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5 results for “ARSR”
Association Rules and Semantic Relatedness (ARSR) - Evaluation Data
<p><em><strong>ARSR</strong></em> stands for "<strong><em>Association Rules and Semantic Relatedness</em></strong>",<br> a recommender system that combines association rule mining and semantic relatedness to create recommendations for form fields.</p> <p>ARSR was evaluated with focus on recommending values for fields of metadata forms.<br> The evaluation was performed with two sets of association rules (R1 and R2).<br> <strong>R1</strong> was primarily used to assess the recommendation performance.<br> <strong>R2</strong> served as an alternative and led to similar results.</p> <p>This dataset contains the raw data ("<strong>collected</strong>", JSON format), generated during the evaluation.<br> It includes i.a. input (populated fields and target field), expected output, and the top 40 generated recommendations for each test combination.</p> <p>In addition, the processed data ("<strong>analysed</strong>", CSV format) is provided.<br> It is based on the raw data and is used to calculate metrics and plot the results.</p> <p>The <strong>source code</strong> for ARSR and the evaluation is available on <a href="https://gitlab.com/dlr-dw/arsr">GitLab (gitlab.com)</a>.</p> <p> </p> <p><em>Note:</em><br> To perform the analysis on the raw data (collected) yourself, make sure to follow the setup instruction in the evaluation repository first.<br> More specifically, install dependencies and unzip "data/cedar/test-instances.zip" so that URI mappings can be accessed.<br> Then follow the instructions provided by the README file in the raw data archives (e.g. collected-R1.zip).</p>
ArsR transcriptional regulator mediated attenuated mechanism by regulating self and outer membrane protein in Brucella
<p><span>The ArsR family transcriptional regulators are widely distributed in microorganisms, including in the important intracellular pathogen <i>Brucella</i>. ArsR proteins are implicated in numerous biological processes. However, the specific roles of ArsR family members in <i>Brucella</i> remain obscure. Here we show that ArsR3 (BSS2_RS07325) is required for <i>Brucella</i> survival both under stress <i>in vitro</i> conditions and in a murine infection model<i> in vivo</i>. ArsR3 autoregulate its own expression to maintain metal ion homeostasis to benefit bacterial survival. Moreover, ArsR3 also regulates the production of virulence factor outer membrane protein 25D (Omp25D) which is key for the survival of <i>Brucella</i> under stress conditions. Significantly, ArsR3 deletion strain attenuated in a murine infection model<i> in vivo</i>. Altogether, our findings reveal a unique mechanism in which the ArsR family member ArsR3 autoregulates its expression and also modulates Omp25D expression to maintain metal ion homeostasis and virulence in <i>Brucella</i>.</span></p>
ArsR transcriptional regulator mediated attenuated mechanism by regulating self and outer membrane protein in Brucella
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The Helicobacter pylori Methylome is Acid-Responsive due to Regulation by the Two-Component System ArsRS and the Type I DNA Methyltransferase HsdM1 (HP0463)
GEO Series GSE241991. Helicobacter pylori. 6 samples. Type: Other.
Characterization of the ArsRS regulon of Helicobacter pylori
GEO Series GSE4293. Helicobacter pylori. 4 samples. Type: Expression profiling by array.
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