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2,992 results for “influenza”
Supporting data and code for: Phylogenetic identification of influenza virus candidates for seasonal vaccines
<p>The seasonal influenza (flu) vaccine is designed to protect against those influenza viruses predicted to circulate during the upcoming flu season, but identifying which viruses are likely to circulate is challenging. We use features from phylogenetic trees reconstructed from hemagglutinin (HA) and neuraminidase (NA) sequences, together with a support vector machine, to predict future circulation. We obtain accuracies of 0.75–0.89 (Area under the curve AUC 0.83–0.91) over 2016–2020. We explore ways to select potential candidates for a seasonal vaccine and find that the machine learning model has a moderate ability to select strains that are close to future populations. However, consensus sequences among the most recent three years also do well at this task. We identify similar candidate strains to those proposed by the World Health Organization, suggesting that this approach can help inform vaccine strain selection.</p>
Data complementing the Avian influenza overview April- June 2023
<p>Annex A – Data on wild bird species and HPAI detections in birds</p> <p>The annex contains tables and figures on wild bird species and HPAI virus detections in birds.</p> <p>Annex B – Applied prevention and control measures on avian influenza</p> <p>The annex contains an overview of specific prevention and control measures applied in Czechia, Denmark, Hungary, Italy and Poland from 4 April to 9 June 2023 in relation to avian influenza outbreaks in poultry and in wild birds. In addition, the overview of specific prevention and control measures applied in Poland from 27 February to 3 April that were not included in the previous published report; this information is also included in Annex B.</p> <p>Annex C – Characteristics of the HPAI A(H5Nx)-positive poultry establishments</p> <p>The Annex contains table with the characteristics of the HPAI A(H5Nx)-positive poultry establishments by affected EU Member State from 4 April to 9 June 2023. In addition, Germany and Poland reported on the characteristics of the HPAI A(H5Nx)-positive poultry establishments affected between 27 February and 3 April that were not included in the previous published report; this information is also included in Annex C.</p> <p>Annex D- Data on virus sequences</p> <p>The annex contains information on authors, originating and submitting laboratories of the sequences from GISAID’s EpiFlu™ Database on which this research is based. All submitters of data may be contacted directly via <a href="https://www.gisaid.org.">www.gisaid.org.</a></p> <p> </p>
ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid condensates - MAIN FIGURES
<p>Metadata for the manuscript entitled "ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid inclusions" - MAIN FIGURES</p>
Limited outbreak of highly pathogenic influenza A(H5N1) virus in a Herring Gull colony, Canada, 2022
<p class="MsoNormal">In summer 2022, highly pathogenic influenza A(H5N1) virus reached the Herring Gull (<em>Larus argentatus</em>) breeding colony on Kent Island, New Brunswick, Canada. Real-time monitoring revealed a self-limiting outbreak with low mortality. Proactive seabird surveillance is crucial for monitoring such limited outbreaks, protecting vulnerable seabirds, and tracing potential zoonotic transmission routes.</p>
A Phase 2 Influenza A Challenge Study Following Oral Administration of an H1N1 HA Ad-Vector Seasonal Flu Vaccine
ClinicalTrials.gov study NCT02918006. IPD Sharing: NO. Countries: 1. Publications: 2.
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Study
ClinicalTrials.gov study NCT01737710. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Immunogenicity and Safety Study of a GlaxoSmithKline Biologicals' Candidate Influenza Vaccine in Healthy Children
ClinicalTrials.gov study NCT00985790. IPD Sharing: YES. Countries: 1. Publications: 1.
A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Children
ClinicalTrials.gov study NCT00940108. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety Study of CSL Limited's Influenza Virus Vaccine in the Paediatric Population Aged >= 6 Months to < 18 Years
ClinicalTrials.gov study NCT00825162. IPD Sharing: Not stated. Countries: 1. Publications: 1.
High Dose Influenza Vaccine in Nursing Home - Pilot Study
ClinicalTrials.gov study NCT01720277. IPD Sharing: NO. Countries: 1. Publications: 12.
Safety and Immunogenicity of the Bris10 M2SR and Sing2016 M2SR H3N2 Monovalent Influenza Vaccines
ClinicalTrials.gov study NCT03999554. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Nasal-spraying LiveSpo Navax in Treatment of Influenza Virus in Children
ClinicalTrials.gov study NCT05378022. IPD Sharing: YES. Countries: 1. Publications: 29.
Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing IN Gammopathy Patients
ClinicalTrials.gov study NCT02566265. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immunogenicity of GSK Biologicals' Pandemic Influenza Vaccine (GSK1562902A) at Different Boosting Vaccination Schedules
ClinicalTrials.gov study NCT00652743. IPD Sharing: YES. Countries: 4. Publications: 1.
Safety, Tolerability, and Immunogenicity of the Adjuvanted Trivalent Subunit Influenza Vaccine and the Non-Adjuvanted Trivalent Subunit Influenza Vaccine Compared to the Non-Adjuvanted Trivalent Split
ClinicalTrials.gov study NCT01346592. IPD Sharing: Not stated. Countries: 5. Publications: 1.
A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD
ClinicalTrials.gov study NCT03734237. IPD Sharing: NO. Countries: 1. Publications: 9.
Clinical Study in Children, 6 Months to 3 Years of Age, to Assess Two Dose Levels of an Experimental Flu Vaccine, Using a Licensed Influenza Virus Vaccine, Vaxigrip® as the Control
ClinicalTrials.gov study NCT00778895. IPD Sharing: YES. Countries: 1. Publications: 1.
Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine
ClinicalTrials.gov study NCT03287830. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza
ClinicalTrials.gov study NCT00958776. IPD Sharing: Not stated. Countries: 23. Publications: 1.
Study of the Safety and Immunogenicity of an Influenza Vaccine Administered to Healthy Adults
ClinicalTrials.gov study NCT00264576. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.