Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
7
datasets available to search
ShareScore release 0.9.0
Dataset results
7 results for “Bayesian divergence time estimation”
Scalable Bayesian divergence time estimation with ratio transformations
<div class="page"> <div class="layoutArea"> <div class="column"> <p><span>Divergence time estimation is crucial to provide temporal signals for dating bio</span><span>logically important events, from species divergence to viral transmissions in space and </span><span>time. With the advent of high-throughput sequencing, recent Bayesian phylogenetic </span><span>studies have analyzed hundreds to thousands of sequences. Such large-scale analyses</span><span> </span><span>challenge divergence time reconstruction by requiring inference on highly-correlated</span><span> </span><span>internal node heights that often become computationally infeasible. To overcome this</span><span> </span><span>limitation, we explore a ratio transformation that maps the original </span><span>N - </span><span>1 internal</span><span> </span><span>node heights into a space of one height parameter and </span><span>N - </span><span>2 ratio parameters. To</span><span> </span><span>make the analyses scalable, we develop a collection of linear-time algorithms to com</span><span>pute the gradient and Jacobian-associated terms of the log-likelihood with respect to </span><span>these ratios. We then apply Hamiltonian Monte Carlo sampling with the ratio trans</span><span>form in a Bayesian framework to learn the divergence times in four pathogenic viruses</span><span> </span><span>(West Nile virus, rabies virus, Lassa virus and Ebola virus) and the coralline red algae.</span><span> </span><span>Our method both resolves a mixing issue in the West Nile virus example and improves</span><span> </span><span>inference efficiency by at least 5-fold for the Lassa and rabies virus examples as well</span><span> </span><span>as for the algae example. Our method now also makes it computationally feasible to</span><span> </span><span>incorporate mixed-effects molecular clock models for the Ebola virus example, confirms</span><span> </span><span>the findings from the original study and reveals clearer multimodal distributions of the</span><span> </span><span>divergence times of some clades of interest.</span></p> </div> </div> </div>
Scalable Bayesian divergence time estimation with ratio transformations
Open the record for dataset details and reuse information.
Data from: Bayesian divergence-time estimation with genome-wide SNP data of sea catfishes (Ariidae) supports Miocene closure of the Panamanian isthmus
Open the record for dataset details and reuse information.
Data from: Bayesian estimation of species divergence times using correlated quantitative characters
Discrete morphological data have been widely used to study species evolution, but the use of quantitative (or continuous) morphological characters is less common. Here, we implement a Bayesian method to estimate species divergence times using quantitative characters. Quantitative character evolution is modelled using Brownian diffusion with character correlation and character variation within populations. Through simulations, we demonstrate that ignoring the population variation (or population "noise") and the correlation among characters leads to biased estimates of divergence times and rate, especially if the correlation and population noise are high. We apply our new method to the analysis of quantitative characters (cranium landmarks) and molecular data from carnivoran mammals. Our results show that time estimates are affected by whether the correlations and population noise are accounted for or ignored in the analysis. The estimates are also affected by the type of data analysed, with analyses of morphological characters only, molecular data only, or a combination of both; showing noticeable differences among the time estimates. Rate variation of morphological characters among the carnivoran species appears to be very high, with Bayesian model selection indicating that the independent-rates model fits the morphological data better than the autocorrelated-rates model. We suggest that using morphological continuous characters, together with molecular data, can bring a new perspective to the study of species evolution. Our new model is implemented in the MCMCtree computer program for Bayesian inference of divergence times.
Data from: An evaluation of different partitioning strategies for Bayesian estimation of species divergence times
Open the record for dataset details and reuse information.
Data from: A hierarchical Bayesian model for calibrating estimates of species divergence times
Open the record for dataset details and reuse information.
Data from: Bayesian estimation of species divergence times using correlated quantitative characters
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.