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34 results for “Akkermansia muciniphila”
Akkermansia muciniphila reduces diet-induced susceptibility to Listeria monocytogenes infection
<p>A high fat (HF) diet decreases levels of <em>Akkermansia muciniphila</em> in the gut and reduces resistance to the foodborne pathogen <em>Listeria monocytogenes</em>. We demonstrate that short-term gavage with <em>A. muciniphila</em> increases resistance to oral and systemic <em>L. monocytogenes</em> infection in mice fed a HF diet. <em>A. muciniphila</em> normalized diet-induced inflammation in the gut and liver prior to infection and reduced inflammatory cell infiltration in the ileum to levels similar to mice fed a low fat diet. <em>A. muciniphila</em> administration had minimal impact upon the microbiota and microbial metabolites and did not affect individual taxa or impact the Bacteroidetes to Firmicutes ratio. In summary, <em>A. muciniphila</em> increased resistance to <em>L. monocytogenes</em> infection in mice fed a HF diet, through normalising immune/physiological effects that more closely resembled mice fed a LF diet. The findings suggest an interaction between <em>A. muciniphila</em> and the host to reverse the effects of a westernized diet in this model.</p>
The Efficacy of Pasteurised Akkermansia Muciniphila in Healthy Medical Workers
ClinicalTrials.gov study NCT05738746. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia
ClinicalTrials.gov study NCT05114018. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Evaluation of the Effects Associated With the Administration of Akkermansia Muciniphila on Parameters of Metabolic Syndrome
ClinicalTrials.gov study NCT02637115. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Effect of Akkermansia Muciniphila WST01 Strain in Overweight or Obese Patients With Type 2 Diabetes
ClinicalTrials.gov study NCT04797442. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.
ClinicalTrials.gov study NCT05720299. IPD Sharing: NO. Countries: 1. Publications: 0.
Akkermansia muciniphila Membrane Protein Improves Cognitive Function in Aged Mice by Reducing IL-6 Expression
GEO Series GSE162123. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Ascorbic acid increases CD8+ T cells by binding Myh9 protein and enriching gut microbiota Akkermansia muciniphila, improves cognitive levels in middle-aged mice [scRNA-seq]
GEO Series GSE262964. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocel
GEO Series GSE242468. Mus musculus. 10 samples. Type: Other.
Akkermansia muciniphila outer membrane protein Amuc_0904 promotes goblet cell differentiation
GEO Series GSE288821. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Acute gastrointestinal permeability after traumatic brain injury in mice precedes a bloom in Akkermansia muciniphila supported by intestinal hypoxia
GEO Series GSE239472. Mus musculus. 89 samples. Type: Other.
Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocel
GEO Series GSE242469. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing analysis of doxorubicin-treated mice after administration with Akkermansia muciniphila
GEO Series GSE276172. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Intestinal Akkermansia muciniphila complements the efficacy of PD1 therapy in MAFLD-related hepatocellular carcinoma
GEO Series GSE242470. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation
GEO Series GSE233857. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Intestinal Akkermansia Muciniphila in Prostate Cancer
ClinicalTrials.gov study NCT06242509. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia
ClinicalTrials.gov study NCT06974266. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Study to Evaluate the Effect of Pasteurized Akkermansia Muciniphila (pAkk) on Complaints Related to IBS
ClinicalTrials.gov study NCT05348642. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Weight Loss Effect of Akkermansia Muciniphila in Obese Patients
ClinicalTrials.gov study NCT06780007. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Akkermansia Muciniphila Akk11 on Metabolic and Gut Health in Overweight and Obese Subjects
ClinicalTrials.gov study NCT06653101. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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