of genetic alterations. Binary classification, into “stable” (SCP) or “unstable” (UCP) chromosomal profiles, was initially performed by visual inspection of individual CNV alteration profiles by two independent professionals of our group. Then we decided to implement a support vector machine (SVM) classifier to automatically classify CNV profiles as SCP or UCP, beyond operators’ experience. We considered the segmented log2 ratios (.cns) files provided by the CNV kit software and computed three features (Segments, Size, Chromosomes). An alteration (“occurrence of instability”) in the CNV profile was defined each time we found a DNA segment of any size with absolute value of the log2 copy ratio exceeding a fixed cut-off. Two different cut-off values on log2 copy ratio were examined: 0.1 and 0.2. Once the cut-off was defined, three features were considered as covariates in the SVM classifier: 1) number of altered segments (Segments), 2) total length of altered regions (Size) and 3) number of affected chromosomes (Chromosomes).</p> <p>The “dataset_0.1.txt” and “dataset_0.2.txt” files are the original data matrices obtained by considering a cut-off of 0.1 and 0.2, respectively, on the absolute value of the log2 copy ratio.</p> <p>Rows represent available samples in our study (n=177). Columns contain the following variables: anonymized sample IDs (Sample), the class, “stable” or “unstable”, as assigned by two independent professionals of our group (Class), the corresponding binary label (Label: 0 for “stable”, 1 for “unstable”), the three features used as covariates in the SVM classifier and computed as described above (Segments, Size, Chromosomes).</p> <p><br>For the detailed results of our work, please refer to the full article.</p>
Are rice fields less diverse and more invaded by non-native species than less impacted habitats? A test with wetland microcrustaceans
<p>Raw data of environmental variables and microcrustacean abundance community matrix</p> <p>R scripts used in the study</p>
Data presented in Dupont et al. 2024 "Impact of dust source patchiness on the existence of a constant dust flux layer during aeolian erosion events"
<p>Meteorological and dust data used in Dupont et al. 2024. Data are based on measurements recorded above two erosive surfaces from two very different desert regions, one at a high-latitude location in Iceland and the other at a low-latitude location in Jordan. The Iceland campaign was co-organized by two projects: FRAGMENT (FRontiers in dust minerAloGical coMposition and its Effects upoN climaTe) and HiLDA (Iceland as a model for high-latitude dust sources – a combined experimental and <br>modeling approach for characterization of dust emission and transport processes); and the Jordan campaign (J-WADI: Jordan Wind erosion And Dust Investigation) was co-organized by the FRAGMENT and Helmholtz Young Investigator Group ``A big unknown in the climate impact of atmospheric aerosol: Mineral soil dust'' projects.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.