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390
datasets available to search
ShareScore release 0.9.0
Dataset results
390 results for “mammary gland”
Cow mammary gland miRNomes before and after food restriction
GEO Series GSE146762. Bos taurus. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The RhoA guanine nucleotide exchange factor Net1 is required for PyMT mediated mammary gland tumorigenesis and metastasis
GEO Series GSE99643. Mus musculus. 6 samples. Type: Expression profiling by array.
Gene expression profiles of the mammary gland tumors from Nr1d1+/+;PyMT and Nr1d1-/-;PyMT mice
GEO Series GSE222645. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Perimenopausal and menopausal mammary glands in a 4-vinylcyclohexene diepoxide mouse model
<p><span>As both perimenopausal and menopausal periods are recognized critical windows of susceptibility for breast carcinogenesis, development of a physiologically relevant model has been warranted. The traditional ovariectomy model causes instant removal of the entire hormonal repertoire produced by the ovary, which does not accurately approximate human natural menopause with gradual transition. Here, we characterized the mammary glands of 4-vinylcyclohexene diepoxide (VCD)-treated animals at different time points, revealing that the model can provide the mammary glands with both perimenopausal and menopausal states. The perimenopausal gland showed moderate regression in ductal structure with no responsiveness to external hormones, while the menopausal gland showed severe regression with hypersensitivity to hormones. Leveraging the findings on the VCD model, effects of a major endocrine disruptor (polybrominated diphenyl ethers, PBDEs) on the mammary gland were examined during and after menopausal transition, with the two exposure modes; low-dose, chronic (environmental) and high-dose, subacute (experimental). All conditions of PBDE exposure did not augment or compromise the macroscopic ductal reorganization resulting from menopausal transition and/or hormonal treatments. Single-cell RNA sequencing revealed that the experimental PBDE exposure during the post-menopausal period caused specific transcriptomic changes in the non-epithelial compartment such as <em>Errfi1</em> upregulation in fibroblasts. The environmental PBDE exposure resulted in similar transcriptomic changes to a lesser extent. In summary, the VCD mouse model provides both perimenopausal and menopausal windows of susceptibility for the breast cancer research community. PBDEs, including all tested models, may affect the post-menopausal gland including impacts on the non-epithelial compartments.</span></p>
Study Into Treatment of Hyperplasia of Mammary Glands
ClinicalTrials.gov study NCT02505256. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy and Safety of Xiangjurupining Capsule for Hyperplasia of Mammary Glands
ClinicalTrials.gov study NCT06685978. IPD Sharing: NO. Countries: 1. Publications: 0.
A Clinical Study on the Efficacy and Safety of the Treatment of Hyperplasia of Mammary Glands With Xiaoru Sanjie Capsule
ClinicalTrials.gov study NCT02929420. IPD Sharing: YES. Countries: 1. Publications: 0.
Seroma of the Mammary Gland
ClinicalTrials.gov study NCT05899387. IPD Sharing: NO. Countries: 1. Publications: 0.
Study Evaluating the Utility of 18F-FDG PET in Assessing Early Response to Neoadjuvant Chemotherapy in Patients With Mammary Gland Cancer
ClinicalTrials.gov study NCT02386709. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pregnancy-activated fibroblasts of the mouse mammary gland
GEO Series GSE167438. Mus musculus. 6 samples. Type: Expression profiling by array.
Resident macrophages promote homeostasis of hyaluronan-associated extracellular matrix in the mammary gland stroma
GEO Series GSE148207. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Estrogen Receptor alpha ChIP-Seq in mouse mammary gland
GEO Series GSE43415. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CXCL12-CXCR4 signaling mediates the formation of a macrophageal niche for mammary gland development and tumorigenesis
GEO Series GSE275908. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Changing dynamics of the fibroblast differentiation hierarchy during mammary gland morphogenesis and tumorigenesis [scRNA-Seq I]
GEO Series GSE277228. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of luminal and basal cell subpopulations in the lactating versus pregnant mammary gland
GEO Series GSE60450. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNA-seq of 444 epithelial cells from the mammary glands of pubescent and adult mice
GEO Series GSE95445. Mus musculus. 444 samples. Type: Expression profiling by high throughput sequencing.
TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity [01a_bulk_rna_seq_PCX_Cre_shTRPS1]
GEO Series GSE243504. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Embryonic lethality and defective mammary gland development in activator function impaired conditional knock-in ErbB3V943R mice
GEO Series GSE146437. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNA-seq of 186 basal and luminal epithelial cells from the mammary gland of adult mice
GEO Series GSE95432. Mus musculus. 186 samples. Type: Expression profiling by high throughput sequencing.
Dll1-mediated crosstalk between mammary gland stem cells and their macrophageal niche
GEO Series GSE77504. Mus musculus. 6 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.