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3 results for “5α-dihydrotestosterone”
Data from: incubation as a driver of maternal effects: temperature influences levels of yolk maternally derived 5α-dihydrotestosterone
<p>In birds, maternal hormones deposited into eggs in response to environmental stimuli can impact offspring phenotype. Although less studied, environmental conditions can also influence females' incubation behavior, which might play a role in regulating embryo exposure to maternal hormones through changes in incubation temperature that affect the activity of the enzymes responsible for converting testosterone (T) to 5α-dihydrotestosterone (DHT) or estradiol. Here, we tested the hypothesis that the initial T content of the yolk and incubation temperature determine exposure to T metabolites during early embryo development. In the Japanese quail (<em>Coturnix japonica</em>), we experimentally manipulated yolk T and incubation temperature (38° C versus 36° C) and analyzed DHT and estradiol titers on day four of incubation. We found that eggs with experimentally increased T and those incubated at 36° C showed higher DHT concentration in egg yolk (with no synergistic effect of the two treatments). Estradiol titers were not affected by T manipulation or incubation temperature. Our study suggests that incubation temperature influences DHT titers and may act as an understudied source of maternal influence on offspring phenotype.</p>
Data from: incubation as a driver of maternal effects: temperature influences levels of yolk maternally derived 5α-dihydrotestosterone
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Effects of 5α-dihydrotestosterone on male mummichog (Fundulus heteroclitus) testes steroid production and gene expression patterns
GEO Series GSE48582. Fundulus heteroclitus. 8 samples. Type: Expression profiling by array.
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