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897 results for “Therapeutic targets”

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geo24/100

Contrasting stage-dependent requirements during AML evolution identify EZH2 as a therapeutic target in AML

GEO Series GSE112724. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMar 2019View details →
geo24/100

Transcription factor ZNF263 enhances EGFR-targeted therapeutic response and reduces residual disease in lung adenocarcinoma [RNAseq2]

GEO Series GSE253742. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo24/100

Mucosal Single-Cell Profiling of Crohn's-Like Disease of the Pouch Reveals Unique Pathogenesis and Therapeutic Targets

GEO Series GSE246987. Homo sapiens. 59 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenAug 2024View details →
geo24/100

DNAPKCs as a therapeutic target in small cell lung cancer

GEO Series GSE273409. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

Identification and Characterization of a MAPT-targeting Locked Nucleic Acid Antisense Oligonucleotide Therapeutic for Tauopathies II

GEO Series GSE204931. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma [microarray]

GEO Series GSE123409. Mus musculus. 7 samples. Type: Expression profiling by array; Third-party reanalysis.

openGEO-OpenDec 2018View details →
geo24/100

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting

GEO Series GSE56369. Homo sapiens. 25 samples. Type: Expression profiling by array.

openGEO-OpenApr 2014View details →
geo24/100

Macrophage transcriptional profile identifies lipid catabolic pathways that can be therapeutically targeted after spinal cord injury

GEO Series GSE84737. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2017View details →
geo24/100

Cross-Species Approach Identifies MELK as a Potential Therapeutic Target in Prostate Cancer

GEO Series GSE101539. Homo sapiens; Mus musculus. 120 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2018View details →
geo24/100

Selective therapeutic targeting of the first and second bromodomains of the BET proteins in cancer and immuno-inflammation [RNA-seq]

GEO Series GSE138089. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2020View details →
geo24/100

DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma [RNA-seq]

GEO Series GSE209812. Mus musculus; Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo24/100

Genome-wide flow sorting CRISPRi screen identify PTGES3 as a novel therapeutic target of AR [ATAC-seq]

GEO Series GSE180034. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3 [RRBS]

GEO Series GSE216050. Homo sapiens. 6 samples. Type: Methylation profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3 [22Rv1sgCD276]

GEO Series GSE216712. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Illumina]

GEO Series GSE98987. Homo sapiens. 23 samples. Type: Expression profiling by array.

openGEO-OpenMay 2020View details →
geo24/100

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

GEO Series GSE117970. Homo sapiens. 116 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2019View details →
geo24/100

RNA decay defines the therapeutic response to transcriptional perturbation in leukemia [SLAMseq K562 RNAPII targeting]

GEO Series GSE229303. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2023View details →
geo24/100

An unbiased lncRNAs dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a potential therapeutic target for Multiple Myeloma

GEO Series GSE273796. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Genome-wide flow sorting CRISPRi screen identify PTGES3 as a novel therapeutic target of AR

GEO Series GSE292612. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

Indisulam targets RNA splicing and metabolism to serve as a novel therapeutic strategy for high risk neuroblastoma

GEO Series GSE160446. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2021View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record