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1,943 results for “pulmonary disease”
Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy
GEO Series GSE236438. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary disease
GEO Series GSE307921. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Siglec-1−/FSClow alveolar macrophages exhibit pro-inflammatory phenotypes in chronic obstructive pulmonary disease
GEO Series GSE199345. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Disease-associated changes in the lung microbiome in patients with early chronic obstructive pulmonary disease
GEO Series GSE290402. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Single cells RNA sequencing of peripheral blood mononuclear cells reveals that hyperinflammatory monocytes are associated with Mycobaterium abscessus pulmonary disease
GEO Series GSE234785. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Identification and Bioinformatic Analysis of CircRNAs in the Plasma of Patients with Very Severe Chronic Obstructive Pulmonary Disease
GEO Series GSE221812. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease
GEO Series GSE197463. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
plasma circRNA-expression profiles in children with pulmonary hypertension secondary to congenital heart disease
GEO Series GSE171827. Homo sapiens. 13 samples. Type: Non-coding RNA profiling by array.
Lung miRNA expression profiling in a mouse model of chronic obstructive pulmonary disease
GEO Series GSE186955. Mus musculus. 31 samples. Type: Non-coding RNA profiling by array.
Dataset related to: "Effectiveness of pulmonary rehabilitation in individuals with Chronic Obstructive Pulmonary Disease according to inhaled therapy: The Maugeri study"
<p>We provide the raw data used for the following article:</p> <p>Vitacca M, Paneroni M, Spanevello A, Ceriana P, Balbi B, Salvi B, Ambrosino N. <strong>Effectiveness of pulmonary rehabilitation in individuals with Chronic Obstructive Pulmonary Disease according to inhaled therapy: The Maugeri study.</strong> Respir Med. 2022 Oct;202:106967. doi: 10.1016/j.rmed.2022.106967. </p> <p>ABSTRACT</p> <p>Background and aim: Real-life studies report discordant prescribing of inhaled triple therapy (TT) among individuals<br> with COPD. Guidelines recommend pulmonary rehabilitation (PR) for persistent breathlessness and/or<br> exercise limitation. This real-life study aimed to assess the effects of in-patient PR in individuals under TT as<br> compared to other inhaled therapies (no TT).<br> Methods: Multicentric, retrospective analysis of data from individuals admitted to in-hospital PR. Baseline<br> characteristics were recorded and lung function was assessed. Outcome measures were: 6-min walking test<br> (6MWT: primary outcome), Medical Research Council (MRC) scale for dyspnoea, and COPD assessment test<br> (CAT).<br> Results: Data of pre and post program 6MWT of 1139 individuals were available. Pulmonary rehabilitation<br> resulted in significant improvement in 6MWT in both groups, however, the effect size (by 54.3 ± 69.7 vs 42.5 ±<br> 64.2 m, p = 0.004) and proportion of individuals reaching the minimal clinically important difference (MCID) of<br> 6MWT (64.2%, vs 54.3%, p = 0.001) were higher in TT group. Both groups significantly improved also the other<br> outcome measures. The significant independent predictors of reaching the MCID of 6MWT were hospital provenience,<br> TT use, and high eosinophils count.<br> Conclusion: Pulmonary rehabilitation results in significant benefits in individuals with COPD irrespective of the<br> use of TT. However, individuals under TT report larger benefits in exercise tolerance than those under no TT.</p>
Inhaled Treprostinil Expanded Access Program in Pulmonary Hypertension Associated With Interstitial Lung Disease
ClinicalTrials.gov study NCT05572996. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Immunological characteristics of non-tuberculous mycobacterial pulmonary disease
GEO Series GSE290289. Homo sapiens. 24 samples. Type: Expression profiling by array.
A preliminary study on the screening and mechanism of miRNA as a biomarker for patients with different progressive chronic obstructive pulmonary disease (COPD)
GEO Series GSE220441. Homo sapiens. 19 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Delineating the angiogenic gene expression profile prior to pulmonary vascular remodeling in a lamb model of congenital heart disease
GEO Series GSE22590. Bos taurus; Ovis aries. 16 samples. Type: Expression profiling by array.
The site and nature of terminal bronchiolar destruction in chronic obstructive pulmonary disease (COPD).
GEO Series GSE151052. Homo sapiens. 117 samples. Type: Expression profiling by array.
Gene expression in chronic obstructive pulmonary disease (COPD) patients
GEO Series GSE77344. Homo sapiens. 172 samples. Type: Expression profiling by array.
Association of sputum microbiome with exacerbations, patient subgroups and host response in chronic obstructive pulmonary disease
GEO Series GSE112165. Homo sapiens. 41 samples. Type: Expression profiling by array.
Chronic obstructive pulmonary disease
GEO Series GSE475. Homo sapiens. 7 samples. Type: Expression profiling by array.
Chest X-ray images dataset of viral and bacterial pulmonary diseases.
Open the record for dataset details and reuse information.
Pulmonary thromboembolism in coronavirus disease 2019 patients undergoing thromboprophylaxis
<p>Dataset from Schiaffino S, Giacomazzi F, Esseridou A, Cozzi A, Carriero S, Mazzaccaro DP, Nano G, Di Leo G, Spagnolo P, Sardanelli F. Pulmonary thromboembolism in coronavirus disease 2019 patients undergoing thromboprophylaxis. Medicine (Baltimore). 2021 Jan 8;100(1):e24002. doi: 10.1097/MD.0000000000024002. PMID: 33429763; PMCID: PMC7793450.</p> <p>Abstract</p> <p>We aimed to investigate the prevalence of pulmonary thromboembolism (PTE) and its association with clinical variables in a cohort of hospitalized coronavirus disease 2019 (COVID-19) patients receiving low-molecular-weight heparin (LMWH) at prophylactic dosage.In this retrospective observational study we included COVID-19 patients receiving prophylactic LMWH from admission but still referred for lower-limbs venous Doppler ultrasound (LL-US) and computed tomography pulmonary angiography (CTPA) for clinical PTE suspicion. A dedicated radiologist reviewed CTPA images to assess PTE presence/extension.From March 1 to April 30, 2020, 45 patients were included (34 men, median age 67 years, interquartile range [IQR] 60-76). Twenty-seven (60%) had PTE signs at CTPA, 17/27 (63%) with bilateral involvement, none with main branch PTE. In 33/45 patients (73%) patients LL-US was performed before CTPA, with 3 patients having superficial vein thrombosis (9%, none with CTPA-confirmed PTE) and 1 patient having deep vein thrombosis (3%, with CTPA-confirmed PTE). Thirty-three patients (73%) had at least one comorbidity, mainly hypertension (23/45, 51%) and cardiovascular disease (15/45, 33%). Before CTPA, 5 patients had high D-dimer (11.21 μg/mL, IQR 9.10-13.02), 19 high fibrinogen (550 mg/dL, IQR 476-590), 26 high interleukin-6 (79 pg/mL, IQR 31-282), and 11 high C-reactive protein (9.60 mg/dL, IQR 6.75-10.65), C-reactive protein being the only laboratory parameter significantly differing between patients with and without PTE (P = .002)High PTE incidence (60%) in COVID-19 hospitalized patients under prophylactic LMWH could substantiate further tailoring of anticoagulation therapy.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.