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2,012
datasets available to search
ShareScore release 0.9.0
Dataset results
2,012 results for “Kinase”
Triple kinase target modulation in an animal model of Alzheimer disease
GEO Series GSE227292. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Novel epoxy-tiglianes stimulate keratinocyte wound healing responses and re-epithelialization via protein kinase C activation
GEO Series GSE122297. Homo sapiens. 48 samples. Type: Expression profiling by array.
Influence of deficiency in mevalonate kinase (MVK) on wide gene expression in Saccharomyces cerevisiae
GEO Series GSE98163. Saccharomyces cerevisiae. 4 samples. Type: Expression profiling by array.
The Rio1 kinase downregulates RNA polymerase I to promote rDNA stability and segregation
GEO Series GSE54930. Saccharomyces cerevisiae. 6 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Complete atrio-ventricular canal defects in mouse hearts lacking G-protein receptor kinases
GEO Series GSE87321. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
The ErbB3 receptor tyrosine kinase regulates small intestinal barrier function and expression of the tight junctional protein Pmp22
GEO Series GSE308942. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Functional genomics-assisted identification of the Ypel5 gene as a novel negative regulator of the TBK1/IKBKE kinases and interferon-beta
GEO Series GSE81150. Mus musculus. 8 samples. Type: Expression profiling by array.
Dataset related to article "Survival outcome of tyrosine kinase inhibitors beyond progression in association to radiotherapy in oligoprogressive EGFR-mutant non-small-cell lung cancer."
<p><strong>Aim:</strong> The association of tyrosine kinase inhibitors (TKIs) and local radiotherapy in <em>EGFR</em>-mutated non-small-cell lung cancer patients experiencing disease progression under TKIs could be a valid an option. <strong>Patients & methods:</strong> We included 131 patients experiencing disease progression during first-line TKI. In group A, patients received TKI beyond progression and site(s) of progression were irradiated; in group B, patients remained on TKI alone beyond progression; and group C stopped TKI at first disease progression. <strong>Results:</strong> Median overall survival resulted longer in group A versus B and C (p < 0.0001). Group A had a trend toward a longer second progression-free survival (measured from the time of first progression until second progression) versus group B (p = 0.06). <strong>Conclusion:</strong> TKI beyond progression in association with local ablative treatment is a valid treatment option in oligoprogressive patients.</p> <p> </p> <p> </p>
Zalutumumab in Non-Small Cell Lung Cancer (NSCLC) Patients Refractory to Tyrosine Kinase Inhibitors
ClinicalTrials.gov study NCT01449357. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours
ClinicalTrials.gov study NCT01194193. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Identification of a novel TINCR-EGFR signaling pathway loop which initiates receptor tyrosine kinases cascade and confers tumorigenesis in human cancer [mRNA]
GEO Series GSE125330. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Systems biology of S.aureus adaptation under Ser/Thr kinase wild type and mutations of kinase (pknB) or phosphatase (stp)
GEO Series GSE122362. Staphylococcus aureus; Staphylococcus aureus subsp. aureus str. Newman. 12 samples. Type: Expression profiling by array.
Transcriptomic Analysis Identifies B-Lymphocyte Kinase as a Therapeutic Target for Desmoplastic Small Round Cell Tumor Cancer Stem Cell-Like Cells [RNA-seq]
GEO Series GSE248761. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
NSD2 Overexpression in Myeloma Enhances Dependency on Mitochondrial High Energy Phosphate Transport Facilitated by Adenylate Kinase 2 [AS_CR]
GEO Series GSE245148. Homo sapiens. 8 samples. Type: Other.
CD8+ T cell-1 dependent antitumor response boosted by dual blockade of PD-1 and VGFR2 following EGFR-tyrosine kinase inhibitors against lung cancer with Egfr mutation
GEO Series GSE197260. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
The sensor kinase QseC regulates the unlinked PmrA response regulator and downstream gene expression in Francisella
GEO Series GSE154698. Francisella tularensis subsp. novicida; Francisella tularensis. 16 samples. Type: Expression profiling by high throughput sequencing.
Differential expression analysis connects knock-downs of eIF3e and eIF3d with the MAP kinase signaling pathway
GEO Series GSE216967. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Other.
Methotrexate affects brain development by regulating serum-glucocorticoid inducible protein kinase 3 (SGK3) signal pathway in brain organoids.
GEO Series GSE262517. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Polo like kinase 2 (PLK2) promotes microglial activation via regulation of the HSP90α/IKKβ pathway
GEO Series GSE272635. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Protein kinase inhibitor-mediated immunoprophylactic and immunotherapeutic control of colon cancer
GEO Series GSE197598. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.