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391 results for “Antiretroviral therapy”
Population size, HIV prevalence, and antiretroviral therapy coverage among key populations in sub-Saharan Africa: collation and synthesis of survey data 2010-2023
<p>This dataset contains surveillance study estimates for population size, HIV prevalence, and ART coverage among female sex workers (FSW), men who have sex with men (MSM), people who inject drugs (PWID), and transgender men and women (TGM/W) from 2010-2023. It was created to support the UNAIDS Estimates Key Population Workbook for use by HIV estimates teams in sub-Saharan Africa. Key population surveillance reports, including Ministry of Health-led biobehavioural surveys, mapping studies, and academic studies were used to populate the database.</p> <p>The dataset was populated using existing key population size estimate databases including:</p> <ul> <li>UNAIDS Key Population Atlas</li> <li>US Centers for Disease Control and Prevention surveillance database</li> <li>Global Fund against HIV/AIDS, TB, and Malaria surveillance database</li> <li>Global.HIV database</li> <li>Systematic review databases among MSM (<a href="https://pubmed.ncbi.nlm.nih.gov/31601542/" target="_blank" rel="noopener">Stannah et al, 2019</a> and <a href="https://pubmed.ncbi.nlm.nih.gov/37453439/" target="_blank" rel="noopener">Stannah et al., 2023</a>) and PWID (<a href="https://pubmed.ncbi.nlm.nih.gov/36996857/" target="_blank" rel="noopener">Degenhardt et al., 2023</a>)</li> </ul> <p><br>and was additionally supplemented by a literature review of peer-reviewed and grey literature sources.</p> <p>The data can be <a href="https://shiny.dide.ic.ac.uk/kp-data/" target="_blank" rel="noopener">explored in this web application</a> and the <a href="https://www.medrxiv.org/content/10.1101/2022.07.27.22278071v3" target="_blank" rel="noopener">accompanying manuscript can be found here</a></p>
Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to
ClinicalTrials.gov study NCT01618305. IPD Sharing: YES. Countries: 7. Publications: 1.
Vacc-4x + Lenalidomide vs. Vacc-4x +Placebo in HIV-1-infected Subjects on Antiretroviral Therapy (ART)
ClinicalTrials.gov study NCT01704781. IPD Sharing: NO. Countries: 1. Publications: 4.
Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants
ClinicalTrials.gov study NCT03048422. IPD Sharing: YES. Countries: 9. Publications: 5.
Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho
<p>These are pseudo-anonymised data from the SESOTHO randomised trial: "Switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL – a multicenter, parallel-group, open-label, randomized clinical study in rural Lesotho". There are two datasets, one containing baseline data (one row per participant) and one containing longitudinal viral load data (one row per participant per visit). The data dictionary explains the data available in each dataset. Between August 2017 and August 2019, 80 eligible and consenting participants were enrolled from eight health facilities in four districts of Lesotho, and followed up for nine months. The protocol was published, DOI: 10.1186/s12879-018-2979-y</p>
Dolutegravir in Real Life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho
<p>Pseudonymized dataset for the accepted manuscript "<em>Dolutegravir in Real Life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho</em>"</p>
Underlying qualitative data for: "What went wrong? A qualitative exploration of the determinants of poor antiretroviral therapy adherence and retention in care among pregnant and postpartum women in the Uganda WiseMama randomized controlled trial"
<p>This dataset is the underlying qualitative data for the paper entitled: "What went wrong? A qualitative exploration of the determinants of poor antiretroviral therapy adherence and retention in care among pregnant and postpartum women in the Uganda WiseMama randomized controlled trial"</p>
HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov study NCT02437110. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Interferon Alpha 2b Intensification in HIV-Positive Individuals on Antiretroviral Therapy
ClinicalTrials.gov study NCT01295515. IPD Sharing: NO. Countries: 1. Publications: 4.
Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB
ClinicalTrials.gov study NCT01751568. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Diagnosis of HIV and Early Antiretroviral Therapy Initiation Among HIV-1 Infected Infants
ClinicalTrials.gov study NCT03133728. IPD Sharing: NO. Countries: 1. Publications: 1.
Quantifying Drug Adherence and Drug Exposure to Antiretroviral Therapy
ClinicalTrials.gov study NCT02012621. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Study to Evaluate Effects of Vorinostat and HXTC on Persistent HIV-1 Infection in HIV-Infected Subjects Started on Antiretroviral Therapy (ART)
ClinicalTrials.gov study NCT03212989. IPD Sharing: NO. Countries: 1. Publications: 1.
Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma
ClinicalTrials.gov study NCT01352117. IPD Sharing: UNDECIDED. Countries: 6. Publications: 5.
Aspirin and Antiretroviral Therapy in HIV Infected Patients
ClinicalTrials.gov study NCT00783614. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy
ClinicalTrials.gov study NCT02471430. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease
ClinicalTrials.gov study NCT04552795. IPD Sharing: YES. Countries: 1. Publications: 0.
Home Assessment and Initiation of Antiretroviral Therapy for HIV in Malawi
ClinicalTrials.gov study NCT01414413. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
ClinicalTrials.gov study NCT01957865. IPD Sharing: YES. Countries: 1. Publications: 3.
A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen
ClinicalTrials.gov study NCT00931463. IPD Sharing: Not stated. Countries: 17. Publications: 4.
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OpenNeuro
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