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3 results for “AC/A ratio”

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dryad32/100

Botulinum toxin in the treatment of partially accommodative esotropia with high AC/A ratio

<p class="MsoNormal"><a name="OLE_LINK3"></a><a name="OLE_LINK6"></a><a name="OLE_LINK5"><span><span><b><span>Purpose:</span></b></span></span></a><span><span><span><span> To study the outcome of botulinum toxin (BTX) treatment (group 1) in partially accommodative esotropia with high accommodative convergence/accommodation (AC/A) ratio, in comparison with bilateral medial rectus muscles recessions and posterior fixation (group 2).</span></span></span></span></p><p></p><p></p> <p class="MsoNormal"><span><span><span><b><span>Methods:</span></b></span></span></span><span><span><span><span> In a retrospective comparative study, children aged 3-8 years old treated between 2011 and 2016, with partially accommodative esotropia with high AC/A ratio, deviation at distance of 10 prism diopters or more, and at least 1 year of follow-up, were included. Visual acuity, alternate prism and cover test, stereoacuity, biomicroscopy, and cycloplegic retinoscopy were carried out at initial, baseline visit, 6 months and 1 year after BTX injection or surgery. Main outcome variables were deviation at distance and near, improvement in stereoacuity, and percentage of success. We used multiple regression or proportional odds analysis to control for potential confounding variables.</span></span></span></span></p><p></p><p></p> <p class="MsoNormal"><span><span><span><b><span>Results:</span></b></span></span></span><span><span><span><span> Of 95 patients, 84 were eligible, 48 children in group 1 and 36 in group 2. Deviation and stereoacuity were similar in the two groups at 6 months, but significantly better in the BTX group at 1 year (median distance deviation 0 prism diopters vs 5 prism diopters, p&lt;0.01), although differences were not clinically relevant. Percentage of success was also significantly better only at 1 year (93% vs 72%, p=0.01). Change in distance-near disparity was not significantly different in the two groups in the period of study.</span></span></span></span></p><p></p><p></p> <p></p> <p class="MsoNormal"><span><span><span><b><span>Conclusions:</span></b></span></span></span><span><span><span><span> Botulinum toxin could be superior to, or as effective as surgery, at middle term, in the treatment of partially accommodative esotropia with high AC/A ratio. </span></span></span></span><span><span></span></span></p><p></p><p></p>

opencc-zeroFeb 2020View details →
dryad32/100

Botulinum toxin in the treatment of partially accommodative esotropia with high AC/A ratio

Open the record for dataset details and reuse information.

publicFeb 2020View details →
ClinicalTrials.gov24/100

The Effect of Slanted Recession of Horizontal Muscle on Horizontal Strabismus With Abnormal Accommodative Convergence /Accommodation Ratio (AC/A)

ClinicalTrials.gov study NCT03555045. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →

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International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

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OpenNeuro

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Last verified 2026-04-29Open record