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1,923
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ShareScore release 0.9.0
Dataset results
1,923 results for “compounds”
Effect of a noval UHRF1-Targeted compound H93 on gene expression of DU145 prostate cancer cells.
GEO Series GSE222831. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
The gene expression change of MDA-MB-231 treated with HDAC/G4 dual-targeting compound
GEO Series GSE188629. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
PC3T: a signature-driven predictor of chemical compounds for cellular transition
GEO Series GSE231967. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Analysis of global transcriptional response of Mycobacterium tuberculosis H37Rv to the natural compound ethyl p-methoxycinnamate
GEO Series GSE41582. Mycobacterium tuberculosis H37Rv. 6 samples. Type: Expression profiling by array.
Transcriptomic Profiling Reveals Thyroid Hormone-Mediated and Compound-Specific Effects of Methimazole and Amitrole on Testis Development
GEO Series GSE315532. Rattus norvegicus. 83 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics-based Screening and Novel compound for Hepatocellular Carcinoma
GEO Series GSE291833. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Genomic and phenotypic alterations of the neuronal-like cells derived from the human embryonal carcinoma stem cells (NT2) caused by exposure to the organophosphorus compounds paraoxon and mipafox
GEO Series GSE38050. Homo sapiens. 9 samples. Type: Expression profiling by array.
Transcriptome analysis of high potent DCs using small molecule compounds
GEO Series GSE239334. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Characterize compounds that affect V(D)J recombination and chromsomal translocation using MP-HTGTS
GEO Series GSE242857. Mus musculus. 980 samples. Type: Other.
Hazard Assessment of High-Nitrogen Compounds: Coupling Transcriptomics with Multi-Cellular Co-Culture Assays Provides Accurate Systemic Toxicity Screening
GEO Series GSE90619. Homo sapiens. 47 samples. Type: Expression profiling by array.
A single cell-based computational platform to identify chemical compounds targeting desired sets of transcription factors for cellular conversion [Single-cell RNA-seq]
GEO Series GSE162909. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Uncommon single and compound EGFR mutations: clinical outcomes of a heterogeneous subgroup of NSCLC "
<p>This record contains raw data related to article “Uncommon single and compound EGFR mutations: clinical outcomes of a heterogeneous subgroup of NSCLC"</p> <p>Molecular characterization of non-small-cell lung cancer (NSCLC) is essential to define the correct therapeutic algorithm in metastatic disease. Approximately 90% of epidermal growth factor receptor (EGFR) mutations are usually associated with sensitivity to EGFR tyrosine kinase inhibitors (TKIs). The remaining 10% defines a small, extremely heterogeneous subgroup of mutations, with a varied profile of sensitivity and response to target therapies.This retrospective observational study includes 47 patients affected by metastatic NSCLC harboring uncommon EGFR mutations (single or compound mutation). Patients were treated with EGFR-targeting TKIs or platinum-based chemotherapy as first-line treatment.Median OS resulted longer in the compound mutation group when compared to single rare mutations (33.6 vs 12 months; P = 0.473); a similar result was observed for PFS (16 vs 7.6 months; P = 0.281), although statistical significance was not reached. ORR, PFS and OS resulted similar for patients treated with first-line EGFR TKIs or chemotherapy. No difference in terms of PFS and OS was found according to the TKI administered.Compound mutations seem to be a good prognostic indicator for OS; they are also predictive of response to 1st and 2nd generation EGFR TKIs, as well as exon 19 insertions and mutations in codon 719 of exon 18. For mutations in exon 18 (not in codon 719) and exon 20 insertions, chemotherapy seems the most effective available option. The addition of immunotherapy to chemotherapy could change this approach in the next future.</p>
Compounds NMR and conformational space data for tetrahydropyridine (12)
<p>- Compounds NMR data (FID).</p> <p>- .sdf files containing the whole conformers of cis- and trans-tetrahydropyridine (12) generated by the GMMX module on Gaussian 16. This conformational space was subjected to an ML-<em>J</em>-DP4 study as part of our work related to haouamine alkaloids.</p>
Understanding the deformation creep and role of intermetallic compound-microstructure in Sn-Ag-Cu solders
Open the record for dataset details and reuse information.
dataset related to article: "Spastic paraplegia type 46: novel and recurrent GBA2 gene variants in a compound heterozygous Italian patient with spastic ataxia phenotype"
<p>Dataset contains Genetic data in VCF format of an Italian patient with spastic ataxia phenotype</p>
Fig. 4. X in Diverse undescribed compounds from the rhizome of Zingiber officinale Rosc. And their anti-inflammatory activity
Fig. 4. X-ray crystallographic analysis of 2.
Fig. 1. Structures for compounds 1–13 in Bridged cassane derivatives from the seeds of Caesalpinia sappan L. and their cytotoxic activities
Fig. 1. Structures for compounds 1–13.
Fig. 4. Experimental and calculated ECD spectra for compound 1 in Jellynolide A, pokepola esters, and sponalisolides from the aquaculture sponge Spongia officinalis L
Fig. 4. Experimental and calculated ECD spectra for compound 1 in MeOH.
Fig. 2. Key HMBC and COSY correlations for compounds 1–4 in Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144)
Fig. 2. Key HMBC and COSY correlations for compounds 1–4.
Fig. 1 in Specialized compounds across ontogeny in the seagrass Posidonia oceanica
Fig. 1. Chemical structures of the five compounds (1–5) detected in Posidonia oceanica.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.