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5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
Expansion of in vivo HDAd-transduced HSPCs by constitutive expression of tHMGA2 without additional treatment allows for therapeutically relevant transgene expression in HSPC progeny cells without clon
GEO Series GSE268678. Mus musculus. 18 samples. Type: Other.
Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
GEO Series GSE168800. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing; Other.
A comparative miRNA/mRNA analysis in distinct murine liver cancer models reveals miR-193a-5p and NUSAP1 as therapeutic targets in HCC [miRNA]
GEO Series GSE102417. Mus musculus; Rattus norvegicus. 34 samples. Type: Expression profiling by RT-PCR.
The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells [RNA-seq]
GEO Series GSE193258. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
DNA demethylating agents represent a therapeutic opportunity for synovial sarcoma [RNA-Seq 2]
GEO Series GSE291312. Homo sapiens; Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Multi-omic analysis identifies metabolic biomarkers for early detection of breast cancer and prediction of therapeutic responses
GEO Series GSE268662. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Splicing of erythroid transcription factor is associated with therapeutic response in myelodysplastic syndromes [ChIP-Seq]
GEO Series GSE292213. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Therapeutic manipulation of SRSF1 mitigates genome-wide transcriptome alterations and neuronal hyperexcitability in C9ORF72-linked amyotrophic lateral sclerosis
GEO Series GSE139900. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapeutic approach for cardiac disease
GEO Series GSE210494. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Drug screening identifies tazarotene and bexarotene as therapeutic agents in Multiple Sulfatase Deficiency
GEO Series GSE205555. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing.
Antagonizing miR-128 abrogates chemoresistance-associated metastasis and is therapeutic in non-small cell lung cancer [miRNA]
GEO Series GSE67727. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by array.
Therapeutic modulation of NKG7 in CD8+ T cells increases anti-tumor cytotoxicity and improves response to immune checkpoint inhibitors
GEO Series GSE164237. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing; Other.
Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets [Bisulfite-Seq]
GEO Series GSE147343. Mus musculus. 49 samples. Type: Methylation profiling by high throughput sequencing.
RNA decay defines the therapeutic response to transcriptional perturbation in leukemia [TotalRNAseq K562 MYC clones]
GEO Series GSE229308. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets
GEO Series GSE174443. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Multi-omics Dissection of MAPK-driven Senescence Unveils Therapeutic Vulnerabilities in KIAA1549::BRAF-fusion Pediatric Low-Grade Glioma Models
GEO Series GSE287599. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Generation of a biliary tract cancer cell line atlas identifies molecular subtypes and therapeutic targets
GEO Series GSE295371. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Characterization of the menin-MLL interaction as therapeutic cancer target in solid tumor models
GEO Series GSE136272. Homo sapiens. 86 samples. Type: Expression profiling by high throughput sequencing.
Mutated fibroblast growth factor receptor 1 is an oncogenic driver and therapeutic target in high-risk neuroblastoma
GEO Series GSE313168. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Human single nuclear RNA sequencing identifies CD47 as a therapeutic target for doxorubicin-induced cardiomyopathy
GEO Series GSE292067. Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.