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ShareScore release 0.9.0
Dataset results
174 results for “cardiac control”
Effectiveness of Tai Chi on Cardiac Autonomic Function and Symptomatology in Women With Fibromyalgia: a Randomized Controlled Trial
ClinicalTrials.gov study NCT03016585. IPD Sharing: Not stated. Countries: 0. Publications: 0.
A HAND2 Cistrome Controls Heart Development and the Endothelial-Mesenchymal Transition during Cardiac Valve Formation
GEO Series GSE73368. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Two Forkhead transcription factors regulate cardiac progenitor specification by controlling the expression of receptors of the fibroblast growth factor and Wnt signaling pathways
GEO Series GSE65439. Drosophila melanogaster. 9 samples. Type: Expression profiling by array.
Activation of imprinted gene Pw1 promotes cardiac fibrosis after ischemic injury [control_and_Pw1 CKO]
GEO Series GSE232326. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Functional architecture of cardiac TF regulatory landscapes in control of mammalian heart development
GEO Series GSE318090. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-Sequencing analysis of control and SORBS2 knockdown cardiac progenitor cells derived from human stem cells in vitro
GEO Series GSE137090. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
BulkRNA Sequencing of human induced pluripotent stem cells derived cardiac progenitors (hiPSC-CPs) from healthy control, tetralogy of Fallot (TOF) patients with DiGeorge Syndrome (DG) and without DiGe
GEO Series GSE196578. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
JAK Activity Regulates Mesoderm Cell Fate and Cardiac Differentiation by controlling MESP1 expression
GEO Series GSE262452. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Cardiac aldosterone regulated genes in mice with cardiomyocytes targeted mineralocorticoid receptor overexpression (MR-Cardio mice) and their controls (Ctrl mice)
GEO Series GSE34049. Mus musculus. 23 samples. Type: Expression profiling by array.
Tiered Sympathetic Control of Cardiac Function Revealed by Viral Tracing and Single Cell Transcriptome Profiling
GEO Series GSE231924. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
The ACTonHEART Study: a Randomized Controlled Clinical Trial of a short intervention based on Acceptance and Commitment Therapy vs. usual care for cardiac rehabilitation patients with coronary heart disease.
<p>The ACTonHEART study evaluates the effectiveness of adding an ACT-based intervention to usual secondary prevention care of coronary heart disease, in order to promote healthy lifestyle changes and improve psychological wellbeing and quality of life among CR patients; psychological flexibility was a hypothesized mechanism of change.</p> <p>Ninety-two patients were enrolled and randomized, following an unbalanced randomization ratio of 2:1, to the ACT group (N= 59) and the control group (N= 33). The control group completed standard CR (Usual Care; UC) and the experimental subjects participated in the ACTonHEART group intervention in addition to standard CR. The ACTonHEART intervention consisted of three, two-hour, group sessions, focused on integrating acceptance and mindfulness skills into educational topics on heart-healthy behaviors. The primary study hypothesis is that the ACTonHEART group is superior to the UC group in the following primary outcome measures: LDL-cholesterol, resting systolic blood pressure, body mass index, and psychological wellbeing.</p> <p>Participants were assessed at baseline and at the end of the rehabilitation period. Linear mixed models analyses were used to detect the group x time interaction. Across all outcome variables, no time x treatment effect was found. The results of this study may inform the future implementations of ACT in the cardiac rehabilitation context.</p> <p>Corresponding author: Chiara Spatola (chiara.spatola@unime.it)</p>
Cardiac aldosterone and corticosterone regulated genes in mice with cardiomyocytes targeted mineralocorticoid receptor overexpression (MR-Cardio mice) and their controls (Ctrl mice)
GEO Series GSE33022. Mus musculus. 34 samples. Type: Expression profiling by array.
Data set from De Maria B, Bari V, Sgoifo A, Carnevali L, Cairo B, Vaini E, Catai AM, de Medeiros Takahashi AC, Dalla Vecchia LA, Porta A. Concomitant Evaluation of Heart Period and QT Interval Variability Spectral Markers to Typify Cardiac Control in Humans and Rats. Front Physiol. 2019 Nov 29;10:1478. doi: 10.3389/fphys.2019.01478. PMID: 31849718; PMCID: PMC6897045.
<p>Data set from De Maria B, Bari V, Sgoifo A, Carnevali L, Cairo B, Vaini E, Catai AM, de Medeiros Takahashi AC, Dalla Vecchia LA, Porta A. Concomitant Evaluation of Heart Period and QT Interval Variability Spectral Markers to Typify Cardiac Control in Humans and Rats. Front Physiol. 2019 Nov 29;10:1478. doi: 10.3389/fphys.2019.01478. PMID: 31849718; PMCID: PMC6897045.</p> <p> </p> <p>This is the abstract:</p> <p>The variability of heart period, measured as the time distance between two consecutive QRS complexes from the electrocardiogram (RR), was exploited to infer cardiac vagal control, while the variability of the duration of the electrical activity of the heart, measured as the time interval from Q-wave onset to T-wave end (QT), was proposed as an indirect index of cardiac sympathetic modulation. This study tests the utility of the concomitant evaluation of RR variability (RRV) and QT variability (QTV) markers in typifying cardiac autonomic control of humans under different experimental conditions and of rat groups featuring documented differences in resting sympatho-vagal balance. We considered: (i) 23 healthy young subjects in resting supine position (REST) undergoing head-up tilt at 45° (T45) and 90° (T90) followed by recovery to the supine position; (ii) 9 Wistar (WI) and 14 wild-type Groningen (WT) rats in unstressed conditions, where the WT animals were classified as non-aggressive (non-AGG, <em>n</em> = 9) and aggressive (AGG, <em>n</em> = 5) according to the resident intruder test. In humans, spectral analysis of RRV and QTV was performed over a single stationary sequence of 250 consecutive values. In rats, spectral analysis was iterated over 10-min recordings with a frame length of 250 beats with 80% overlap and the median of the distribution of the spectral markers was extracted. Over RRV and QTV we computed the power in the low frequency (LF, from 0.04 to 0.15 Hz in humans and from 0.2 to 0.75 Hz in rats) band (LF<sub>RR</sub> and LF<sub>QT</sub>) and the power in the high frequency (HF, from 0.15 to 0.5 Hz in humans and from 0.75 to 2.5 Hz in rats) band (HF<sub>RR</sub> and HF<sub>QT</sub>). In humans the HF<sub>RR</sub> power was lower during T90 and higher during recovery compared to REST, while the LF<sub>QT</sub> power was higher during T90. In rats the HF<sub>RR</sub> power was lower in WT rats compared to WI rats and the LF<sub>QT</sub> power was higher in AGG than in non-AGG animals. We concluded that RRV and QTV provide complementary information in describing the functioning of vagal and sympathetic limbs of the autonomic nervous system in humans and rats.</p> <p> </p>
Data set from Barbic F, Minonzio M, Cairo B, Shiffer D, Dipasquale A, Cerina L, Vatteroni A, Urechie V, Verzeletti P, Badilini F, Vaglio M, Iatrino R, Porta A, Santambrogio M, Gatti R, Furlan R. Effects of different classroom temperatures on cardiac autonomic control and cognitive performances in undergraduate students. Physiol Meas. 2019 Jun 4;40(5):054005. doi: 10.1088/1361-6579/ab1816. PMID: 30970334.
<p>Data set from Barbic F, Minonzio M, Cairo B, Shiffer D, Dipasquale A, Cerina L, Vatteroni A, Urechie V, Verzeletti P, Badilini F, Vaglio M, Iatrino R, Porta A, Santambrogio M, Gatti R, Furlan R. Effects of different classroom temperatures on cardiac autonomic control and cognitive performances in undergraduate students. Physiol Meas. 2019 Jun 4;40(5):054005. doi: 10.1088/1361-6579/ab1816. PMID: 30970334.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Objective: </strong> Indoor microclimate may affect students' wellbeing, cardiac autonomic control and cognitive performance with potential impact on learning capabilities. To assess the effects of classroom temperature variations on the autonomic profile and students' cognitive capabilities.</p> <p><strong>Approach: </strong> Twenty students attending Humanitas University School, (14M, age 21 ± 3 years) underwent a single-lead ECG continuous recording by a portable device during a 2 h lecture when classroom temperature was set 'neutral' (20 °C-22 °C, Day 1) and when classroom temperature was set to 24 °C-26 °C (Day 2). ECGs were sent by telemetry to a server for off-line analysis. Spectral analysis of RR variability provided indices of cardiac sympathetic (LF<sub>nu</sub>), vagal (HF, HF<sub>nu</sub>) and cardiac sympatho-vagal modulation (LF/HF). Symbolic analysis of RR variability provided the percentage of sequences of three heart periods with no significant change in RR interval (0V%) and with two significant variations (2V%) reflecting cardiac sympathetic and vagal modulation, respectively. Students' cognitive performance (memory, verbal comprehension and reasoning) was assessed at the end of each lecture using the Cambridge Brain Sciences cognitive evaluation tool.</p> <p><strong>Main results: </strong> Classroom temperature and CO<sub>2</sub> were assessed every 5 min. Classroom temperatures were 22.4 °C ± 0.1 °C (Day 1) and 26.2 °C ± 0.1 °C (Day 2). Student's thermal comfort was lower during Day 2 compared to Day 1. HR, LF/HF and 0V% were greater during Day 2 (79.5 ± 12.1 bpm, 6.9 ± 7.1 and 32.8% ± 10.3%) than during Day 1 (72.6 ± 10.8 bpm, 3.4 ± 3.7, 21.4% ± 9.2%). Conversely, 2V% was lower during Day 2 (23.1% ± 8.1%) than during Day 1 (32.3% ± 11.4%). Short-term memory, verbal ability and the overall cognitive C-score scores were lower during Day 2 (10.3 ± 0.3; 8.1 ± 1.2 and 10.9 ± 2.0) compared to Day 1 (11.7 ± 2.1; 10.7 ± 1.7 and 12.6 ± 1.8).</p> <p><strong>Significance: </strong> During Day 2, a shift of the cardiac autonomic control towards a sympathetic predominance was observed compared to Day 1, in the presence of greater thermal discomfort. Furthermore, during Day 2 reduced cognitive performances were found.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.