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327 results for “Anorexia nervosa”
BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 2: All axial slices of sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients.
<p>Results from the sLORETA imaging indicates decreased neuronal activation within the Left<br> Fusiform Gyrus located in the Temporal lobe and Parrahippocampal gyrus, which is located in the<br> Limbic Lobe (Table 1). This correlates with other fMRI findings where patients with early onset<br> AN have exhibited reduced unilateral blood flow in the temporal lobe. The Parahippocampal and<br> Fusiform Gyri are centers that process emotions. Previous studies in which these regions have<br> shown activation involve women that have distorted perceptions of their bodies from a cognitive<br> perspective (Santel et al., 2006). It is apparent from our findings that the Fusiform Gyrus may play<br> a vital role in the processing of visual appearance of the human body. There is also a correlation<br> with the somatosensory limbic pathway in the limbic lobe, due to the similarity of function.</p>
BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 1: sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients relative to Control participants
<p>The findings of the sLORETA analysis indicated that, the difference is statistically<br> significant (p=0.03) using a one-tailed t-test: Anorexia > Controls. The brains of the patients with<br> Anorexia Nervosa illustrated decreased neuronal activity in the Left Fusiform Gyrus and the Left<br> Parahippocampal Gyrus (p=0.03) in the resting-state brains when Anorexia Patients were sitting for<br> 3min, as compared to the Controls sitting for 3minutes.</p>
Psilocybin therapy for females with anorexia nervosa: A phase 1, open label, feasibility study
<p class="MsoNoSpacing">Anorexia nervosa (AN) is a deadly illness with no proven treatments to reverse core symptoms and no FDA-approved medications. Novel treatments are urgently needed to improve clinical outcomes. In this open-label feasibility study, 10 adult female participants (<em>m</em> BMI 19.7 kg/m<sup>2</sup>; SD 3.7) who met DSM 5 criteria for AN or pAN (partial remission) were recruited to a study conducted at an academic clinical research institute. Participants received a single 25mg dose of synthetic psilocybin combined with psychological support. The primary aim was to assess safety, tolerability, and feasibility at post-treatment via incidences and occurrences of adverse events (AEs) and clinically significant changes in: ECG, laboratory tests, vital signs and suicidality. There were no clinically significant changes in ECG, vital signs, or suicidality. Two participants developed asymptomatic hypoglycemia at post-treatment, which resolved within 24 hours. There were no other clinically significant changes in laboratory values. All AEs were mild and transient in nature. Participants' qualitative perceptions suggest that the treatment was acceptable for most participants. <span>R</span>esults suggest that psilocybin therapy is safe, tolerable, and acceptable for female AN, a promising finding given physiological dangers and problems with treatment engagement.</p> <p class="MsoNoSpacing">ClinicalTrials.gov Identifier: NCT04661514</p>
Comparing the Effectiveness of Two Therapies to Treat Signs of Anorexia Nervosa in Adolescents
ClinicalTrials.gov study NCT00418977. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Hormonal Factors in the Treatment of Anorexia Nervosa
ClinicalTrials.gov study NCT01121211. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effectiveness of Olanzapine Versus Placebo in Treating Outpatients With Anorexia Nervosa
ClinicalTrials.gov study NCT00692185. IPD Sharing: Not stated. Countries: 1. Publications: 1.
An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa
ClinicalTrials.gov study NCT06518941. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
Bone Loss in Women With Anorexia Nervosa
ClinicalTrials.gov study NCT00089843. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Trial of Quetiapine in Anorexia Nervosa
ClinicalTrials.gov study NCT00518973. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect Of Biomechanical Stimulation On Skeletal Health In Adolescent And Young Women With Anorexia Nervosa
ClinicalTrials.gov study NCT01100567. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Amino Acids in Patients With Anorexia Nervosa: Double-blind Randomized Study Versus Placebo
ClinicalTrials.gov study NCT05290285. IPD Sharing: NO. Countries: 1. Publications: 6.
CBT Effects on Neural, Physiological, and Attentional Responses in Anorexia Nervosa
ClinicalTrials.gov study NCT07037017. IPD Sharing: YES. Countries: 1. Publications: 0.
Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
ClinicalTrials.gov study NCT03928028. IPD Sharing: NO. Countries: 1. Publications: 9.
Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa
ClinicalTrials.gov study NCT00310791. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Olanzapine in the Treatment of Patients With Anorexia Nervosa
ClinicalTrials.gov study NCT00260962. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa
ClinicalTrials.gov study NCT01170117. IPD Sharing: Not stated. Countries: 2. Publications: 2.
The Role of Lactobacillus Reuteri in Children and Adolescents With Anorexia Nervosa
ClinicalTrials.gov study NCT02004288. IPD Sharing: NO. Countries: 1. Publications: 1.
Virtual Reality-Based Attention Bias Modification Training for Adolescents With Anorexia Nervosa
ClinicalTrials.gov study NCT04786951. IPD Sharing: NO. Countries: 1. Publications: 6.
Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa
ClinicalTrials.gov study NCT00288574. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Double-blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa
ClinicalTrials.gov study NCT00140426. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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