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829
datasets available to search
ShareScore release 0.9.0
Dataset results
829 results for “Drug resistance”
Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases
ClinicalTrials.gov study NCT02803437. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy
ClinicalTrials.gov study NCT00552526. IPD Sharing: Not stated. Countries: 1. Publications: 6.
The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients
ClinicalTrials.gov study NCT05958069. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study
ClinicalTrials.gov study NCT02731300. IPD Sharing: NO. Countries: 0. Publications: 1.
Chromosomal Instability as a Surrogate Biomarker of Drug Resistance in Immunotherapy for Lung Cancer Patients
ClinicalTrials.gov study NCT04203095. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
Effects of Renal Sympathetic Denervation on the Cardiac and Renal Functions in Patients With Drug-resistant Hypertension Through MRI Evaluation
ClinicalTrials.gov study NCT02164435. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Multi-Drug Resistant Tuberculosis in Korea
ClinicalTrials.gov study NCT00341601. IPD Sharing: Not stated. Countries: 1. Publications: 7.
The Safety and Efficacy of BDL(Bedaquiline Plus Delamanid Plus Linezolid) Regimen in Subjects With Pulmonary Infection of Multi-drug Resistant Tuberculosis (MDR-TB) or Rifampicin-Resistant Tuberculosi
ClinicalTrials.gov study NCT06476210. IPD Sharing: Not stated. Countries: 1. Publications: 15.
Monitoring Pregnant Women for Antimalarial Drug Resistance
ClinicalTrials.gov study NCT05072613. IPD Sharing: NO. Countries: 1. Publications: 5.
Verification of the Efficacy and Safety of the BAROSTIM NEO System in the Treatment of Drug Resistant Hypertension
ClinicalTrials.gov study NCT01471834. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Data from: Delays and loss to follow up before treatment of drug-resistant TB following implementation of Xpert MTB/RIF in South Africa: a retrospective cohort study
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Data from: Cholera outbreaks (2012) in three districts of Nepal reveal clonal transmission of multi-drug resistant Vibrio cholerae O1
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Amphibian resistance to chytridiomycosis increases following low virulence chytrid fungal infection or drug-mediated clearance
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Data from: Assessment of markers of antimalarial drug resistance in Plasmodium falciparum isolates from pregnant women in Lagos, Nigeria
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Data from: Transmission of multidrug-resistant and drug-susceptible tuberculosis within households: a prospective cohort study
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Data from: Performance of TaqMan Array Card to detect TB drug resistance on direct specimens
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Data from: A case of Hashimoto’s thyroiditis with multiple drug resistance and high expression of efflux transporters
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Data from: Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients
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Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria
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Data from: Aggressive chemotherapy and the selection of drug resistant pathogens
Drug resistant pathogens are one of the key public health challenges of the 21st century. There is a widespread belief that resistance is best managed by using drugs to rapidly eliminate target pathogens from patients so as to minimize the probability that pathogens acquire resistance de novo. Yet strong drug pressure imposes intense selection in favor of resistance through alleviation of competition with wild-type populations. Aggressive chemotherapy thus generates opposing evolutionary forces which together determine the rate of drug resistance emergence. Identifying treatment regimens which best retard resistance evolution while maximizing health gains and minimizing disease transmission requires empirical analysis of resistance evolution in vivo in conjunction with measures of clinical outcomes and infectiousness. Using rodent malaria in laboratory mice, we found that less aggressive chemotherapeutic regimens substantially reduced the probability of onward transmission of resistance (by >150-fold), without compromising health outcomes. Our experiments suggest that there may be cases where resistance evolution can be managed more effectively with treatment regimens other than those which reduce pathogen burdens as fast as possible.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.