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111 results for “BMP signalling”
Data from: Opposing roles for Bmp signalling during the development of electrosensory lateral line organs
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LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling
<p>This dataset represents the raw data that gave rise to the study by Vickers et al., 2020 in Scientific Reports (<a href="https://doi.org/10.1038/s41598-020-66862-5">DOI: 10.1038/s41598-020-66862-5</a>). Please refer to the original publication regarding experimental design and methodological details of data acquisition and analysis. Below we supply information on the provided metadata files (which, in turn, refer to individual raw data files), and essential details on the specific data formats:</p> <ol> <li>raw data is organized in the datasets related to Figs. 1, 2, 3, 4-E, 4F-H of the paper (Vickers et al., 2020);</li> <li>the metadata for each individual dataset, listing individual data filenames from the respective dataset, are stored in separate “.csv” files, one per each dataset. Field separator: comma;</li> <li>individual metadata files for each dataset are described in the master metadata file “metadata_master.csv”;</li> <li>patch clamp recordings (Figs. 1-3, 4F-H) are provided as “.dat” files, unmodified from the original version created by the acquisition software PatchMaster (HEKA Elektronik, Germany). Besides original PatchMaster software, these files can be imported using one of the following methods: I) via Igor Pro extension bpc_ReadHeka.xop (for 32-bit Igor Pro versions 5.xx - 6.37) by Holger Taschenberger (<a href="https://www.wavemetrics.com/project/bpc_ReadHeka">https://www.wavemetrics.com/project/bpc_ReadHeka</a>); II) via Python script by Luke Campagnola (<a href="https://github.com/campagnola/heka_reader">https://github.com/campagnola/heka_reader</a>); III) via Matlab script HEKA PatchMaster Importer by Christian Keine (<a href="https://github.com/ChristianKeine/HEKA_Patchmaster_Importer">https://github.com/ChristianKeine/HEKA_Patchmaster_Importer</a>);</li> <li>exact names of patch-clamp traces used for each Figure are provided in the corresponding “.csv” metadata files. Traces names are given in the format: ExperimentName_1_SeriesNumber_SweepNumber_ChannelNumber. When “*” is used, it means that every sweep of corresponding series was used for analysis (e.g. Nov0317_1_13_*_2 all sweeps from series number 13 were used). Description in the metadata files also specifies which series correspond to which experimental epoch (baseline or plasticity testing), and to pharmacological manipulations, if applicable;</li> <li>widefield fluorescent images of coronal brain slices, cropped images of subregions in the primary auditory cortex used for quantification, and confocal Z-stacks zooming onto single nuclei of neurons stained for FISH experiments (Fig. 4A-E) were converted into composite TIFF format from the proprietary formats of Axioscan Z1 slide scanning microscope and LSM700 confocal microscope (Carl Zeiss). TIFF format is readable by FIJI/ImageJ (<a href="https://fiji.sc/">https://fiji.sc/</a> or <a href="https://imagej.net/Fiji/Downloads">https://imagej.net/Fiji/Downloads</a>). Pixel resolution and voxel sizes are embedded in these TIFF files. Assignment of the color channels for each image is described in the metadata file.</li> </ol>
Impact of BMP and WNT signaling modulation on mesendoderm progenitor cells specification from hPSCs in 3D culture conditions
GEO Series GSE184302. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Operation of the atypical canonical BMP signaling pathway during human odontogenesis
GEO Series GSE179474. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways
GEO Series GSE162289. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Unexpected contribution of fibroblasts to the muscle lineage during foetal myogenesis and role of BMP signalling in this process
GEO Series GSE166981. Gallus gallus. 3 samples. Type: Expression profiling by high throughput sequencing.
Distinct BMP-Smad Signaling Outputs Confer Diverse Functions in Dental Mesenchyme
GEO Series GSE297138. Mus musculus. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Constant inhibition of local BMP signaling contributes to recovery of mucociliary epithelium from Tracheobronchopathia Osteochondroplastica (TO)-associated pathophysiology via basal cell restoration
GEO Series GSE153290. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
BMPR1A-mediated BMP signalling ensures correct mitosis-to-meiosis transition in mouse fetal ovarian germ cells, in vivo
GEO Series GSE268565. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Epigenomic analyses of FOXA1-mediated enhancer reprogramming to control tumor subtype plasticity through HH-BMP-FOXA1 signalling feedback between urothelial tumor and stromal fibroblasts [RNA-seq]
GEO Series GSE141350. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche
GEO Series GSE212601. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish
GEO Series GSE282061. Danio rerio. 10 samples. Type: Expression profiling by high throughput sequencing.
Bmp signaling maintains a mesoderm progenitor cell state in the mouse tailbud
GEO Series GSE101810. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
TNF Drives Aberrant BMP Signaling to Induce Endothelial and Mesenchymal Dysregulation in a Transgenic Model of Pulmonary Hypertension
GEO Series GSE279244. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The Pitx2:miR-200c/141:noggin pathway regulates BMP signaling and ameloblast differentiation
GEO Series GSE48583. Mus musculus. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
BMP signaling in mouse embryonic stem cells (ESCs) in the naïve and primed pluripotent states [ChIP-Seq]
GEO Series GSE70579. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
GEO Series GSE213930. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
BMP signaling cooperates with GATA factors to govern stage-specific gene expression during erythroid differentiation
GEO Series GSE74483. Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
GEO Series GSE242524. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling
GEO Series GSE212352. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.