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73 results for “• Ischaemic stroke”
Quantification of stroke lesion volume using epidural EEG in a cerebral ischaemic rat model
<p>We have uploaded the dataset of rat EEG in response to the specific sound stimuli. The dataset includes rat EEG of normal subjects (n = 10), mild (n = 7), moderate (n = 7), and severe (n = 7) right auditory cortical infarction subjects. </p> <p>The dataset can be analyzed using MATLAB software. For power spectrum density (PSD) analysis of the data, we used the zero-phase forward and reverse Infinite Impulse Response Butterworth filter of 4th order. Further, we averaged the last 300 ms of the signal before stimulus onset as a baseline correction. Next, we down-sampled the data from 1,200 to 600 Hz. Subsequently, we conducted the PSD analysis using signals obtained from the target stimulus onset to 1 s using Welch’s method, which is one of the most widely used periodogram methods for determining the power density of EEG frequency components. The parameter was set to divide the EEG signals into eight sections of equal length, each with a 50% overlap based on the Hamming window. We defined the frequency range for each band as follows: Delta (1-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), and beta (12-30 Hz). We calculated the relative power for each frequency band by summing all of the absolute PSD values across the four bands to compute the total power followed by dividing the absolute value for each frequency band with the total power. Finally, we calculated the DAR (delta/alpha ratio) and the DTABR ((delta + theta) / (alpha + beta) ratio), which were computed by the relative power of the relevant frequency bands. Further, we analysed AEPs in response to the target sound stimuli by averaging all of the epochs between 300 ms before the stimuli onset to 500 ms after it. The AEP amplitude was defined as the highest recorded voltage following the sound stimulus. The latency of the components of the AEPs was defined as the duration from stimulus onset to the peak amplitude.</p>
Risk and predictors of stroke recurrence after ischaemic stroke: a prospective cohort study in a mountainous province of central highlands in Vietnam
<p>Dataset associated with "Risk and predictors of stroke recurrence after ischaemic stroke: a prospective cohort study in a mountainous province of central highlands in Vietnam" manuscript</p>
THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death
ClinicalTrials.gov study NCT03354429. IPD Sharing: Not stated. Countries: 28. Publications: 9.
Alteplase Treatment in Elderly Acute Ischaemic Stroke (AIS) Patients
ClinicalTrials.gov study NCT05401149. IPD Sharing: NO. Countries: 1. Publications: 1.
A Proof of Concept Study to Evaluate the Safety of Afamelanotide in Patients With Acute Arterial Ischaemic Stroke (AIS)
ClinicalTrials.gov study NCT04962503. IPD Sharing: Not stated. Countries: 1. Publications: 1.
1-year Clinical Outcomes in Recombinant Tissue Plasminogen Activator (Rt-PA) Treated Chinese Acute Ischaemic Stroke (AIS) Patients
ClinicalTrials.gov study NCT05395338. IPD Sharing: NO. Countries: 1. Publications: 0.
[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]
ClinicalTrials.gov study NCT01994720. IPD Sharing: Not stated. Countries: 33. Publications: 12.
Proof of Concept (POC) in Patients With Ischaemic Stroke
ClinicalTrials.gov study NCT01808261. IPD Sharing: YES. Countries: 4. Publications: 1.
Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.
ClinicalTrials.gov study NCT05417009. IPD Sharing: YES. Countries: 1. Publications: 2.
Spectrum of cerebral arteriopathies in children with arterial ischaemic stroke
<p><span><b>Objective: </b>To determine that children with arterial ischaemic stroke due to an identifiable arteriopathy are distinct from those without arteriopathy, and that each arteriopathy subtype has unique and recognizable clinical features.</span></p> <p><b>Methods: </b>We report a large, observational, multicenter cohort of children with AIS, age 1-month to 18-years, enrolled into the International Pediatric Stroke Study from 2003 to 2014. Clinical and demographic differences were compared using the Fisher exact test, with linear step-up permutation min-<i>p</i> adjustment for multiple comparisons. Exploratory analyses were conducted to evaluate differences between AIS cases with and without arteriopathy and between arteriopathy subtypes.</p> <p><b>Results: </b>Of 2,127 children with AIS, 725 (34%) had arteriopathy (median age 7.45 years). Arteriopathy subtypes included: dissection (27%), moyamoya (24.5%), focal cerebral arteriopathy–inflammatory subtype (FCA-i, 15%), diffuse cerebral vasculitis (15%), and non-specific arteriopathy (18.5%). Children with arteriopathic AIS were more likely to present between 6-9 years of age (p=0.029, OR 1.93), with headache (p=0.023, OR 1.55), multiple infarctions (p<0.001, OR 2.05), sickle cell anemia (p=0.007, OR 2.9), and head/neck trauma (p=0.018, OR 1.93). Antithrombotic usage and stroke recurrence were higher in children with arteriopathy. Among arteriopathy subtypes, patient with dissection were associated with male sex, older age, headache, and anticoagulant use; FCA-i with hemiparesis and single infarcts; moyamoya with seizures and recurrent strokes; and vasculitis with bilateral infarctions.</p> <p><b>Conclusion: </b>Specific clinical profiles are associated with cerebral arteriopathies in children with AIS. These observations may be helpful indicators in guiding early diagnosis and defining subgroups that may benefit most from future therapeutic trials.</p>
Remote Ischaemic Conditioning After Stroke Trial (ReCAST-2)
ClinicalTrials.gov study NCT02779712. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ExStroke Pilot Trial: Physical Exercise After Acute Ischaemic Stroke
ClinicalTrials.gov study NCT00132483. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Cohort Study for Severe Ischaemic Stroke
ClinicalTrials.gov study NCT03222024. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Pragmatic Ischaemic Stroke Thrombectomy Evaluation
ClinicalTrials.gov study NCT01745692. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE
ClinicalTrials.gov study NCT05762146. IPD Sharing: NO. Countries: 1. Publications: 1.
OPTIMAS: OPtimal TIMing of Anticoagulation After Acute Ischaemic Stroke : a Randomised Controlled Trial
ClinicalTrials.gov study NCT03759938. IPD Sharing: NO. Countries: 1. Publications: 4.
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-bl
ClinicalTrials.gov study NCT03148457. IPD Sharing: NO. Countries: 15. Publications: 9.
Reduction of Prehospital Delays in Stroke and Transient Ischaemic Attack (TIA)
ClinicalTrials.gov study NCT00744029. IPD Sharing: Not stated. Countries: 1. Publications: 5.
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
ClinicalTrials.gov study NCT05636748. IPD Sharing: UNDECIDED. Countries: 1. Publications: 14.
rhPro-UK in Acute Ischaemic Stroke Within 4.5 Hours of Stroke Onset Trial 2(PROST-2)
ClinicalTrials.gov study NCT05700591. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.