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21 results for “4-triazole”

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dryad36/100

Data for: On-resin synthesis and late-stage functionalization of macrocyclic atosiban mimetics via 5-iodo-1,4-triazoles

Open the record for dataset details and reuse information.

publicSep 2025View details →
zenodo32/100

Experimental Data for Dynamic Flow Reactions of 1,2,4-Triazole with Acrylonitrile

<p>The reaction input flow rates, temperatures and concentrations are provided for time intervals of roughly 12 s. At each of these points,&nbsp;the concentration of four species was&nbsp;measured by online benchtop NMR analysis and these concentrations are provided.</p> <p>Experiments 1-7 and the self-optimization data are detailed in the manuscript (part 1).</p>

opencc-by-4.0Apr 2023View details →
zenodo28/100

Scheme 4 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 4 Synthesis of salts of 2-(4-)((4-phenyl-5-phenethyl-4H-1,2,4-triazole-3-yl)thio)ethanoic acids.

opencc-by-4.0Jan 2021View details →
zenodo28/100

Scheme 7 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 7 Synthesis of 6-((4-R-5-phenethyl-1,2,4-triazole-3-ylthio)pyridine-3-yl)-(alkyl-, heteryl)methanimines.

opencc-by-4.0Jan 2021View details →
zenodo28/100

Figure 1 from: Bak PG, Belenichev IF, Kucherenko LI, Abramov AV, Khromylоva OV (2021) Morpho-functional indicators changes of rats' myocardium in experimental doxorubicin-induced chronic heart failure and its  pharmacological modulation with new 4-amino-1,2,4-triazole derivative. Pharmacia 68(4): 919-925. https://doi.org/10.3897/pharmacia.68.e75298

Figure 1 Hypothetical mechanism of the compound "Hypertril" positive effect on the morpho-functional parameters of rat cardiomyocytes in experimental doxorubicin-induced CHF.

opencc-by-4.0Dec 2021View details →
zenodo28/100

Figure 5 from: Dovbnya DV, Kaplaushenko AH, Frolova YS, Pruglo ES (2022) Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles. Pharmacia 69(1): 135-142. https://doi.org/10.3897/pharmacia.69.e74107

Figure 5 Mass spectra of 2-((5-(2,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)acetonitrile (2.1).

opencc-by-4.0Feb 2022View details →
zenodo28/100

Figure 4 from: Dovbnya DV, Kaplaushenko AH, Frolova YS, Pruglo ES (2022) Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles. Pharmacia 69(1): 135-142. https://doi.org/10.3897/pharmacia.69.e74107

Figure 4 Mass spectra of 4-((5-(2,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)butanenitrile (2.3).

opencc-by-4.0Feb 2022View details →
zenodo28/100

Figure 2 from: Dovbnya DV, Kaplaushenko AH, Frolova YS, Pruglo ES (2022) Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles. Pharmacia 69(1): 135-142. https://doi.org/10.3897/pharmacia.69.e74107

Figure 2 Scheme of the synthesis of ((5-(2,4- and 3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)aceto(propanoic, benzoic)acids (compounds 2.12–2.14).

opencc-by-4.0Feb 2022View details →
zenodo28/100

Figure 1 from: Dovbnya DV, Kaplaushenko AH, Frolova YS, Pruglo ES (2022) Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles. Pharmacia 69(1): 135-142. https://doi.org/10.3897/pharmacia.69.e74107

Figure 1 Scheme of the synthesis of ((5-(2,4- and 3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)aceto(propano-, butano-, benzo)nitriles (compounds 2.1–2.11).

opencc-by-4.0Feb 2022View details →
zenodo28/100

Figure 3 from: Dovbnya DV, Kaplaushenko AH, Frolova YS, Pruglo ES (2022) Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles. Pharmacia 69(1): 135-142. https://doi.org/10.3897/pharmacia.69.e74107

Figure 3 IR spectra of 2-(((5-(3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)methyl)benzonitrile (2.9).

opencc-by-4.0Feb 2022View details →
zenodo28/100

Supplementary material 2 from: Alsaad H, Kubba A, Tahtamouni LH, Hamzah AH (2022) Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety. Pharmacia 69(2): 415-428. https://doi.org/10.3897/pharmacia.69.e83158

Figure S2

opencc-zeroMay 2022View details →
zenodo28/100

Supplementary material 1 from: Alsaad H, Kubba A, Tahtamouni LH, Hamzah AH (2022) Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety. Pharmacia 69(2): 415-428. https://doi.org/10.3897/pharmacia.69.e83158

Figure S1

opencc-zeroMay 2022View details →
zenodo28/100

Figure 2 from: Karpun Ye, Parchenko V, Fotina T, Demianenko D, Fotin A, Nahornyi V, Nahorna N (2021) The investigation of antimicrobial activity of some s-substituted bis-1,2,4-triazole-3-thiones. Pharmacia 68(4): 797-804. https://doi.org/10.3897/pharmacia.68.e65761

Figure 2 (A) Scheme of synthesizing the S-derivatives of bis-1,2,4-triazoles; (B) Scheme of synthesizing the S-amides of bis-1,2,4-triazoles.

opencc-by-4.0Oct 2021View details →
zenodo24/100

Scheme 3 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 3 Synthesis of 2-((4-R-5-phenethyl-4H-1,2,4-triazole-3-yl)thio)acetic(benzoic) acids.

opencc-by-4.0Jan 2021View details →
zenodo24/100

Scheme 2 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 2 Synthesis of 2-((4-R-5-phenethyl-4H-1,2,4-triazole-3-yl)thio)nitriles.

opencc-by-4.0Jan 2021View details →
zenodo24/100

Scheme 1 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 1 Synthesis of 4-R-5-phenethyl-4H-1,2,4-triazole-3-thiols.

opencc-by-4.0Jan 2021View details →
zenodo24/100

Scheme 5 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 5 Synthesis of alkyl 2-((4-ethyl-5-phenethyl-1,2,4-triazole-3-yl)thio)acet(benz)imidates.

opencc-by-4.0Jan 2021View details →
zenodo24/100

Scheme 6 from: Ihnatova T, Kaplaushenko A, Frolova Y, Pryhlo E (2021) Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles. Pharmacia 68(1): 129-133. https://doi.org/10.3897/pharmacia.68.e53320

Scheme 6 Synthesis of 3-(heptylthio)-5-phenethyl-4H-1,2,4-triazole.

opencc-by-4.0Jan 2021View details →
zenodo24/100

Figure 4 from: Karpun Ye, Parchenko V, Fotina T, Demianenko D, Fotin A, Nahornyi V, Nahorna N (2021) The investigation of antimicrobial activity of some s-substituted bis-1,2,4-triazole-3-thiones. Pharmacia 68(4): 797-804. https://doi.org/10.3897/pharmacia.68.e65761

Figure 4 Visualization of 3D structure of the "ligand-enzyme" complex.

opencc-by-4.0Oct 2021View details →
zenodo24/100

Figure 3 from: Karpun Ye, Parchenko V, Fotina T, Demianenko D, Fotin A, Nahornyi V, Nahorna N (2021) The investigation of antimicrobial activity of some s-substituted bis-1,2,4-triazole-3-thiones. Pharmacia 68(4): 797-804. https://doi.org/10.3897/pharmacia.68.e65761

Figure 3 Interaction network between the enzyme 4R4S and selected compounds.

opencc-by-4.0Oct 2021View details →

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