Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
72
datasets available to search
ShareScore release 0.9.0
Dataset results
72 results for “BPA”
Dataset of BPA concentration levels in food from the second French total diet study
<p><strong>Information about the BPA data set</strong></p> <p> </p> <p><em>1. Description of the total diet study 2 (TDS2) and the BPA study</em></p> <p>The French TDS2 consisted in collecting food products representative of the French population's consumption. This kind of study has been recommended by the World Health Organization (WHO) and the European Food Safety Authority (EFSA) and are implemented with standardized methods. The collected foods were prepared “as consumed” to take account of the population’s common practices, they were combined as composite/pooled samples and were analyzed for chemicals of public health interest. The aims of the TDS2 were to assess the population's exposure to the analyzed substances and the risk for the substances for which reference values exist. To achieve these objectives nearly 20,000 food products were purchased in about 30 cities throughout France (metropolitan territory) and prepared to constitute 1,319 samples corresponding to 212 food items (Sirot <em>et al</em>, 2009). Each sample was composed of 15 sub-samples of the same food and mass, considering different brands and consumer food preferences. All samples, except a few, were collected twice during the TDS to reflect the potential seasonal variability in composition or contamination. Some foods were also purchased in different regions of France because of the potential regional differences in contamination.</p> <p>Analysis of BPA contamination levels in food was not initially planned in the TDS2, and was conducted in a second wave of analyses. The laboratory (LABERCA) in charge of analysis verified that sample containers did not contain BPA. Some TDS samples had not a sufficient weight to be analyzed so only 207 food items were considered.</p> <p> </p> <p><em>2. Description of the data set</em></p> <p>The dataset presents the BPA contamination levels at the food item level, i.e. seasonal sample values were averaged at the regional level and then regional sample values were averaged to represent the national level. The original regional dataset is available in French at the following URL <a href="https://www.data.gouv.fr/fr/datasets/r/4b911e97-368b-4b0e-8891-cecd81aa39bb">https://www.data.gouv.fr/fr/datasets/r/4b911e97-368b-4b0e-8891-cecd81aa39bb</a>.</p> <p>The analytical methods and limits (limit of detection and quantification) are described in (Bemrah <em>et al</em> 2014).</p> <p> </p> <p>2.1. Pre-processing of concentration data</p> <p>Left censored data (concentration value below the analytical limits) were managed under 3 hypotheses:</p> <ul> <li>The lowerbound (LB) hypothesis: Concentrations below the LOD (undetected substances) were replaced by 0, and concentrations below the LOQ but above the LOD (known as "traces") were replaced by the LOD value;</li> <li>The middlebound (MB) hypothesis: Concentrations below the LOD were replaced by ½ LOD, and concentrations below the LOQ but above the LOD were replaced by ½ (LOD+LOQ) ;</li> <li>Upperbound (UB) hypothesis: Concentrations below the LOD were replaced by the LOD value, and concentrations below the LOQ but above the LOD were replaced by the LOQ.</li> </ul> <p> </p> <p>2.2. Thesaurus</p> <p>The variables of the dataset and their definitions were presented in the list below:</p> <ul> <li>family: name of the chemical group of the substance;</li> <li>subst: abbreviated name of the substance;</li> <li>subst_cn: complete name of the substance;</li> <li>unit: unit of the mean concentration value of the substance;</li> <li>mean_CONTA_LB: mean of the concentration values of sub-samples of the analyzed food calculated under the lower bound hypothesis;</li> <li>mean_CONTA_MB: mean of the concentration values of sub-samples of the analyzed food calculated under the middle bound hypothesis;</li> <li>mean_CONTA_UB: mean of the concentration values of sub-samples of the analyzed food calculated under the upper bound hypothesis;</li> <li>Food_code: identification number of the analyzed food;</li> <li>Food_group: food category of the analyzed food;</li> <li>Type_foods: analyzed food.</li> </ul>
Data for: Feeding frequency does not interact with BPA exposure to influence metabolism of behaviour in zebrafish (Danio rerio)
<p><span>Resource limitation can constrain energy (ATP) production, and thereby affect locomotion and behaviour such as exploration of novel environments and boldness. Consequently, ecological processes such as dispersal and interactions within and between species may be influenced by food availability. Energy metabolism, and behaviour are regulated by endocrine signaling, and may therefore be impacted by endocrine disrupting compounds (EDCs) such as bisphenol A (BPA) derived from plastic manufacture and pollution. It is important to determine the impacts of these novel environmental contexts to understand how human activity alters individual physiology and behaviour and thereby populations. Our aim was to determine whether BPA exposure interacts with feeding frequency to alter metabolism and behaviour. In a fully factorial experiment, we show that low feeding frequency reduced zebrafish (<em>Danio rerio</em>) mass, condition, resting metabolic rates, total distance moved and speed in a novel arena, as well as anxiety indicated by the number of times fish returned to a dark shelter. However, feeding frequency did not significantly affect maximal metabolic rates, aerobic scope, swimming performance, latency to leave a shelter, or metabolic enzyme activities (citrate synthase and lactate dehydrogenase). Natural or anthropogenic fluctuation in food resources can therefore impact energetics and movement of animals with repercussions for ecological processes such as dispersal. BPA exposure reduced LDH activity and body mass, but did not interact with feeding frequency. Hence, behaviour of adult fish is relatively insensitive to disruption by BPA. However, alteration of LDH activity by BPA could disrupt lactate metabolism and signalling and together with reduction in body mass could affect size-dependent reproductive output. BPA released by plastic manufacture and pollution can thereby impact conservation and management of natural resources. </span></p>
Extracció BPA 25012022-25032022
<p>Dataset derivat, mitjançant web-scraping, de la informació del butlletí de Perill d'Allaus (<a href="https://www.icgc.cat/Ciutada/Explora-Catalunya/Allaus/Butlleti-de-Perill-d-Allaus-BPA">https://www.icgc.cat/Ciutada/Explora-Catalunya/Allaus/Butlleti-de-Perill-d-Allaus-BPA</a>) de l’Institut Cartogràfic i Geològic de Catalunya (ICGC), utilitzada sota una llicència CC BY 4.0. Les dades s'han extret el día 12/04/2022.</p> <p>El dataset requereix processament adicional per tractar les dades.</p>
Metadata on environmental and fish bioaccessibility of phthalate esters and BPA from PE and PVC microplastics
<p>Water and fish bioaccessibility data in Tables S5 and S7 of the article entitled "Bioaccessibility of plastic-related compounds from polymeric particles in marine settings: Are microplastics the principal vector of phthalate ester congeners and bisphenol A towards marine vertebrates?" published in Science of the Total Environment 954 (2024) 176308</p>
Neonatal exposure to BPA, BDE-99, and PCB produces persistent changes in hepatic transcriptome associated with gut dysbiosis in adult mouse livers
<p class="western"><span><span><span><b>Background</b>. Recent evidence suggests that multigenic and complex environmentally modulated diseases result from early life exposure to toxicants at least partly via gut microbial influences. Environmental toxicants, polybrominated diphenyl ethers (PBDEs), and polychlorinated biphenyls (PCBs) are breast milk-enriched persistent organic pollutants (POPs) and thus remain a continuing threat to human health despite being banned from production. Recent findings focused on the liver developmental reprogramming capabilities from neonatal BPA exposure; however, little is known on how PBDEs and PCBs regulate the liver transcriptome with respect to the gut microbiome. </span></span></span></p> <p class="western"><span><span><span><b>Objectives</b>. We investigated whether the gut microbiome can be persistently reprogrammed with the liver following neonatal exposure to POPs, and whether microbial biomarkers associated with disease-prone changes in the hepatic epigenetic and transcriptomic landscape in adulthood. </span></span></span></p> <p class="western"><span><span><span><b>Methods. </b>C57BL/6 male and female mouse pups were orally administered vehicle, bisphenol A (BPA), BDE-99 (a breast milk-enriched PBDE congener), or the Fox River PCB mixture (an environmentally relevant PCB mixture), between postnatal day (PND) 2 to 4, once daily for three consecutive days. Tissues were collected at PND5 and PND60 for 16S rDNA sequencing and targeted metabolomics.</span></span></span></p> <p class="western"><span><span><span><b>Results</b>. Neonatal exposure to BDE-99, followed by BPA and PCB, produced the greatest persistent changes in the adult hepatic transcriptome, including an inflammation and cancer-prone transcriptomic signature. BDE-99 exposure resulted in a persistent increase in <i>Akkermansia muciniphila</i> throughout the intestinal sections and feces. We observed persistent increases in acetate and succinate, metabolites <i>A. muciniphila</i><span> is able to produce.</span> Correspondingly, liver H3K4me1 and H3K27 acetylation were enriched around the loci encoding liver cancer-related genes following neonatal BDE-99 exposure. </span></span></span></p> <p class="western"><span><span><span><b>Conclusion. </b><span>Similar to BPA, early life exposure to BDE-99 also produced a cancer-prone hepatic transcriptomic signature corresponding to an increase in permissive epigenetic signatures around cancer-related genes in adulthood. This positively associates with BDE-99 mediated increase in </span><i><span>A. muciniphila</span></i><span> and its metabolites which are established epigenetic modifiers. </span></span></span></span></p>
An EPIC Based BPA to Enhance Quit Line Referral and Use
ClinicalTrials.gov study NCT03229356. IPD Sharing: NO. Countries: 1. Publications: 9.
Neonatal exposure to BPA, BDE-99, and PCB produces persistent changes in hepatic transcriptome associated with gut dysbiosis in adult mouse livers
Open the record for dataset details and reuse information.
Data for: Feeding frequency does not interact with BPA exposure to influence metabolism of behaviour in zebrafish (Danio rerio)
Open the record for dataset details and reuse information.
Automatically measured birch pollen grains from the KM23B and Li-BPa records
<p>The data set includes pollen grain images produced for the manuscript "First automatic size measurements for the separation of dwarf birch and tree birch pollen in MIS 6 to MIS 1 records from Northern Germany". </p> <p>The images are cut-outs of birch pollen produced to automatically determine the size (area and mean diameter) of birch pollen grains. </p> <p>The workflow includes the following three steps, each of which is conducted using trained convoulutional neural networks: </p> <ol> <li>automatic detection and classification of pollen with the Tofsi algorithm (Theuerkauf et al. 2023, https://doi.org/10.1177/09596836231211876)</li> <li>automatic distinction between pollen grain suitable (i.e. in polar view) or not suitable (some other orientation) for size measurement </li> <li>automatic outline detection and size measurement (the green area indicates the area that was identified as the area of each pollen grain) </li> </ol>
Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled Trial
ClinicalTrials.gov study NCT04620486. IPD Sharing: NO. Countries: 1. Publications: 1.
BPA vs. PEA in CTEPH
ClinicalTrials.gov study NCT05110066. IPD Sharing: YES. Countries: 2. Publications: 14.
International BPA Registry
ClinicalTrials.gov study NCT03245268. IPD Sharing: Not stated. Countries: 10. Publications: 1.
Boronophenylalanine-Fructose Complex (BPA-F) and/or Sodium Borocaptate (BSH) Followed By Surgery in Treating Patients With Thyroid Cancer, Head and Neck Cancer, or Liver Metastases
ClinicalTrials.gov study NCT00062348. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Boronophenylalanine (BPA)-Based Boron Neutron Capture Therapy (BNCT) in the Treatment Head and Neck Tumors
ClinicalTrials.gov study NCT00114790. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Potential Effect of Dialyzer Leaching of BPA From the Fresenius Optiflux 160NR Compared to the Nipro ELISIO-15H
ClinicalTrials.gov study NCT02627118. IPD Sharing: Not stated. Countries: 0. Publications: 5.
THERAPY-HYBRID-BPA Trial
ClinicalTrials.gov study NCT04600492. IPD Sharing: Not stated. Countries: 1. Publications: 7.
BPA Biomonitoring Study in Cashiers
ClinicalTrials.gov study NCT01287169. IPD Sharing: Not stated. Countries: 0. Publications: 3.
In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
GEO Series GSE211183. Homo sapiens; synthetic construct. 768 samples. Type: Expression profiling by high throughput sequencing.
RNA-sequencing of Control and Bisphenol A (BPA) exposed mice livers.
GEO Series GSE155845. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Effects of BPA, BPF and BPS treatments on mESC EB-based global and neural differentiations.
GEO Series GSE120224. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.