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11 results for “Aggregatibacter actinomycetemcomitans”

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dryad36/100

Computationally modelled structure of type IV pilus PilA of Aggregatibacter actinomycetemcomitans

<p>Some bacterial type IV pili structures have been determined with Cryo-EM, X-ray diffraction or similar method. The type IVa pilus PilA of <em>Aggregatibacter actinomycetemcomitans</em>, an oral pathogen, shares sequence identity with other bacterial type IVa pili. To understand the structure of AaPilA at the molecular level, we performed computational modeling studies. To model the filament, we utilized the GalaxyGemini web server using different monomer conformations from molecular dynamics simulations as a seed; then, we extended the structure to 14-mer by employing the cryo-EM map file of type IV pilus from enterohemorrhagic <em>E. coli</em>. The structures were predicted for a full-length monomer PilA_D7S, N-terminally truncated monomer PilA_D7S_Δ1-27 and 14-homo-oligomer PilA_D7S_14mer. PilAD7S_Δ1-27 and PilAD7S share the same secondary structural elements: an N-terminal α-helix, four antiparallel β-strands, a hypervariable segment and a flexible C-terminus. The homo-oligomeric PilAD7S from our computational model resembles the interface seen in the cryo-EM structure of <em>N. meningitidis</em> type IV pili.</p>

opencc-zeroNov 2022View details →
dryad36/100

Computationally modelled structure of type IV pilus PilA of Aggregatibacter actinomycetemcomitans

Open the record for dataset details and reuse information.

publicNov 2022View details →
geo24/100

Effect of infection with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis on primary murine bone marrow-derived dendritic cells

GEO Series GSE41383. Mus musculus. 9 samples. Type: Expression profiling by array.

openGEO-OpenJan 2013View details →
geo24/100

Transcriptome analysis of Aggregatibacter actinomycetemcomitans strains isolated from the same individual during short term persistent infections using a pan-genome microarray

GEO Series GSE43074. Aggregatibacter actinomycetemcomitans. 16 samples. Type: Expression profiling by array.

openGEO-OpenDec 2013View details →
geo24/100

Transcriptome analysis of Aggregatibacter actinomycetemcomitans serotype b strains of JP2 and non-JP2 genotypes using a pan-genome microarray

GEO Series GSE38943. Aggregatibacter actinomycetemcomitans. 10 samples. Type: Expression profiling by array.

openGEO-OpenSep 2012View details →
geo24/100

Comparative genomic analysis of Aggregatibacter actinomycetemcomitans strains during short term persistent infections using a pan-genome microarray

GEO Series GSE42953. Aggregatibacter actinomycetemcomitans. 16 samples. Type: Genome variation profiling by array.

openGEO-OpenDec 2013View details →
geo24/100

Comparative genomic analysis of Aggregatibacter actinomycetemcomitans of JP2 and non-JP2 genotypes using a pan-genome microarray

GEO Series GSE39143. Aggregatibacter actinomycetemcomitans. 38 samples. Type: Genome variation profiling by array.

openGEO-OpenSep 2012View details →
geo24/100

Effect of Catecholamines on the Dental Pathogen Aggregatibacter actinomycetemcomitans

GEO Series GSE68749. Aggregatibacter actinomycetemcomitans. 9 samples. Type: Expression profiling by array.

openGEO-OpenMay 2015View details →
zenodo24/100

Trees and Roary output for Adaptation by ancient horizontal acquisition of butyrate metabolism genes in Aggregatibacter actinomycetemcomitans

<p>Supporting data for publication.&nbsp;</p> <ol> <li>Raw Trees for Figure 1 and supplementary figures 2 and 3.</li> <li>Roary presence absence output.</li> </ol>

opencc-by-4.0Dec 2020View details →
ClinicalTrials.gov24/100

Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis

ClinicalTrials.gov study NCT02010307. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo20/100

Crosstalk between Streptococcus mutans and Aggregatibacter actinomycetemcomitans in dual-species biofilms.

GEO Series GSE75019. Streptococcus mutans; Aggregatibacter actinomycetemcomitans. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2017View details →

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