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991 results for “Inflammatory response”
Figure 1 from: Nafisah W, Dalilati AZ, Christina YI, Atho'illah MF, Rifa'ia M, Noor TNETA, Nugraha AP (2024) Amstirdam coffee ameliorates Lp-PLA2 and the inflammatory response in an atherosclerosis rats. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e106817
Figure 1 Reduction of Lp-PLA2 production after ACE treatment in mice fed a high-fat, high-fructose diet. The expression of Lp-PLA2 production in mice fed with HFFD and administered ACE was determined from flow cytometry analysis (Fig. 1A). The percentage of Lp-PLA2 production in mice fed with HFFD and administered ACE The data are mean SD (n = 5). N: normal-fed mice (non-high-fat-fructose diet); HFFD: high-fat-fructose diet mice (w/o administration of ACE); D1: HFFD mice receiving ACE 104 mg/kg body weight; D2: HFFD mice receiving ACE 520 mg/gram BW; D3: HFFD mice receiving ACE 5200 mg/kg BW. The different notation on the chart was considered significantly different for each group at p< 0.05 and vice versa on the DMRT post hoc test.
Figure 4 from: Nafisah W, Dalilati AZ, Christina YI, Atho'illah MF, Rifa'ia M, Noor TNETA, Nugraha AP (2024) Amstirdam coffee ameliorates Lp-PLA2 and the inflammatory response in an atherosclerosis rats. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e106817
Figure 4 Administration of ACE increased IL-10 production (CD4+IL-10+) in mice fed with a high-fat, high-fructose diet for 5 months. The expression of CD4+IL-10+ in mice fed with HFFD and administered ACE was determined by flow cytometry analysis (Fig. 4E). The percentage of regulatory cells (CD4+IL-10+) in mice fed with HFFD and administered ACE (Fig. 4F) The data are mean SD (n = 5). N: normal-fed mice (non-high-fat-fructose diet); HFFD: high-fat-fructose diet mice (w/o administration of ACE); D1: HFFD mice receiving ACE 104 mg/kg body weight; D2: HFFD mice receiving ACE 520 mg/kg body weight; D3: HFFD mice receiving ACE 5200 mg/kg body weight. The different notation on the chart was considered significantly different for each group at p < 0.05 and vice versa on the DMRT pos hoc test.
Aconitate Decarboxylase 1 Mediates the Acute Airway Inflammatory Response to Environmental Exposures
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ASSESSMENT OF SYSTEMIC INFLAMMATORY RESPONSE IN PATIENTS WITH ACUTE ACETIC ACID POISONING
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Evaluation of the host inflammatory response with electroacupuncture as an adjunct to nonsurgical periodontal therapy
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Evaluation of the host inflammatory response with electroacupuncture as an adjunct to nonsurgical periodontal therapy
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Data from: A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP
Antimicrobial peptides (AMPs) are one of the most important defense mechanisms against bacterial infections in insects, plants, non-mammalian vertebrates, and mammals. In the present study, a class of synthetic AMPs was evaluated for anti-inflammatory activity. One cationic AMP, GW-A2, demonstrated the ability to inhibit the expression levels of nitric oxide (NO), inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in lipopolysaccharide (LPS)-activated macrophages. GW-A2 reduced LPS-induced increases in the phosphorylation of mitogen-activated protein kinase and protein kinase C-α/δ and the activation of NF-κB. GW-A2 also inhibited NLRP3 inflammasome activation induced by LPS and ATP. Furthermore, in the mice injected with LPS, GW-A2 reduced (1) the concentration of IL-1β, IL-6 and TNF-α in the serum; (2) the concentration of TNF-α in the peritoneal lavage; (3) the expression levels of iNOS, COX-2 and NLRP3 in the liver and lung; (4) the infiltration of polymorphonuclear neutrophils in the liver and lung. The underlying mechanisms for the anti-inflammatory activity of GW-A2 were found to be partially due to LPS and ATP neutralization. These results provide insights into how GW-A2 inhibits inflammation and the NLRP3 inflammasome and provide a foundation for the design of rational therapeutics for inflammation-related diseases.
Effect of Celecoxib on Perioperative Inflammatory Response in Colon Cancer
ClinicalTrials.gov study NCT01284504. IPD Sharing: NO. Countries: 1. Publications: 0.
Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences
ClinicalTrials.gov study NCT02529592. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Inflammatory Response and Gingival iNOS Levels in Diabetic vs. Non-Diabetic Periodontitis Patients
ClinicalTrials.gov study NCT06803836. IPD Sharing: NO. Countries: 1. Publications: 0.
Hyporesponsiveness of Natural Killer Cells and a Dysfunctional Inflammatory Response in Critically Ill Patients
ClinicalTrials.gov study NCT02565589. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effect of Anti-Inflammatory Agents on Biological Responses to Endotoxin Inhalation in Healthy Subjects
ClinicalTrials.gov study NCT02252809. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)
ClinicalTrials.gov study NCT04109807. IPD Sharing: YES. Countries: 1. Publications: 0.
Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.
ClinicalTrials.gov study NCT01377441. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Predicting Inflammatory Skin Disease Response to IL-23 Blockade
ClinicalTrials.gov study NCT04541329. IPD Sharing: NO. Countries: 1. Publications: 0.
Pembrolizumab in Treating Patients With Hormone Receptor Positive, Localized Inflammatory Breast Cancer Who Are Receiving Hormone Therapy and Did Not Achieve a Pathological Complete Response to Chemot
ClinicalTrials.gov study NCT02971748. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Inflammatory Response to Aortic Valve Replacement
ClinicalTrials.gov study NCT03074838. IPD Sharing: NO. Countries: 0. Publications: 1.
A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel
ClinicalTrials.gov study NCT04215146. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Prevelance of Axial Spondylosis Arthritis in Inflammatory Bowel Disease and Its RESPONSE to Tumour Necrosis Factor (TNF) Inhibitors Treatment in Assiut University Hospital
ClinicalTrials.gov study NCT06601595. IPD Sharing: UNDECIDED. Countries: 0. Publications: 10.
Hormonal and Inflammatory Biomarkers and Response to Cognitive Remediation in Recent-onset Psychosis
ClinicalTrials.gov study NCT04418570. IPD Sharing: NO. Countries: 0. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.