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2,009 results for “Disruption”

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geo12/100

Hexavalent chromium disrupts chromatin organization and accessibility to CTCF sites in promoters of differentially expressed genes [MNase-Seq]

GEO Series GSE104565. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2018View details →
geo12/100

Co-targeting EZH2 and TEAD elicits apoptosis through tumor-intrinsic innate immune signaling in Hippo pathway-mutated cancers - RNA-seq data from genetic disruption of EZH2

GEO Series GSE301957. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo12/100

Targeting FOXA1 and FOXA2 Disrupts the Lineage-Specific Oncogenic Output in Prostate Cancer

GEO Series GSE281794. Homo sapiens. 97 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo12/100

Viruses hijack FPN1 to disrupt iron withholding and suppress host defense

GEO Series GSE280144. Mus. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo12/100

Senescence leads to epigenomic disruption invoking hallmarks of reprogramming and pluripotency

GEO Series GSE53332. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenDec 2014View details →
geo12/100

The CTCF paralog CTCFL disrupts cohesin at active promoters. [human]

GEO Series GSE67094. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenAug 2025View details →
geo12/100

Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice

GEO Series GSE239339. Mus musculus. 47 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenJul 2023View details →
geo12/100

Oncogenic fatty acid oxidation senses sleep deficiency-induced circadian disruption to promote tumorigenesis [circadian]

GEO Series GSE216729. Mus musculus. 42 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo12/100

Disruption of Estrogen Signaling Enhances Invasiveness of Breast Cancer Cells by Attenuating a HER2-independent Gene Repression Program

GEO Series GSE53734. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenNov 2016View details →
geo12/100

Integrated Transcriptomic and Metabolomic Analyses for Circadian Disruption biomarker identification

GEO Series GSE299370. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo12/100

Chronic stress disrupts hepatic kynurenine pathway to subvert hepatic CD8+ T cell immunity and promote liver cancer

GEO Series GSE305657. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo12/100

Per- and polyfluoroalkyl substances (PFAS) suppress macrophage alternative activation to disrupt hepatic lipid metabolism [RNA-seq II]

GEO Series GSE284229. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo12/100

K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ)

GEO Series GSE232351. Saccharomyces cerevisiae. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo12/100

Developmental Exposure to Endocrine-Disrupting Chemicals Alters Gene Expression in Myometrium of Exposed Animals

GEO Series GSE106655. Rattus norvegicus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →
geo12/100

5-HT Reuptake Blockade Disrupts Genomic Stability-Based proteostasis to Induce Pyroptosis via Remodeling Histone Serotonylation [ChIP-seq]

GEO Series GSE282619. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo12/100

The histone H3G34R mutation disrupts the epigenome via catalytic inactivation of the ASH1 H3K36 methyltransferase [RNA-seq]

GEO Series GSE134451. Neurospora crassa. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2022View details →
geo12/100

Elimination of dormant cancer stem cells by disrupting glucocorticoid mediated lipid metabolism in glioblastoma

GEO Series GSE215245. Homo sapiens; Mus musculus. 59 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo12/100

KMT2D loss disrupts cell cycle and hypoxic responses in neurodevelopmental models of Kabuki syndrome

GEO Series GSE126167. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2019View details →
geo12/100

Lymphatic Disruption as a Driver of Lung Transplant Fibrosis

GEO Series GSE306618. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo12/100

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma [HSH3_ChIP-seq_HS-SY-II]

GEO Series GSE266199. Homo sapiens. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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