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304 results for “Adenovirus”
Deep splicing plasticity of the human adenovirus type 5 transcriptome as a driver of virus evolution nanopore data 48hpi
<p>Adenovirus infected MRC5 cells direct RNA sequencing of the mRNA using nanopore. From the paper Deep splicing plasticity of the human adenovirus type 5 transcriptome as a driver of virus evolution. Both the uncorrected fastq files and the lordec corrected files together with the normalised illumina data used to correct the nanpore data are here.</p>
AYUKA Genotyper Databases - Human Adenovirus (HAdV)
<p>Database files for several k-lenghts to be used in the AYUKA method to classify adenovirus genotypes</p>
Shift in Circulating Human Adenovirus Species Leading to Nationwide Outbreak - China, January 2023-August 2024
<p><span>Detailed methodologies and data quality control standards are provided</span><span> in the supplementary materials</span></p>
Adenovirus D26 Structural Model at Atomic Resolution
<p>Adenovirus D26 structural model at atomic resolution. This structural model has been constructed in UCSF Chimera software putting together all the structures that compose Adenovirus D26 using cryoEM reconstructions and pdb structures. By Dr. Victor Padilla-Sanchez, PhD from Washington Metropolitan University. Email: drvictorpadilla@aol.com</p>
Human adenovirus serotype 5 infection dysregulates cysteine, purine, and unsaturated fatty acid metabolism in fibroblasts
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Phylogenetic and recombination analysis of adenovirus isolates reveals discordance between serotype and phylogeny: Multiple sequence alignments
<p><strong>Background</strong></p> <p>Human adenovirus (HAdV) infections are caused by seven mastadenovirus species (A-G) and are the source for a variety of pathologies including gastrointestinal, respiratory, neurological, and ocular disease. While HAdV-D is the most common cause of adenovirus ocular infections, human adenoviruses B and E have also been isolated from the eye. </p> <p><strong>Results</strong></p> <p>In the course of classifying three new atypical ocular adenovirus samples, taken from the vitreous humor, we found that all three isolates were HAdV-B species, with isolate BP-AdV1 sorting with the B1 clade, and isolates BP-AdV2 and BP-AdV3 grouping into the B2 clade. The three Bascom Palmer HAdV-B genomes were then combined with over 300 HAdV-B genome sequences, including 9 ocular HAdV-B genome sequences. The whole genome phylogenetic analysis showed that 9 of the 11 ocular sequences grouped into the B1 clade, forming two clusters within B1. Attempts to categorize the penton, hexon and fiber serotypes using phylogeny of the three Bascom Palmer samples were inconclusive due to incongruence between serotype and phylogeny in the dataset. Recombination analysis using a subset of HAdV-B strains to generate a hybridization network detected recombination between non-human primate and human derived strains, recombination between one HAdV-B strain and the HAdV-E outgroup and limited recombination between the B1 and B2 clades. </p> <p><strong>Conclusions</strong></p> <p>The discordance between serotype and phylogeny detected in this study suggests that the current penton/hexon/fiber-based classification mechanism does not accurately describe the natural history and phylogenetic relationships amongst adenoviruses. A new adenovirus strain classification strategy may be beneficial to the field.</p>
Shift in Circulating Human Adenovirus Species Leading to Nationwide Outbreak - China, January 2023-August 2024
<p><span>The list of pathogens detected by the tNGS used in this study</span></p>
A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-ge
ClinicalTrials.gov study NCT03964415. IPD Sharing: YES. Countries: 9. Publications: 1.
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Adenovirus Serotype 26 Based Respiratory Syncytial Virus Pre-fusion (Ad26.RSV.Pre-F) Vaccine in RSV-Seronegative Toddlers 12 to 24
ClinicalTrials.gov study NCT03606512. IPD Sharing: Not stated. Countries: 8. Publications: 1.
A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV
ClinicalTrials.gov study NCT03339713. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Chimpanzee Adenovirus and Self-Amplifying mRNA Prime-Boost Prophylactic Vaccines Against SARS-CoV-2 in Healthy Adults
ClinicalTrials.gov study NCT04776317. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation
ClinicalTrials.gov study NCT05179057. IPD Sharing: NO. Countries: 6. Publications: 1.
Ebola Sudan Chimpanzee Adenovirus Vector Vaccine in Healthy Adults
ClinicalTrials.gov study NCT04041570. IPD Sharing: NO. Countries: 1. Publications: 6.
Phase 2 Study to Evaluate Brincidofovir for the Prevention of Adenovirus Disease
ClinicalTrials.gov study NCT01241344. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death
ClinicalTrials.gov study NCT03003676. IPD Sharing: Not stated. Countries: 2. Publications: 1.
A Study to Evaluate a Range of Dose Levels of an Adenovirus Serotype 26 (Ad26.RSV.preF)-Based Vaccine in Older Adults
ClinicalTrials.gov study NCT04453202. IPD Sharing: YES. Countries: 1. Publications: 1.
ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK Virus
ClinicalTrials.gov study NCT01570283. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease
ClinicalTrials.gov study NCT04908683. IPD Sharing: YES. Countries: 14. Publications: 1.
Data from: Alpha-defensin binding expands human adenovirus tropism
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Phylogenetic and recombination analysis of adenovirus isolates reveals discordance between serotype and phylogeny: Multiple sequence alignments
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.