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467 results for “Trial Data”
Chinook salmon digestion data within predatory largemouth bass and channel catfish through controlled feed trials
<p>Diet analysis is a vital tool for understanding trophic interactions and is frequently used to inform conservation and management. Molecular approaches can identify diet items that are impossible to distinguish using more traditional visual-based methods. Yet, our understanding of how different variables, such as predator species or prey ration size, influence molecular diet analysis is still incomplete. Here, we conducted a large feeding trial to assess the impact that ration size, predator species, and temperature had on digestion rates estimated with visual identification, qPCR, and metabarcoding. Our trial was conducted by feeding two rations of Chinook salmon (Oncorhynchus tshawytscha) to two piscivorous fish species (largemouth bass (Micropterus salmoides)) and channel catfish (Ictalurus punctatus)) held at two different temperatures (15.5°C and 18.5°C) and sacrificed at regular intervals up to 120 hours from the time of ingestion to quantify the prey contents remaining in the digestive tract. We found that ration size, temperature, and predator species all influenced digestion rate, with some indication that ration size had the largest influence. DNA based analyses were able to identify salmon smolt prey in predator gut samples for much longer than visual analysis (~12 hours for visual analysis versus ~72 hours for molecular analyses). Our study provides evidence that modeling the persistence of prey DNA in predator guts for molecular diet analyses may be feasible using a small set of controlling variables for many fish systems.</p>
Data from: Identifying and overcoming breastfeeding challenges using two-way short message service, a randomized controlled trial
<p>Breastfeeding challenges, such as pain and perception of insufficient milk supply, prevent many women from exclusively breastfeeding their babies for the six-month duration recommended by the World Health Organization. Mobile health strategies may help women identify and overcome breastfeeding challenges. This study evaluated a two-way short message service (SMS) intervention that delivered breastfeeding messages to women in Kiambu County, Kenya, and its impact on rates of exclusive breastfeeding and breastfeeding behavior at 1, 4, and 6 months post-delivery. Women in the control group received a general package of messages containing postnatal information; women in the intervention group received these messages, plus messages related to breastfeeding and surveys which offered more information about breastfeeding challenges. Both groups of women had access to a help desk agent who responded to questions via SMS.</p> <p>There was no significant difference in the rate of exclusive breastfeeding between the intervention and control at any time point (p=.861). Women in the intervention group were more likely to report experiencing breastfeeding challenges such as pain and perceived insufficient milk supply than those in the control group (32% vs. 24%, p=0.00). Of the women in the intervention group who reported experiencing breastfeeding challenges, 70% of them found a resolution to their challenge, and 23% of them resolved their challenges using SMS. SMS may help women in low-resource settings to identify and overcome their breastfeeding challenges.</p>
Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT06914102. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prediction of the SEPRA Diabetes Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT05577728. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Long-Term Data Collection From Participants in Adult AIDS Clinical Trials
ClinicalTrials.gov study NCT00001137. IPD Sharing: Not stated. Countries: 2. Publications: 13.
Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT04736693. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Simulated and Synthetic Health Data: Improving Clinical Research on Rare Diseases. A Real-World Data Simulation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Trials. A Retrospective, Observa
ClinicalTrials.gov study NCT07016282. IPD Sharing: NO. Countries: 2. Publications: 27.
Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT07088718. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
ClinicalTrials.gov study NCT04067297. IPD Sharing: NO. Countries: 1. Publications: 4.
A Remote, 9-week Insomnia Treatment Trial to Collect Real World Data for a Digital Therapeutic
ClinicalTrials.gov study NCT04325464. IPD Sharing: NO. Countries: 1. Publications: 2.
Do Fair Comparisons or Harms Data Increase Responsiveness to Feedback About Antibiotic Prescribing: 2x2 Factorial Trial
ClinicalTrials.gov study NCT04594200. IPD Sharing: NO. Countries: 1. Publications: 4.
Prediction of the COBRRA VTE Anticoagulant Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT05264168. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Replication of the TRITON-TIMI Antiplatelet Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT04237922. IPD Sharing: Not stated. Countries: 1. Publications: 1.
PRISM: The PRimary Care Individual Social Norms MSK Data Dashboard: a Feasibility Trial
ClinicalTrials.gov study NCT07112508. IPD Sharing: NO. Countries: 0. Publications: 10.
Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT06914154. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Desktop Versus Mobile Data Collection in Clinical Trial
ClinicalTrials.gov study NCT01473238. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data-driven Quality Improvement in Primary Care - Trial
ClinicalTrials.gov study NCT01425502. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
The Surgical Education Culture Optimization Through Targeted Interventions Based on National Comparative Data - "The SECOND Trial"
ClinicalTrials.gov study NCT03739723. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Replication of the PLATO Antiplatelet Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT04237935. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: A critical appraisal of clinical trials conducted and subsequent drug approvals in India and South Africa
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Allen Brain Atlas
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International Brain Laboratory public data
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OpenNeuro
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