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20 results for “ABC Transporter”
Data set for "On the interplay between lipids and asymmetric dynamics of an NBS degenerate ABC transporter"
<p>Supplementary data from molecular dynamics simulations performed on different states of bMRP1 (IF apo, IF ATP- and/or LTX-bound, as well as OF ATP-bound states) and embedded in different lipid bilayer membranes (namely POPC, POPE, POPC:POPE (3:1), POPC-Chol (3:1) and POPC:POPE:Chol (2:1:1).</p> <p>Are included:</p> <p>- Initial and postMD data</p> <p>- MD inputs used</p> <p>- Raw source data used for plot (ABC structural parameters, H-bond and non-covalent analyses, lipid order parameters, and efficiencies from Allopath tool)</p> <p>- PCA supplementary movies (PC1)</p>
Supplemental information and raw data: Developmental and caste-specific expression patterns of ATP-Binding Cassette (ABC) transporters in honey bees (Apis mellifera)
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Exploring the ligand binding and conformational dynamics of the substrate binding domain 1 of the ABC transporter GlnPQ
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Structural basis for lipid and copper regulation of the ABC transporter MsbA
<p>Raw native MS data for manuscript</p>
Transcriptional profiling of orf19.5100/MLT1 ABC transporter knockout in Candida albicans
GEO Series GSE70341. Candida albicans. 4 samples. Type: Expression profiling by array.
Expression and Splicing of ABC and SLC Transporters in the Blood-Brain Barrier
GEO Series GSE94064. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Elucidation of the substrate specificity of the ABC transporter Tba uncovers an unsuspected role in the biosynthesis of glycopeptide antibiotics
GEO Series GSE274067. Amycolatopsis balhimycina. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of the effect of kanamycin and the ABC transporter AtWBC19 on Arabidopsis thaliana seedlings reveals changes in metal content
GEO Series GSE58662. Arabidopsis thaliana. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling of putative ABC Transporter gene orf19.4531 knockout in Candida albicans
GEO Series GSE70340. Candida albicans. 4 samples. Type: Expression profiling by array.
Data from: Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey
Background: Lampreys are extant representatives of the jawless vertebrate lineage that diverged from jawed vertebrates around 500 million years ago. Lamprey genomes contain information crucial for understanding the evolution of gene families in vertebrates. The ATP-binding cassette (ABC) gene family is found from prokaryotes to eukaryotes. The recent availability of two lamprey draft genomes from sea lamprey Petromyzon marinus and Japanese lamprey Lethenteron japonicum presents an opportunity to infer early evolutionary events of ABC genes in vertebrates. Results: We conducted a genome-wide survey of the ABC gene family in two lamprey draft genomes. A total of 37 ABC transporters were identified and classified into seven subfamilies; namely seven ABCA genes, 10 ABCB genes, 10 ABCC genes, three ABCD genes, one ABCE gene, three ABCF genes, and three ABCG genes. The ABCA subfamily has expanded from three genes in sea squirts, seven and nine in lampreys and zebrafish, to 13 and 16 in human and mouse. Conversely, the multiple copies of ABCB1-, ABCG1-, and ABCG2-like genes found in sea squirts have contracted in the other species examined. ABCB2 and ABCB3 seem to be new additions in gnathostomes (not in sea squirts or lampreys), which coincides with the emergence of the gnathostome-specific adaptive immune system. All the genes in the ABCD, ABCE and ABCF subfamilies were conserved and had undergone limited duplication and loss events. In the sea lamprey transcriptomes, the ABCE and ABCF gene subfamilies were ubiquitously and highly expressed in all tissues while the members in other gene subfamilies were differentially expressed. Conclusions: Thirteen more lamprey ABC transporter genes were identified in this study compared with a previous study. By concatenating the same gene sequences from the two lampreys, more full length sequences were obtained, which significantly improved both the assignment of gene names and the phylogenetic trees compared with a previous analysis using partial sequences. The ABC gene subfamilies in chordates have undergone obvious expansion or contraction. The ABCA subfamily showed the highest gene expansion rate during chordate evolution. The evolution of ABC transporters in lampreys requires further evaluation because the present results are based on a draft genome.
The expression profile of ABC transporter genes in post-treatment breast carcinomas
GEO Series GSE43807. Homo sapiens. 111 samples. Type: Expression profiling by RT-PCR.
Stickleback embryos use ABC transporters as a buffer against exposure to maternally derived cortisol
GEO Series GSE71649. Gasterosteus aculeatus. 18 samples. Type: Expression profiling by high throughput sequencing.
Data from: Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey
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Side population phenotype in quiescent human/murine tissue resident memory (TRM) T cells: Role of ABC transporters and NR4A1 in TRM biology
GEO Series GSE85074. Homo sapiens. 7 samples. Type: Expression profiling by array.
abc transporters in Dictyostelium discoideum development
GEO Series GSE45555. Dictyostelium discoideum AX4. 282 samples. Type: Expression profiling by high throughput sequencing.
Regulation of ABC Transporters and Ergosterol Biosynthesis by the Transcription Factor FvADS-1 Controls Azole Resistance and Virulence in Fusarium verticillioides
GEO Series GSE315078. Fusarium verticillioides. 8 samples. Type: Expression profiling by high throughput sequencing.
Adaptation of Cupriavidus metallidurans CH34 to toxic zinc concentrations involves an uncharacterized ABC-type transporter
GEO Series GSE156826. Cupriavidus metallidurans CH34; Cupriavidus metallidurans. 3 samples. Type: Expression profiling by array.
CRISPRa screen identifies a role for c-KIT signaling in tamoxifen resistance, potentially through upregulation of ABC transporters
GEO Series GSE212111. Homo sapiens. 16 samples. Type: Other.
Transcriptional profiling of putative half ABC transporter gene orf19.3120 knockout cells in Candida albicans
GEO Series GSE70339. Candida albicans. 4 samples. Type: Expression profiling by array.
The Plasmodium falciparum protein PfMRP1 functions as an influx ABC transporter
GEO Series GSE195649. Plasmodium falciparum 3D7; Plasmodium falciparum Dd2. 4 samples. Type: Expression profiling by high throughput sequencing.
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