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82 results for “Aspergillus nidulans”
SvfA, survival factor A, contributes to Aspergillus nidulans pathogenicity
<p>Supplementary information-SvfA, survival factor A, contributes to <em>Aspergillus</em> <em>nidulans</em> pathogenicity</p>
Data from: A pair of nonoptimal codons are necessary for the correct biosynthesis of the Aspergillus nidulans urea transporter, UreA
Both in prokaryotic and eukaryotic genomes synonymous codons are unevenly used. Such differential usage of optimal or nonoptimal codons has been suggested to play a role in the control of translation initiation and elongation, as well as at the level of transcription and mRNA stability. In the case of membrane proteins codon usage has been proposed to assist in the establishment of a pause necessary for the correct targeting of the nascent chains to the translocon. In this work, using as model UreA, the Aspergillus nidulans urea transporter, we show that the synonymous mutation of a pair of nonoptimal codons coding for amino acids situated at the limit between the N-terminus and the first transmembrane segment are necessary for its proper biogenesis at 37ºC. This effect is less relevant at 25ºC. These codons presumably regulate translation rate in order to allow for the correct interaction of UreA-translating ribosomes with factors required for the targeting and/or folding of the protein, in a very early stage of the biosynthesis process. Whether this mechanism would affect other proteins, remains to be determined.
Fig. 3 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 3. The key NOESY correlations of compounds 1–4.
Fig. 2. Key 1H–1H in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 2. Key 1H–1H COSY and HMBC correlations of compounds 1–4.
Fig. 5 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 5. The experimental and calculated ECD spectra of compound 4.
Fig. 1 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 1. Chemical structures of compounds 1–10.
Fig. 4 in Prenylated quinolinone alkaloids and prenylated isoindolinone alkaloids from the fungus Aspergillus nidulans
Fig. 4. Experiment ECD spectra of compounds 1 and 2.
Data from: A pair of nonoptimal codons are necessary for the correct biosynthesis of the Aspergillus nidulans urea transporter, UreA
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Data from: The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans
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Data from: Air-borne genotype by genotype indirect genetic effects are substantial in the filamentous fungus Aspergillus nidulans
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International Space Station conditions alter genomics proteomics and metabolomics in Aspergillus nidulans
The first global genomic proteomic and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the International Space Station (ISS) is reported. The investigation included the A. nidulans wild-type and three mutant strains two of which were genetically engineered to enhance secondary metabolite production. Whole genome sequencing revealed that ISS conditions altered the A. nidulans genome in specific regions. In strain CW12001 which features overexpression of the secondary metabolite global regulator laeA ISS conditions induced the loss of the laeA stop codon. Differential expression of proteins involved in stress response carbohydrate metabolic processes and secondary metabolite biosynthesis was also observed. ISS conditions significantly decreased prenyl xanthone production in the wild-type strain and increased asperthecin production in LO1362 and CW12001 which are deficient in a major DNA repair mechanism. These data provide valuable insights into the adaptation mechanism of A. nidulans to spacecraft environments.
Aspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
GEO Series GSE42732. Aspergillus nidulans FGSC A4; Aspergillus nidulans. 18 samples. Type: Expression profiling by array.
Aspergillus nidulans strains R21 and ∆gprH during growth in minimal media (MM) and carbon starvation
GEO Series GSE65282. Aspergillus nidulans; Aspergillus nidulans FGSC A4. 12 samples. Type: Expression profiling by array.
RNA sampling from a chemically diverse set of solid agar cultures of Aspergillus nidulans
GEO Series GSE39993. Aspergillus nidulans FGSC A4; Aspergillus nidulans. 8 samples. Type: Expression profiling by array.
Aspergillus nidulans strains TNO2a3, ∆snfA and ∆schA grown on avicel as sole carbon source
GEO Series GSE47810. Aspergillus nidulans; Aspergillus nidulans FGSC A4. 16 samples. Type: Expression profiling by array.
Amphotericin B, CdCl2 and Congo Red stress responses in a delta-atfA mutant and a control Aspergillus nidulans strains.
GEO Series GSE134562. Aspergillus nidulans. 8 samples. Type: Expression profiling by array.
Aspergillus nidulans : Control (Wt) vs. ΔcnaA or alcApkcAΔcnaA
GEO Series GSE48535. Aspergillus nidulans; Aspergillus nidulans FGSC A4. 12 samples. Type: Expression profiling by array.
Unraveling the Gene Regulatory Networks of the Global Regulators VeA and LaeA in Aspergillus nidulans
GEO Series GSE217820. Aspergillus nidulans. 21 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Aspergillus nidulans ∆pkaA strain grown on avicel as sole carbon source
GEO Series GSE70917. Aspergillus nidulans FGSC A4; Aspergillus nidulans. 6 samples. Type: Expression profiling by array.
Newly identified Aspergillus nidulans PKA targets play a role in carbon-catabolite repression
GEO Series GSE116579. Aspergillus nidulans. 4 samples. Type: Expression profiling by high throughput sequencing.
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