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316
datasets available to search
ShareScore release 0.9.0
Dataset results
316 results for “β-catenin”
Inhibition of SCFKDM2A/USP22-dependent nuclear β-catenin ubiquitylation mediates cerebral ischemic tolerance
Open the record for dataset details and reuse information.
Figure S1: β-catenin expression is controls and T-ALL patients.
<p>β-catenin expression is controls and T-ALL patients.</p>
Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway.
ClinicalTrials.gov study NCT02077777. IPD Sharing: NO. Countries: 1. Publications: 7.
Study on the Probiotics Regulating miRNA in H. Pylori-induced Wnt/β-catenin Gastric Carcinogenesis.
ClinicalTrials.gov study NCT05544396. IPD Sharing: NO. Countries: 1. Publications: 3.
Data from: Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
Signaling filopodia, termed cytonemes, are dynamic actin-based membrane structures that regulate the exchange of signaling molecules and their receptors within tissues. However, how cytoneme formation is regulated remains unclear. Here, we show that Wnt/PCP autocrine signaling controls the emergence of cytonemes, and that cytonemes subsequently control paracrine Wnt/β-catenin signal activation. Upon binding of the Wnt family member Wnt8a, the receptor tyrosine kinase Ror2 gets activated. Ror2/PCP signaling leads to induction of cytonemes, which mediate transport of Wnt8a to neighboring cells. In the Wnt receiving cells, Wnt8a on cytonemes triggers Wnt/β-catenin-dependent gene transcription and proliferation. We show that cytoneme-based Wnt transport operates in diverse processes, including zebrafish development, the murine intestinal crypt, and human cancer organoids, demonstrating that Wnt transport by cytonemes and its control via the Ror2 pathway is highly conserved in vertebrates.
Data from: Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
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Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation
GEO Series GSE41892. Homo sapiens. 4 samples. Type: Expression profiling by array.
Diverse Targets of β-catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
GEO Series GSE67571. Homo sapiens. 4 samples. Type: Expression profiling by array.
Excessive β-catenin in excitatory neurons results in reduced social and increased repetitive behaviors and altered expression of multiple genes linked to human autism
GEO Series GSE147034. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Metabolic programs orchestrated by the activated Ha-ras and β-catenin oncoproteins in mouse liver tumors
GEO Series GSE51358. Mus musculus. 48 samples. Type: Expression profiling by array; Non-coding RNA profiling by array; Protein profiling by protein array.
WNT3 Promotes Chemoresistance in Oral Squamous Cell Carcinoma via Activating the Canonical β-catenin Pathway
GEO Series GSE248792. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of Wnt knockdown embryos reveals candidate canonical Wnt/β-catenin target genes during Xenopus laevis gastrulation
GEO Series GSE77364. Xenopus laevis. 6 samples. Type: Expression profiling by high throughput sequencing.
The loss of an orphan nuclear receptor NR2E3 augments Wnt/β-Catenin signaling via epigenetic dysregulation that promotes the Sp1-β catenin-p300 interactions in hepatocellular carcinoma.
GEO Series GSE243020. Mus musculus; Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Brain pericytes and Wnt/β-catenin signaling induce functional blood-brain barrier phenotype in human iPSC-derived model
GEO Series GSE305015. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer.
GEO Series GSE226589. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Gene expression profiling of HepG2 cells after knockdown of β-catenin
GEO Series GSE94858. Homo sapiens. 6 samples. Type: Expression profiling by array.
Endocrine disruption of early uterine differentiation causes adenocarcinoma mediated by Wnt/β-catenin- and PI3K/AKT signaling
GEO Series GSE218156. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Eurycomalactone switches hepatocellular carcinoma cells into a quiescence state through 5'tRFAla&5'tiRNAAla/DVL/β-catenin pathway inhibition
GEO Series GSE236560. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by array.
Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin–mediated prostatic tumorigenesis
GEO Series GSE142158. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Identifying microRNAs targeting WNT/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertension
GEO Series GSE67597. Homo sapiens. 15 samples. Type: Non-coding RNA profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.