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361
datasets available to search
ShareScore release 0.9.0
Dataset results
361 results for “derived response”
Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder
GEO Series GSE210206. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Using human urinary-derived renal epithelial cells for deep phenotyping of NPHP1 deletion and determining personalised response to novel therapeutics
GEO Series GSE301183. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Comparison of the response to bile of Lactobacillus casei BL23 and its derivative strain TC01
GEO Series GSE25448. Lacticaseibacillus casei; Lacticaseibacillus paracasei ATCC 334. 12 samples. Type: Expression profiling by array.
Vascularized immunocompetent patient-derived tumor model to predict treatment response for lung cancer patients
GEO Series GSE240662. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Tumor-derived RAC1A159V mutation promotes an immunosuppressive tumor microenvironment that represses response to immune checkpoint inhibitor [RNA-Seq]
GEO Series GSE298273. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Novel human-derived RET fusion NSCLC cell lines have heterogeneous responses to RET inhibitors and differential regulation of downstream signaling
GEO Series GSE168526. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Reversal of age-related deficits in skeletal muscle during disuse and recovery in response to treatment with a secrotome product derived from partially differentiated human pluripotent stem cells
GEO Series GSE165110. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Data from: Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses
Pantoea agglomerans (P. agglomerans) is a Gram-negative bacterium that grows symbiotically with various edible plants, and the oral or sublingual administration of lipopolysaccharide derived from P. agglomerans (LPSp) have been suggested to contribute to prevention of immune-related diseases. Our previous study indicated that orally administered LPSp was shown to exhibit an LDL-lowering effect in hyperlipidemic volunteers; however, a preventive effect of LPSp on atherosclerosis is unclear. The present study attempted to evaluate the anti-atherosclerotic effect by LPSp in a mouse model of high-fat diet (HFD)-induced atherosclerosis. For 16 weeks, apoE-deficient mice were fed an HFD and received drinking water containing LPSp (0.3 or 1 mg/kg body weight/day). The results showed that the orally administered LPSp decreased body weight. A significant reduction in atherosclerotic plaque deposition was observed even with the lower dose of LPSp. The biochemical analyses showed that LPSp markedly improved glucose tolerance and reduced plasma LDL and oxidized LDL levels. In addition, LPSp significantly reduced the production of pro-inflammatory mediators including MCP-1 (in the plasma), TNF-α and IL-6 (in the colon), and decreased the oxidative burst activities in the peripheral blood sample. Taken together, these results suggest the possibility that oral administration of LPSp can effectively ameliorate HFD-induced hyperlipidemia and inflammatory/oxidative responses to prevent atherosclerosis and related metabolic disorders.
Patient-derived Organoid Model and Circulating Tumor Cells for Treatment Response of Lung Cancer
ClinicalTrials.gov study NCT03655015. IPD Sharing: NO. Countries: 1. Publications: 0.
Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer
ClinicalTrials.gov study NCT02247037. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Investigation of Microbiome-Derived Metabolite Production in Response to a Mediterranean Diet
ClinicalTrials.gov study NCT03783260. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients.
ClinicalTrials.gov study NCT02741622. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety
ClinicalTrials.gov study NCT07058324. IPD Sharing: NO. Countries: 1. Publications: 0.
Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host
ClinicalTrials.gov study NCT02732860. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Observe the Change in Microbiome in Human Derived Sample and the Relation With Clinical Response Before and After the Anti-TNF Treatment in IBD Patients
ClinicalTrials.gov study NCT03264690. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Multicenter Prospective Observational Study to Derive and Verify the Performance of a Host-response Based Diagnostic Tool for Early Detection of Severe Infections.
ClinicalTrials.gov study NCT06665542. IPD Sharing: NO. Countries: 2. Publications: 0.
Cetuximab Sensitivity Correlation Between Patient-Derived Organoids and Clinical Response in Colon Cancer Patients.
ClinicalTrials.gov study NCT04906733. IPD Sharing: NO. Countries: 1. Publications: 0.
Prediction of the Response to Neoadjuvant Radiation Chemotherapy Through Texture Analysis Derived From Medical Imaging
ClinicalTrials.gov study NCT04920435. IPD Sharing: YES. Countries: 1. Publications: 0.
Image-derived Prediction of Response to Chemo-radiation in Glioblastoma
ClinicalTrials.gov study NCT02329795. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effects of Cricket- and Beef-derived Protein on Plasma Amino Acid Concentrations and Appetite Responses
ClinicalTrials.gov study NCT04719429. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.