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2 results for “Axonal calcium imaging”
CA3 axonal calcium imaging
<p>Memorizing locations that are harmful or dangerous is a key capability of all organisms, and requires an integration of affective and spatial information. In mammals, the dorsal hippocampus mainly processes spatial information, while the intermediate to ventral hippocampal divisions receive affective information via the amygdala. However, how spatial and aversive information is integrated is currently unknown.</p> <p>To address this question, we recorded the activity of hippocampal long-range CA3 axons at single axon resolution in mice forming an aversive spatial memory. We show that intermediate CA3 to dorsal CA3 (i-dCA3) projections rapidly overrepresent areas preceding the location of an aversive stimulus, due to a spatially selective addition of newly place-coding axons, followed by a spatially nonspecific stabilization. This sequence significantly improves the encoding of location by the i-dCA3 axon population.</p> <p>These results suggest that i-dCA3 axons transmit a precise, denoised and stable signal indicating imminent danger to dorsal hippocampus.</p>
CA3 axonal calcium imaging
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DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.